Mouse anti-Human IgG3 (Hinge Region) Antibody (PE)

Catalog No. ABIN376575

Quick Overview for Mouse anti-Human IgG3 (Hinge Region) Antibody (PE) (ABIN376575)

Target: IgG3

Clonality: Monoclonal

Conjugate: PE

Application: Flow Cytometry (FACS), FLISA, Multiplex Assay (MA)

Clone: HP6050

Isotype: IgG1

Product Details

Binding Specificity: Hinge Region

Reactivity: Human

Host: Mouse

Purpose: Mouse Anti-Human IgG3 Hinge-PE

Specificity: Human IgG3 Hinge, Mr 170 kDa

Characteristics: PE Anti-Human IgG3 Hinge antibody for use in flow cytometry and multiplex assays.

Immunogen: Human IgG3 myeloma protein

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: Phosphate buffered saline containing < 0.1 % sodium azide and a stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C

References

Violari, Cotton, Kuhn, Schramm, Paximadis, Loubser, Shalekoff, Da Costa Dias, Otwombe, Liberty, McIntyre, Babiker, Gibb, Tiemessen: "A child with perinatal HIV infection and long-term sustained virological control following antiretroviral treatment cessation." in: Nature communications, Vol. 10, Issue 1, pp. 412, (2019) (PubMed).

Howie, Delaney, Wang, Er, Vidarsson, Stegmann, Kapp, Lebedev, Wu, AuBuchon, Zimring: "Serological blind spots for variants of human IgG3 and IgG4 by a commonly used anti-immunoglobulin reagent." in: Transfusion, Vol. 56, Issue 12, pp. 2953-2962, (2017) (PubMed).

Bentall, Tyan, Sequeira, Everly, Gandhi, Cornell, Li, Henderson, Raghavaiah, Winters, Dean, Stegall: "Antibody-Mediated Rejection Despite Inhibition of Terminal Complement." in: Transplant international : official journal of the European Society for Organ Transplantation, (2014) (PubMed).

Target Details

Target: IgG3

Target Type: Antibody

Background:

Description: Mouse Anti-Human IgG3 Hinge-PE

NCBI_Official_Symbol: IGHG3

Gene ID: 3502

UniProt: P01860