Mouse anti-Human IgG1 (Hinge Region) Antibody (PE)

Catalog No. ABIN135627

Quick Overview for Mouse anti-Human IgG1 (Hinge Region) Antibody (PE) (ABIN135627)

Target: IgG1

Clonality: Monoclonal

Conjugate: PE

Application: Flow Cytometry (FACS), FLISA, Multiplex Assay (MA)

Clone: 4E3

Isotype: IgG1

Product Details

Binding Specificity: Hinge Region

Reactivity: Human

Host: Mouse

Purpose: Mouse Anti-Human IgG1 Hinge-PE

Specificity: Reacts with the hinge region of the heavy chain of human IgG1 as demonstrated by ELISA

Characteristics: PE Anti-Human IgG1 Hinge antibody for use in flow cytometry and multiplex assays.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: Phosphate buffered saline containing < 0.1 % sodium azide and a stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C

References

Karsten, Mehta, Shin, Diefenbach, Slein, Karpinski, Irvine, Broge, Suscovich, Alter: "A versatile high-throughput assay to characterize antibody-mediated neutrophil phagocytosis." in: Journal of immunological methods, Vol. 471, pp. 46-56, (2019) (PubMed).

Violari, Cotton, Kuhn, Schramm, Paximadis, Loubser, Shalekoff, Da Costa Dias, Otwombe, Liberty, McIntyre, Babiker, Gibb, Tiemessen: "A child with perinatal HIV infection and long-term sustained virological control following antiretroviral treatment cessation." in: Nature communications, Vol. 10, Issue 1, pp. 412, (2019) (PubMed).

Boesch, Kappel, Mahan, Chu, Crowley, Osei-Owusu, Alter, Ackerman: "Enrichment of high affinity subclasses and glycoforms from serum-derived IgG using FcγRs as affinity ligands." in: Biotechnology and bioengineering, Vol. 115, Issue 5, pp. 1265-1278, (2019) (PubMed).

Target Details

Target: IgG1

Target Type: Antibody

Background:

Description: Mouse Anti-Human IgG1 Hinge-PE

NCBI_Official_Symbol: IGHG1

Gene ID: 3500

UniProt: P01857