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SPEN Antibodies

(Spen Homolog, Transcriptional Regulator (SPEN))
This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator\; this binding can modulate the activity of both liganded and nonliganded steroid receptors. [provided by RefSeq, Jul 2008].
SPEN antibody SPEN antibody SPEN antibody (ABIN5588624)

SPEN Reactivity: Human IF, IHC (p) Host: Rabbit Polyclonal unconjugated

SPEN antibody (Internal Region) (ABIN185595)

Recent SPEN Reactivity: Human ELISA Host: Goat Polyclonal unconjugated

SPEN antibody (ABIN7096817)

SPEN Reactivity: Human, Mouse ELISA Host: Rabbit Polyclonal unconjugated

SPEN Antibodies by Grade

Find SPEN Antibodies with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

SPEN Antibodies by Reactivity

Find SPEN Antibodies for a variety of species such as anti-Human SPEN, anti-Mouse SPEN, anti-Dog SPEN. The species listed below are among those available. Click on a link to go to the corresponding products.

SPEN Antibodies by Application

Find SPEN Antibodies validated for a specific application such as ELISA, IP, IF, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

SPEN Antibodies by Host

Find SPEN Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

SPEN Antibodies by Binding Specificity

Find SPEN Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

SPEN Antibodies by Clonality

Find available monoclonal or polyclonal SPEN Antibodies. Click on a link to go to the corresponding products.

Popular SPEN Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IF, IHC (p)
Validations
  • (2)
Cat. No. ABIN5588624
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN185595
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA
Validations
Cat. No. ABIN7096817
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Guinea Pig, Horse, Human, Mouse, Rabbit
Application IP
Validations
Cat. No. ABIN1937727
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application IP
Validations
Cat. No. ABIN1937728
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our SPEN Antibodies

Korfanty, Stokowy, Chadalski, Toma-Jonik, Vydra, Widłak, Wojtaś, Gielniewski, Widlak: "SPEN protein expression and interactions with chromatin in mouse testicular cells." in: Reproduction (Cambridge, England), Vol. 156, Issue 3, pp. 195-206, (2018) (PubMed).

McHugh, Chen, Chow, Surka, Tran, McDonel, Pandya-Jones, Blanco, Burghard, Moradian, Sweredoski, Shishkin, Su, Lander, Hess, Plath, Guttman: "The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3." in: Nature, Vol. 521, Issue 7551, pp. 232-6, (2015) (PubMed).

Hiriart, Gruffat, Buisson, Mikaelian, Keppler, Meresse, Mercher, Bernard, Sergeant, Manet: "Interaction of the Epstein-Barr virus mRNA export factor EB2 with human Spen proteins SHARP, OTT1, and a novel member of the family, OTT3, links Spen proteins with splicing regulation and mRNA export." in: The Journal of biological chemistry, Vol. 280, Issue 44, pp. 36935-45, (2005) (PubMed).

Aliases for SPEN Antibodies

spen family transcriptional repressor (SPEN) Antibodies
SPEN homolog, transcriptional regulator (Drosophila) (Spen) Antibodies
HIAA0929 Antibodies
MINT Antibodies
Mint Antibodies
mKIAA0929 Antibodies
RBM15C Antibodies
SHARP Antibodies
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