Terb2 Protein (AA 1-218) (His tag)
custom-made
TERB_2
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target
- Terb2 (TERB_2) (Phage Inhibition, Colicin Resistance and Tellurite Resistance Protein (TERB_2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-218
- Origin
- Mouse
- Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Terb2 protein is labelled with His tag.
- Purpose
- Predefined custom protein recombinant Terb2 Protein expressed in mammalian cells.
- Sequence
- MFQGQRGWFC GSVSQDLRQI WEDEGGMVSD VKAADFLFSC DASHPDTLRI YQSLEYIEDN ATVFHAYYLA AIANTEMKNS VALGHFVLPP ACLQKEIRRK IGSFIWEQDE KFQIEKHDRM ASSDKENIRP TPEHKQELSK SAEHHLTRTP VIEKQMCFPL HSYPVNNMVT GYISIDALEK FLGELHDFTP GSSGYLAYHI QDEINMSAIK NKLRRKLS Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- Terb2 (TERB_2) (Phage Inhibition, Colicin Resistance and Tellurite Resistance Protein (TERB_2))
- Alternative Name
- Terb2
- Background
- Telomere repeats-binding bouquet formation protein 2,FUNCTION: Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex. During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA. {ECO:0000269|PubMed:26548954}.
- Molecular Weight
- 25.0 kDa
- UniProt
- Q9D494
- AlphaFold
- Q9D494
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