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TCP1 alpha/CCTA Products

(T-Complex 1 (TCP1))
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found. [provided by RefSeq, Jun 2010].

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Featured TCP1 alpha/CCTA Categories

TCP1 alpha/CCTA Antibodies

High quality antibodies with extensive validation data.

TCP1 alpha/CCTA ELISA Kits

Reliable ELISA kits for a wide range of species.

TCP1 alpha/CCTA Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TCP1 alpha/CCTA Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (1)
  • (5)
Cat. No. ABIN563128
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF, FACS
Validations
  • (5)
Cat. No. ABIN185185
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ICC, IHC (p)
Validations
  • (8)
Cat. No. ABIN3029087
Quantity 100 μg
Datasheet Datasheet

Recommended TCP1 alpha/CCTA ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380868
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380315
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative DNA-Binding ELISA
Validations
Cat. No. ABIN5648646
Quantity 96 tests
Datasheet Datasheet

Recommended TCP1 alpha/CCTA Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1322407
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125306
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7529160
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TCP1 alpha/CCTA products

Quantius, Schmoldt, Vazquez-Armendariz, Becker, El Agha, Wilhelm, Morty, Vadász, Mayer, Gattenloehner, Fink, Matrosovich, Li, Seeger, Lohmeyer, Bellusci, Herold: "Influenza Virus Infects Epithelial Stem/Progenitor Cells of the Distal Lung: Impact on Fgfr2b-Driven Epithelial Repair." in: PLoS pathogens, Vol. 12, Issue 6, pp. e1005544, (2016) (PubMed).

Drier, Cotton, Williamson, Gillespie, Ryan, Kluk, Carey, Rodig, Sholl, Afrogheh, Faquin, Queimado, Qi, Wick, El-Naggar, Bradner, Moskaluk, Aster, Knoechel, Bernstein: "An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma." in: Nature genetics, Vol. 48, Issue 3, pp. 265-72, (2016) (PubMed).

Katoh, Fukunishi, Fujimuro, Kasai, Moriishi, Hata, Kurata: "Repression of Wnt/β-catenin response elements by p63 (TP63)." in: Cell cycle (Georgetown, Tex.), Vol. 15, Issue 5, pp. 699-710, (2016) (PubMed).

Yang, Xie, Shu, Liu, Chen, Ruan, Qi: "An improved method for the isolation and culture of rat epidermal stem cells." in: International journal of clinical and experimental pathology, Vol. 6, Issue 11, pp. 2529-34, (2014) (PubMed).

Rhie, Hazelett, Coetzee, Yan, Noushmehr, Coetzee: "Nucleosome positioning and histone modifications define relationships between regulatory elements and nearby gene expression in breast epithelial cells." in: BMC genomics, Vol. 15, pp. 331, (2014) (PubMed).

Hirai, Maeda, Omori, Yamamoto, Kokeguchi, Takashiba: "Serum antibody response to group II chaperonin from Methanobrevibacter oralis and human chaperonin CCT." in: Pathogens and disease, Vol. 68, Issue 1, pp. 12-9, (2013) (PubMed).

Satish, Lo, Gallo, Johnson, Haberman, Kathju: "Chaperonin containing T-complex polypeptide (CCT) subunit expression in oral mucosal wounds and fibroblasts." in: Cell stress & chaperones, Vol. 16, Issue 6, pp. 675-80, (2011) (PubMed).

Seo, Baye, Schulz, Beck, Zhang, Slusarski, Sheffield: "BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 4, pp. 1488-93, (2010) (PubMed).

Gong, Guo, Huang, Sun: "Inhaled nitric oxide alleviates hyperoxia suppressed phosphatidylcholine synthesis in endotoxin-induced injury in mature rat lungs." in: Respiratory research, Vol. 7, pp. 5, (2006) (PubMed).

Hynes, Willison: "Individual subunits of the eukaryotic cytosolic chaperonin mediate interactions with binding sites located on subdomains of beta-actin." in: The Journal of biological chemistry, Vol. 275, Issue 25, pp. 18985-94, (2000) (PubMed).

Synonyms and alternative names related to TCP1 alpha/CCTA

t-complex 1 (TCP1), T-complex protein 1 subunit alpha (cct-1), t-complex protein 1 (Tcp1), t-complex 1 (Tcp1), Tcp1-like (T-cp1), t-complex 1 S homeolog (tcp1.S), t-complex 1 (tcp1), AI528772, BEST:GH05123, c-cpn, CCT, CCT-alpha, cct-alpha, CCT1, Cct1, CCTa, Ccta, ccta, CCTalpha, CG5374, CHUNP6875, D6S230E, Dmel\\CG5374, fa13h08, gh05123, p63, T-cpl, Tcp-1, TCP-1-alpha, TCP-1alpha, Tcp1, tcp1, tcp1-a, Tcp1-alpha, tcp1a, tcp1alpha, TCPA_DROME, Tp63, TRic, TRiC, wu:fa13h08, wu:fc95g06

Protein level used designations for TCP1 alpha/CCTA

  • T-complex protein 1 subunit alpha
  • T-complex protein 1, alpha subunit
  • tailless complex polypeptide 1
  • CCT-alpha
  • T-complex protein 1 subunit alpha A
  • T-complex protein 1 subunit alpha B
  • TCP-1-A
  • TCP-1-B
  • TCP-1-alpha
  • t-complex polypeptide 1
  • tailless complex polypeptide 1A
  • tailless complex polypeptide 1B
  • cytosolic chaperonin containing t-complex polypeptide 1
  • CG5374-PA
  • CG5374-PB
  • T-complex 1
  • T-cp1-PA
  • T-cp1-PB
  • 65 kDa antigen
  • t-complex 1
  • t-complex 1 S homeolog
  • cct1
  • T-complex protein 1 subunit alpha-like protein
  • chaperonin-containing T-complex polypeptide alpha subunit
  • T-complex protein 1 alpha subunit-like protein
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