Mouse anti-Rabbit IgM (Heavy & Light Chain) Antibody (Cy5)

Catalog No. ABIN2176908

Quick Overview for Mouse anti-Rabbit IgM (Heavy & Light Chain) Antibody (Cy5) (ABIN2176908)

Target: IgM

Clonality: Polyclonal

Conjugate: Cy5

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Isotype: IgM

Product Details

Binding Specificity: Heavy & Light Chain

Reactivity: Rabbit

Host: Mouse

Purpose: Mouse Anti-Rabbit IgM Antibody (H+L), Cy5 Conjugated

Cross-Reactivity: Rabbit

Purification: Purified by Protein A.

Application Details

Application Notes: WB(1:300-5000), FCM(1:20-100), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

References

Li, Sun, Zhang, Huang: "Time-staggered delivery of docetaxel and H1-S6A,F8A peptide for sequential dual-strike chemotherapy through tumor priming and nuclear targeting." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 232, pp. 62-74, (2016) (PubMed).

Guan, Li, Zhu, Yang, Zhang, Huang: "An in vitro investigation of a detachable fork-like structure as efficient nuclear-targeted sub-unit in A2780 cell cultures." in: International journal of pharmaceutics, Vol. 500, Issue 1-2, pp. 100-9, (2016) (PubMed).

Target Details

Target: IgM

Target Type: Antibody

Background: Synonyms: Immunoglobulin IgM normally constitutes about 10 % of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells.