TTC3 Products
(Tetratricopeptide Repeat Domain 3 (TTC3))
Categories
E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation\; its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'- polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.
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Featured TTC3 Categories
TTC3 Antibodies
High quality antibodies with extensive validation data.
Recommended TTC3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
Cat. No.
ABIN563278
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA
Validations
- (1)
Cat. No.
ABIN521126
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN7270791
Quantity
100 μL
Datasheet
Datasheet
Recommended TTC3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324013
Quantity
10 μg
Datasheet
Datasheet
Synonyms and alternative names related to TTC3
tetratricopeptide repeat domain 3 (TTC3), tetratricopeptide repeat domain 3 (Ttc3), E3 ubiquitin-protein ligase TTC3 (LOC100562480), 2610202A04Rik, AA409221, D16Ium21, D16Ium21e, DCRR1, mKIAA4119, RNF105, TPRD, TPRDIII, TTC3Protein level used designations for TTC3
- E3 ubiquitin-protein ligase TTC3
- RING finger protein 105
- TPR repeat protein 3
- TPR repeat protein D
- tetratricopeptide repeat protein 3
- mtprd
- tetratricopeptide repeat domain 3
- e3 ubiquitin-protein ligase TTC3-like
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