Mouse anti-Human IgM Antibody (iFluor™700)

Catalog No. ABIN7077569

Product Details

Target: IgM

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: iFluor™700

Characteristics: The  clone  M--2E6,  a  mouse  monoclonal  antibody  selectively  recognizes  the  epitope  present  in  the  Fab  arms  (anti- Fdμ)  of  the  surface  monomeric  IgM  molecule  on  B  cells.  It  reduces  the  growth  of  the  neoplastic  B  cells  through  its   intrinsic  crosslinking  property  in  vitro.  IgM  is  the  first  immunoglobulin  expressed  in  the  human  fetus  at  around  20   weeks.  It  plays  various  important  immunological  roles  in  protecting  host  from  the  viral  and  bacterial  infections  as   well  as  from  the  autoimmune  diseases.

Purification: Purified

Purity: >95 %

Grade: GMP Grade

Immunogen: Purified human IgM

Clone: M-2E6

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details

Target: IgM

Abstract: IgM Products

Target Type: Antibody

Background: The  clone  M--2E6,  a  mouse  monoclonal  antibody  selectively  recognizes  the  epitope  present  in  the  Fab  arms  (anti- Fdμ)  of  the  surface  monomeric  IgM  molecule  on  B  cells.  It  reduces  the  growth  of  the  neoplastic  B  cells  through  its   intrinsic  crosslinking  property  in  vitro.  IgM  is  the  first  immunoglobulin  expressed  in  the  human  fetus  at  around  20   weeks.  It  plays  various  important  immunological  roles  in  protecting  host  from  the  viral  and  bacterial  infections  as   well  as  from  the  autoimmune  diseases.

Gene ID: 959

UniProt: P29965