SHANK1 Products
(SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1))
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Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction.
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SHANK1 Antibodies
High quality antibodies with extensive validation data.
SHANK1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Recommended SHANK1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, IHC, AA
Validations
- (3)
Cat. No.
ABIN863122
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, AA
Validations
- (3)
Cat. No.
ABIN2483711
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, AA
Validations
- (3)
Cat. No.
ABIN2483710
Quantity
100 μg
Datasheet
Datasheet
Recommended SHANK1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6210168
Quantity
96 tests
Datasheet
Datasheet
Latest Publications for our SHANK1 products
: "Transgenerational Bisphenol A Causes Deficits in Social Recognition and Alters Postsynaptic Density Genes in Mice." in: Endocrinology, Vol. 160, Issue 8, pp. 1854-1867, (2019) (PubMed).: "USP8 Deubiquitinates SHANK3 to Control Synapse Density and SHANK3 Activity-Dependent Protein Levels." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 38, Issue 23, pp. 5289-5301, (2018) (PubMed).
: "Selective Localization of Shanks to VGLUT1-Positive Excitatory Synapses in the Mouse Hippocampus." in: Frontiers in cellular neuroscience, Vol. 10, pp. 106, (2016) (PubMed).
: "Electron tomographic structure and protein composition of isolated rat cerebellar, hippocampal and cortical postsynaptic densities." in: Neuroscience, Vol. 304, pp. 286-301, (2015) (PubMed).
: "Deletion of Shank1 has minimal effects on the molecular composition and function of glutamatergic afferent postsynapses in the mouse inner ear." in: Hearing research, Vol. 321, pp. 52-64, (2015) (PubMed).
: "Effects of trace metal profiles characteristic for autism on synapses in cultured neurons." in: Neural plasticity, Vol. 2015, pp. 985083, (2015) (PubMed).
: "Hyperactivity of newborn Pten knock-out neurons results from increased excitatory synaptic drive." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 3, pp. 943-59, (2015) (PubMed).
: "The potential use of H102 peptide-loaded dual-functional nanoparticles in the treatment of Alzheimer's disease." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 192, pp. 317-24, (2014) (PubMed).
: "Regulation of synapse composition by protein acetylation: the role of acetylated cortactin." in: Journal of cell science, Vol. 126, Issue Pt 1, pp. 149-62, (2013) (PubMed).
: "SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties." in: Nature, Vol. 503, Issue 7474, pp. 72-7, (2013) (PubMed).
Synonyms and alternative names related to SHANK1
SH3 and multiple ankyrin repeat domains 1 (SHANK1), SH3 and multiple ankyrin repeat domains 1 (Shank1), Shank1a, SPANK-1, Spank1, SSTRIP, Sstrip, synamonProtein level used designations for SHANK1
- SH3 and multiple ankyrin repeat domains protein 1
- SSTR-interacting protein
- somatostatin receptor-interacting protein
- GKAP/SAPAP interacting protein
- GKAP/SAPAP-interacting protein
- SAPAP-interacting protein synamon
- SH3/ankyrin domain gene 1
- SPANK-1
- synamon
- SH3 and multiple ankyrin repeat domains 1
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