Goat anti-Mouse IgA Antibody (PE)

Catalog No. ABIN4369384

Quick Overview for Goat anti-Mouse IgA Antibody (PE) (ABIN4369384)

Target: IgA

Clonality: Polyclonal

Conjugate: PE

Application: Flow Cytometry (FACS), FLISA

Isotype: IgG

Product Details

Reactivity: Mouse

Host: Goat

Purpose: Goat Anti-Mouse IgA-PE

Specificity: Reacts with the heavy chain of mouse IgA

Characteristics: Goat Anti-Mouse IgA-PE antibody for use in flow cytometry assays

Purification: Purified by affinity chromatography on mouse IgA covalently linked to agarose, cross-adsorbed against mouse IgG and IgM for minimal reactivity

Immunogen: Mouse IgA

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Pooled antisera from goats hyperimmunized with mouse IgA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline containing < 0.1 % sodium azide and a stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C

References

Sundaravinayagam, Rahjouei, Andreani, Tupiņa, Balasubramanian, Saha, Delgado-Benito, Coralluzzo, Daumke, Di Virgilio: "53BP1 Supports Immunoglobulin Class Switch Recombination Independently of Its DNA Double-Strand Break End Protection Function." in: Cell reports, Vol. 28, Issue 6, pp. 1389-1399.e6, (2019) (PubMed).

Delgado-Benito, Rosen, Wang, Gazumyan, Pai, Oliveira, Sundaravinayagam, Zhang, Andreani, Keller, Kieffer-Kwon, Pękowska, Jung, Driesner, Subbotin, Casellas, Chait, Nussenzweig, Di Virgilio: "The Chromatin Reader ZMYND8 Regulates Igh Enhancers to Promote Immunoglobulin Class Switch Recombination." in: Molecular cell, Vol. 72, Issue 4, pp. 636-649.e8, (2019) (PubMed).

Li, Irrazabal, So, Berru, Du, Lam, Ling, Gommerman, Pan-Hammarström, Martin: "The H2B deubiquitinase Usp22 promotes antibody class switch recombination by facilitating non-homologous end joining." in: Nature communications, Vol. 9, Issue 1, pp. 1006, (2018) (PubMed).

Target Details

Target: IgA

Target Type: Antibody

Background:

Description: Goat Anti-Mouse IgA-PE

NCBI_Official_Symbol: Igha

Gene ID: 238447