Secreted Frizzled-Related Protein 1 Products
(Secreted Frizzled-Related Protein 1 (SFRP1))
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This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling\; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq, Sep 2009].
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Featured Secreted Frizzled-Related Protein 1 Categories
Secreted Frizzled-Related Protein 1 Antibodies
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Secreted Frizzled-Related Protein 1 ELISA Kits
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Secreted Frizzled-Related Protein 1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Secreted Frizzled-Related Protein 1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7436171
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (3)
- (3)
Cat. No.
ABIN652980
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
- (3)
Cat. No.
ABIN129592
Quantity
100 μg
Datasheet
Datasheet
Recommended Secreted Frizzled-Related Protein 1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
- (1)
Cat. No.
ABIN6959284
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959285
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959286
Quantity
96 tests
Datasheet
Datasheet
Recommended Secreted Frizzled-Related Protein 1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7275578
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319735
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3076880
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Secreted Frizzled-Related Protein 1 products
: "sFRP1 protects H9c2 cardiac myoblasts from doxorubicin-induced apoptosis by inhibiting the Wnt/PCP-JNK pathway." in: Acta pharmacologica Sinica, Vol. 41, Issue 9, pp. 1150-1157, (2020) (PubMed).: "PHF21B overexpression promotes cancer stem cell-like traits in prostate cancer cells by activating the Wnt/β-catenin signaling pathway." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 85, (2018) (PubMed).
: "Correlation of blood bone turnover biomarkers and Wnt signaling antagonists with AS, DISH, OPLL, and OYL." in: BMC musculoskeletal disorders, Vol. 18, Issue 1, pp. 61, (2017) (PubMed).
: "Effects of exercise training on circulating levels of Dickkpof-1 and secreted frizzled-related protein-1 in breast cancer survivors: A pilot single-blind randomized controlled trial." in: PLoS ONE, Vol. 12, Issue 2, pp. e0171771, (2017) (PubMed).
: "Wnt inhibition is dysregulated in gliomas and its re-establishment inhibits proliferation and tumor sphere formation." in: Experimental cell research, Vol. 340, Issue 1, pp. 53-61, (2016) (PubMed).
: "Ophiopogonin D inhibits cell proliferation, causes cell cycle arrest at G2/M, and induces apoptosis in human breast carcinoma MCF-7 cells." in: Journal of integrative medicine, Vol. 14, Issue 1, pp. 51-9, (2016) (PubMed).
: "Expression and prognostic value of SFRP1 and β-catenin in patients with glioblastoma." in: Oncology letters, Vol. 11, Issue 1, pp. 69-74, (2016) (PubMed).
: "MiR-27a regulates Wnt/beta-catenin signaling through targeting SFRP1 in glioma." in: Neuroreport, Vol. 26, Issue 12, pp. 695-702, (2015) (PubMed).
: "Deregulation of secreted frizzled-related proteins is associated with aberrant β-catenin activation in the carcinogenesis of oral submucous fibrosis." in: OncoTargets and therapy, Vol. 8, pp. 2923-31, (2015) (PubMed).
: "Biomarkers and cytokines of bone turnover: extensive evaluation in a cohort of patients with ankylosing spondylitis." in: BMC musculoskeletal disorders, Vol. 13, pp. 191, (2012) (PubMed).
Synonyms and alternative names related to Secreted Frizzled-Related Protein 1
secreted frizzled related protein 1 (SFRP1), secreted frizzled-related protein 1 (Sfrp1), secreted frizzled-related protein 1 (sfrp1), secreted frizzled related protein 1 (sfrp1), Secreted frizzled-related protein 1 (sfrp1), secreted frizzled related protein 1 (Sfrp1), secreted frizzled-related protein 1a (sfrp1a), secreted frizzled-related protein 1b (sfrp1b), 2210415K03Rik, AW011917, AW107218, AW742929, CSFRP1, FRP, frp, FRP-1, frp-1, FRP1, frp1, FrzA, frzA, LOC100231868, SARP2, sarp2, sFRP-1, SFRP1, sfrp1, Srfp1a, wu:fd19b09, XfrzAProtein level used designations for Secreted Frizzled-Related Protein 1
- SARP-2
- sFRP-1
- secreted apoptosis-related protein 2
- secreted frizzled-related sequence protein 1
- frizzled in aorta protein
- frzA protein
- secreted frizzled related protein 1
- secreted frizzled-related protein 1
- Secreted frizzled-related protein 1
- secreted frizzled-related protein 1a
- secreted frizzled-related protein 1b
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