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anti-Human HYAL2 Antibodies:
anti-Mouse (Murine) HYAL2 Antibodies:
anti-Rat (Rattus) HYAL2 Antibodies:
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Human Polyclonal HYAL2 Primary Antibody for ELISA, WB - ABIN1327669
Monzón, Manzanares, Schmid, Casalino-Matsuda, Forteza: Hyaluronidase expression and activity is regulated by pro-inflammatory cytokines in human airway epithelial cells. in American journal of respiratory cell and molecular biology 2008
Show all 3 Pubmed References
This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.
hyaluronidase 2 b
, hyaluronoglucosaminidase 2
, hyaluronidase 2
, hyaluronidase 2 a
, PH-20 homolog
, PH20 homolog
, lung carcinoma protein 2
, lysosomal hyaluronidase
, GPI-anchored surface protein
, JSRV envelope protein receptor