TNFSF13 Proteins
(Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified\; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010].
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35 results
TNFSF13
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 97 %
SDS, WB, Imm, PC
TNFSF13
Origin: Rat
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
TNFSF13
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
TNFSF13
Origin: Cow
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
TNFSF13
Origin: Rhesus Monkey
Host: Escherichia coli (E. coli)
Recombinant
> 97 %
SDS, WB, Imm, PC
TNFSF13
Origin: Dog
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
TNFSF13
Origin: Human
Host: CHO Cells
Recombinant
>95 % (SDS-PAGE)
Active
TNFSF13
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by SDS-PAGE and Coomassie blue staining
AbP, Func, PI, STD
Active
1 image
TNFSF13
Origin: Rat
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, ELISA, IP
1 image
TNFSF13
Origin: Monkey
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, ELISA, IP
1 image
TNFSF13
Origin: Dog
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, ELISA, IP
1 image
MALS verified
TNFSF13
Origin: Cynomolgus
Host: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
TNFSF13
Origin: Human
Host: Human Cells
Recombinant
Greater than 95 % as determined by reducing SDS-PAGE.
SDS, WB, ELISA, MS
Latest Publications for our TNFSF13 Proteins
: "STAT-3 activation by differential cytokines is critical for human in vivo-generated plasma cell survival and Ig secretion." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 10, pp. 4996-5004, (2013) (PubMed).: "Selective APRIL blockade delays systemic lupus erythematosus in mouse." in: PLoS ONE, Vol. 7, Issue 2, pp. e31837, (2012) (PubMed).
: "Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 9, pp. 3701-6, (2011) (PubMed).
: "TACI regulates IgA production by APRIL in collaboration with HSPG." in: Blood, Vol. 109, Issue 7, pp. 2961-7, (2007) (PubMed).
: "BAFF and APRIL support chronic lymphocytic leukemia B-cell survival through activation of the canonical NF-kappaB pathway." in: Blood, Vol. 109, Issue 2, pp. 703-10, (2007) (PubMed).
: "APRIL and BAFF promote increased viability of replicating human B2 cells via mechanism involving cyclooxygenase 2." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 11, pp. 6736-51, (2006) (PubMed).
: "BAFF regulates B cell survival by downregulating the BH3-only family member Bim via the ERK pathway." in: The Journal of experimental medicine, Vol. 202, Issue 10, pp. 1363-74, (2005) (PubMed).
: "Potential role of APRIL as autocrine growth factor for megakaryocytopoiesis." in: Blood, Vol. 104, Issue 10, pp. 3169-72, (2004) (PubMed).
: "Lymphoma B cells evade apoptosis through the TNF family members BAFF/BLyS and APRIL." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 5, pp. 3268-79, (2004) (PubMed).
: "DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL." in: Nature immunology, Vol. 3, Issue 9, pp. 822-9, (2002) (PubMed).
Aliases for TNFSF13 Proteins
TNF superfamily member 13 (TNFSF13) Proteinstumor necrosis factor (ligand) superfamily, member 13 (Tnfsf13) Proteins
acidic leucine-rich nuclear phosphoprotein 32 family member B (LOC494442) Proteins
tumor necrosis factor (ligand) superfamily, member 13 (tnfsf13) Proteins
TNF superfamily member 13 (Tnfsf13) Proteins
tumor necrosis factor (ligand) superfamily, member 13 (TNFSF13) Proteins
2310026N09Rik Proteins
ANP32B Proteins
APRIL Proteins
April Proteins
april Proteins
CD256 Proteins
SLAN Proteins
TALL-2 Proteins
TALL2 Proteins
Tall2 Proteins
tnf13 Proteins
TNLG7B Proteins
TRDL-1 Proteins
Trdl1 Proteins
ZTNF2 Proteins
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