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TIGAR Proteins

(TP53 induced glycolysis regulatory phosphatase (TIGAR))
This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region. [provided by RefSeq, Jul 2008].

16 results

custom-made TIGAR Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catalog No. ABIN7564474
 
custom-made TIGAR Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catalog No. ABIN7555807
 
TIGAR Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Catalog No. ABIN7125420
 
TIGAR Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, WB, ELISA
Pubmed 1 reference
Catalog No. ABIN7579904
 
TIGAR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Catalog No. ABIN1347100
 
TIGAR Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % pure SDS
Catalog No. ABIN2132181
 
TIGAR Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC
Catalog No. ABIN7424359
 
TIGAR Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC
Catalog No. ABIN7424260
 
TIGAR Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC
Catalog No. ABIN7424257
 
custom-made TIGAR Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA
Catalog No. ABIN3136329
 
custom-made TIGAR Origin: Human Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA
Catalog No. ABIN3095990
 
TIGAR Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2733721
 
TIGAR Origin: Cow Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN7588034
 
TIGAR Origin: Human Host: Escherichia coli (E. coli) Recombinant >96 % as determined by SDS-PAGE and HPLC. Func Active
Catalog No. ABIN2830406
 
TIGAR Origin: Xenopus laevis Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1630159
 
TIGAR Origin: Xenopus tropicalis Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1611910
 
  • Type Protein
    • Protein
  • Application
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Standard (STD)
  • Reactivity
    • Human
    • Mouse
    • Cow
    • Rat
    • Xenopus laevis
    • Xenopus tropicalis
  • Cited in publications
  • Images available
  • Carrier free only
  • Host
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Yeast
    • Cell-free protein synthesis (CFPS)
    • Wheat germ
  • Binding Specificity
    • AA 1-270
    • AA 1-269
    • AA 1-275
    • AA 1-178
    • AA 2-270
  • Conjugate
    • His tag
    • Strep Tag
    • GST tag
    • Myc-DYKDDDDK Tag
    • TAT tag
    • Un-conjugated
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biological Activity
    • Biologically Active
  • Grade
    • custom-made
  • Supplier
    • antibodies-online
    • CUSABIO
    • OriGene

Latest Publications for our TIGAR Proteins

Qi, Zhang, Yang, Wang, Hu, Shen, Wan, Li, Liu, Deng: "Identification of TIGAR, a direct proteomic target associated with the hypoglycemic effect of Berberine." in: Fitoterapia, Vol. 180, pp. 106332, (2024) (PubMed).

Aliases for TIGAR Proteins

Trp53 induced glycolysis repulatory phosphatase (Tigar) Proteins
AA793651 Proteins
AI595337 Proteins
C79710 Proteins
C85509 Proteins
Tigar Proteins
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