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Selenoprotein K Products

(Selenoprotein K (SELK))

Categories

The protein encoded by this gene belongs to the selenoprotein K family. It is a transmembrane protein that is localized in the endoplasmic reticulum (ER), and is involved in ER-associated degradation (ERAD) of misfolded, glycosylated proteins. It also has a role in the protection of cells from ER stress-induced apoptosis. Knockout studies in mice show the importance of this gene in promoting Ca(2+) flux in immune cells and mounting effective immune response. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Pseudogenes of this locus have been identified on chromosomes 6 and 19.[provided by RefSeq, Aug 2017]

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Featured Selenoprotein K Categories

Selenoprotein K Antibodies

High quality antibodies with extensive validation data.

Selenoprotein K Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Selenoprotein K Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (1)
  • (2)
Cat. No. ABIN657518
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN566191
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN2502208
Quantity 400 μL
Datasheet Datasheet

Recommended Selenoprotein K ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6206082
Quantity 96 tests
Datasheet Datasheet

Recommended Selenoprotein K Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3130314
Quantity 0.25 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3076593
Quantity 0.5 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319449
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our Selenoprotein K products

Fredericks, Hoffmann, Rose, Osterheld, Hess, Mercier, Hoffmann: "Stable expression and function of the inositol 1,4,5-triphosphate receptor requires palmitoylation by a DHHC6/selenoprotein K complex." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 46, pp. 16478-83, (2014) (PubMed).

Synonyms and alternative names related to Selenoprotein K

selenoprotein K (SELENOK)
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