Goat anti-Human IgD Antibody (PE)

Catalog No. ABIN376508

Quick Overview for Goat anti-Human IgD Antibody (PE) (ABIN376508)

Target: IgD

Clonality: Polyclonal

Conjugate: PE

Application: Flow Cytometry (FACS), FLISA

Isotype: IgG

Product Details

Reactivity: Human

Host: Goat

Purpose: Goat Anti-Human IgD-PE

Specificity: Reacts with the heavy chain of human IgD

Characteristics: Goat Anti-Human IgD-PE antibody for use in flow cytometry assays.

Purification: Purified by affinity chromatography on human IgD covalently linked to agarose, cross-adsorbed against human IgG, IgM, and IgA for minimal reactivity

Immunogen: Human IgD

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Pooled antisera from goats hyperimmunized with human IgD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline containing < 0.1 % sodium azide and a stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C

References

Han, Jones, Nicely, Reed, Shen, Mansouri, Louder, Trama, Alam, Edwards, Bonsignori, Tomaras, Korber, Montefiori, Mascola, Seaman, Haynes, Saunders: "Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations." in: Nature communications, Vol. 10, Issue 1, pp. 2898, (2019) (PubMed).

Blasi, Negri, LaBranche, Alam, Baker, Brunner, Gladden, Michelini, Vandergrift, Wiehe, Parks, Shen, Bonsignori, Tomaras, Ferrari, Montefiori, Santra, Haynes, Moody, Cara, Klotman: "IDLV-HIV-1 Env vaccination in non-human primates induces affinity maturation of antigen-specific memory B cells." in: Communications biology, Vol. 1, pp. 134, (2018) (PubMed).

Williams, Zhang, Jiang, Nicely, Fera, Luo, Moody, Liao, Alam, Kepler, Ramesh, Wiehe, Holland, Bradley, Vandergrift, Saunders, Parks, Foulger, Xia, Bonsignori, Montefiori, Louder, Eaton, Santra et al.: "Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations. ..." in: Nature communications, Vol. 8, Issue 1, pp. 1732, (2018) (PubMed).

Bradley, Pollara, Santra, Vandergrift, Pittala, Bailey-Kellogg, Shen, Parks, Goodman, Eaton, Balachandran, Mach, Saunders, Weiner, Scearce, Sutherland, Phogat, Tartaglia, Reed, Hu, Theis, Pinter et al.: "Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge. ..." in: Nature communications, Vol. 8, pp. 15711, (2018) (PubMed).

Hammarlund, Thomas, Amanna, Holden, Slayden, Park, Gao, Slifka: "Plasma cell survival in the absence of B cell memory." in: Nature communications, Vol. 8, Issue 1, pp. 1781, (2018) (PubMed).

Target Details

Target: IgD

Target Type: Antibody

Background:

Description: Goat Anti-Human IgD-PE

NCBI_Official_Symbol: IGHD

Gene ID: 3495

UniProt: P01880