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SLC39A4 Products

(Solute Carrier Family 39 (Zinc Transporter), Member 4 (SLC39A4))
This gene encodes a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The transmembrane protein is required for zinc uptake in the intestine. Mutations in this gene result in acrodermatitis enteropathica, a rare inherited defect in the absorption of dietary zinc. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured SLC39A4 Categories

SLC39A4 Antibodies

High quality antibodies with extensive validation data.

SLC39A4 ELISA Kits

Reliable ELISA kits for a wide range of species.

SLC39A4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SLC39A4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7176706
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, IF (cc), IF (p), ICC, IHC (fro), IHC (p)
Validations
  • (2)
Cat. No. ABIN5675382
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7176708
Quantity 100 μL
Datasheet Datasheet

Recommended SLC39A4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970340
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959600
Quantity 96 tests
Datasheet Datasheet

Recommended SLC39A4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3123971
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3076487
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3123969
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SLC39A4 products

Antala, Ovchinnikov, Kamisetty, Baker, Dempski: "Computation and Functional Studies Provide a Model for the Structure of the Zinc Transporter hZIP4." in: The Journal of biological chemistry, Vol. 290, Issue 29, pp. 17796-805, (2015) (PubMed).

Zhang, Bharadwaj, Logsdon, Chen, Yao, Li: "ZIP4 regulates pancreatic cancer cell growth by activating IL-6/STAT3 pathway through zinc finger transcription factor CREB." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 5, pp. 1423-30, (2010) (PubMed).

Li, Zhang, Bharadwaj, Zhai, Ahern, Fisher, Brunicardi, Logsdon, Chen, Yao: "Down-regulation of ZIP4 by RNA interference inhibits pancreatic cancer growth and increases the survival of nude mice with pancreatic cancer xenografts." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 19, pp. 5993-6001, (2009) (PubMed).

Li, Zhang, Liu, Bharadwaj, Wang, Wang, Zhang, Liuzzi, Chang, Cousins, Fisher, Brunicardi, Logsdon, Chen, Yao: "Aberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 47, pp. 18636-41, (2007) (PubMed).

Kim, Wang, Dufner-Beattie, Andrews, Eide, Petris: "Zn2+-stimulated endocytosis of the mZIP4 zinc transporter regulates its location at the plasma membrane." in: The Journal of biological chemistry, Vol. 279, Issue 6, pp. 4523-30, (2004) (PubMed).

Küry, Dréno, Bézieau, Giraudet, Kharfi, Kamoun, Moisan: "Identification of SLC39A4, a gene involved in acrodermatitis enteropathica." in: Nature genetics, Vol. 31, Issue 3, pp. 239-40, (2002) (PubMed).

Wang, Zhou, Kuo, Zemansky, Gitschier: "A novel member of a zinc transporter family is defective in acrodermatitis enteropathica." in: American journal of human genetics, Vol. 71, Issue 1, pp. 66-73, (2002) (PubMed).

Synonyms and alternative names related to SLC39A4

solute carrier family 39 member 4 (SLC39A4), solute carrier family 39 (zinc transporter), member 4 (slc39a4), solute carrier family 39 (zinc transporter), member 4 (Slc39a4), solute carrier family 39 member 4 (Slc39a4), 1600025H15Rik, AEZ, AU041686, AWMS2, ZIP4

Protein level used designations for SLC39A4

  • solute carrier family 39 (zinc transporter), member 4
  • ZIP4
  • zinc transporter ZIP4-like
  • zinc transporter ZIP4
  • zrt- and Irt-like protein 4
  • ZIP-4
  • solute carrier family 39 member 4
  • solute carrier family 39, member 4
  • activated in W/Wv mouse stomach 2
  • mAWMS2
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