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SNCA Proteins

(Synuclein, alpha (SNCA))
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009].

53 results

SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant CA
Catalog No. ABIN1882609
 
SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant
Catalog No. ABIN1882765
 
SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant
Catalog No. ABIN1882766
 
SNCA Origin: Cow Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN7588963
 
SNCA Origin: Pig Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1628089
 
SNCA Origin: Spider Monkey Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1468240
 
SNCA Origin: Chimpanzee Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1611230
 
SNCA Origin: Red-chested mustached Tamarin (Saguinus labiatus) Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1611122
 
SNCA Origin: Bonobo Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1611266
 
SNCA Origin: Woolly Monkey Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1611194
 
SNCA Origin: Orang-Utan Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1611195
 
SNCA Origin: Primate (Erythrocebus) Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1611161
 
SNCA Origin: Serinus canaria Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1638480
 
  • Type Protein
    • Protein
  • Application
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • In vitro Assay (in vitro)
    • In vivo Studies (in vivo)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Cellular Assay (CA)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Standard (STD)
    • Immunoprecipitation (IP)
  • Reactivity
    • Human
    • Mouse
    • Rat
    • Cynomolgus
    • Bonobo
    • Chimpanzee
    • Cow
    • Orang-Utan
    • Pig
    • Primate (Erythrocebus)
    • Red-chested mustached Tamarin (Saguinus labiatus)
    • Serinus canaria
    • Spider Monkey
    • Woolly Monkey
  • Cited in publications
  • Images available
  • Carrier free only
  • Host
    • Escherichia coli (E. coli)
    • Yeast
    • HEK-293 Cells
    • Cell-free protein synthesis (CFPS)
    • Wheat germ
  • Binding Specificity
    • AA 1-140
    • full length
    • A53T
    • AA 23-140
    • AA 1-139
    • AA 1-143
    • AA 1-60
    • AA 31-140
    • AA 61-140
    • AA 96-140
    • E46K
    • R30P
    • Transcript Variant 2
    • Transcript Variant 3
    • active
    • partial
  • Conjugate
    • His tag
    • Un-conjugated
    • GST tag
    • Myc-DYKDDDDK Tag
    • Strep Tag
    • Biotin
    • Fc Tag
    • HiLyte Fluor 488
    • His tag,AVI tag,Biotin
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biological Activity
    • Biologically Active
  • Grade
    • MALS verified
    • custom-made
  • Supplier
    • antibodies-online
    • CUSABIO
    • ACROBiosystems
    • Eurogentec
    • ITSI-Biosciences
    • OriGene
    • Signalway
    • Abbexa
    • Rockland

Latest Publications for our SNCA Proteins

Xu, Li, Qin, Zhu, Zhou, Shi, Wang, Hu, Fan, Li: "Unraveling the role of hydrogen peroxide in ?-synuclein aggregation using an ultrasensitive nanoplasmonic probe." in: Analytical chemistry, Vol. 87, Issue 3, pp. 1968-73, (2015) (PubMed).

Jüttner, Moré, Das, Babich, Meier, Henning, Erdmann, Mu Ller, Otto, Grantyn, Rathjen: "Impaired synapse function during postnatal development in the absence of CALEB, an EGF-like protein processed by neuronal activity." in: Neuron, Vol. 46, Issue 2, pp. 233-45, (2005) (PubMed).

Uéda, Saitoh, Mori: "Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid." in: Biochemical and biophysical research communications, Vol. 205, Issue 2, pp. 1366-72, (1995) (PubMed).

Campion, Martin, Heilig, Charbonnier, Moreau, Flaman, Petit, Hannequin, Brice, Frebourg: "The NACP/synuclein gene: chromosomal assignment and screening for alterations in Alzheimer disease." in: Genomics, Vol. 26, Issue 2, pp. 254-7, (1995) (PubMed).

Uéda, Fukushima, Masliah, Xia, Iwai, Yoshimoto, Otero, Kondo, Ihara, Saitoh: "Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 23, pp. 11282-6, (1994) (PubMed).

Aliases for SNCA Proteins

synuclein alpha L homeolog (snca.L) Proteins
alpha-synuclein (LOC619283) Proteins
synuclein alpha (SNCA) Proteins
synuclein, alpha (Snca) Proteins
synuclein alpha (Snca) Proteins
alphaSYN Proteins
LOC619283 Proteins
MGC64356 Proteins
NACP Proteins
PARK1 Proteins
PARK4 Proteins
PD1 Proteins
snca Proteins
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