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TP53AIP1 Products

(P53-Regulated Apoptosis-Inducing Protein 1 (TP53AIP1))

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This gene is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important role in mediating p53-dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011].

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Featured TP53AIP1 Categories

TP53AIP1 Antibodies

High quality antibodies with extensive validation data.

TP53AIP1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TP53AIP1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7162470
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN872405
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7239317
Quantity 200 μL
Datasheet Datasheet

Recommended TP53AIP1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313842
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3074716
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TP53AIP1 products

Ohno, Naito, Mukai, Yabuta, Nojima: "ELAS1-mediated inhibition of the cyclin G1-B'γ interaction promotes cancer cell apoptosis via stabilization and activation of p53." in: Oncogene, Vol. 34, Issue 49, pp. 5983-96, (2016) (PubMed).

Igarashi, Hirano, Yahagi, Saika, Ishihara: "Anti-apoptotic roles for the mutant p53R248Q through suppression of p53-regulated apoptosis-inducing protein 1 in the RA-derived fibroblast-like synoviocyte cell line MH7A." in: Clinical immunology (Orlando, Fla.), Vol. 150, Issue 1, pp. 12-21, (2014) (PubMed).

Yoshida, Monden, Nakamura, Arakawa: "Adenovirus-mediated p53AIP1 gene transfer as a new strategy for treatment of p53-resistant tumors." in: Cancer science, Vol. 95, Issue 1, pp. 91-7, (2004) (PubMed).

Okamura, Arakawa, Tanaka, Nakanishi, Ng, Taya, Monden, Nakamura: "p53DINP1, a p53-inducible gene, regulates p53-dependent apoptosis." in: Molecular cell, Vol. 8, Issue 1, pp. 85-94, (2001) (PubMed).

Oda, Arakawa, Tanaka, Matsuda, Tanikawa, Mori, Nishimori, Tamai, Tokino, Nakamura, Taya: "p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53." in: Cell, Vol. 102, Issue 6, pp. 849-62, (2000) (PubMed).

Synonyms and alternative names related to TP53AIP1

tumor protein p53 regulated apoptosis inducing protein 1 (TP53AIP1), P53AIP1

Protein level used designations for TP53AIP1

  • p53-regulated apoptosis-inducing protein 1
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