ULBP1 Products
(UL16 Binding Protein 1 (ULBP1))
Categories
Ligand for the NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP1 to be retained in the ER and cis- Golgi apparatus so that it does not reach the cell surface.
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Featured ULBP1 Categories
ULBP1 Antibodies
High quality antibodies with extensive validation data.
ULBP1 ELISA Kits
Reliable ELISA kits for a wide range of species.
ULBP1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ULBP1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB, FACS
Validations
- (4)
Cat. No.
ABIN7193457
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7174678
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN6149917
Quantity
100 μL
Datasheet
Datasheet
Recommended ULBP1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN2703549
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6385012
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1504058
Quantity
96 tests
Datasheet
Datasheet
Recommended ULBP1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275817
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275818
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125651
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our ULBP1 products
: "Nanoengineered Disruption of Heat Shock Protein 90 Targets Drug-Induced Resistance and Relieves Natural Killer Cell Suppression in Breast Cancer." in: Cancer research, Vol. 80, Issue 23, pp. 5355-5366, (2021) (PubMed).: "Effects of obesity on NK cells in a mouse model of postmenopausal breast cancer." in: Scientific reports, Vol. 10, Issue 1, pp. 20606, (2020) (PubMed).
: "Expression of ligands for activating natural killer cell receptors on cell lines commonly used to assess natural killer cell function." in: BMC immunology, Vol. 20, Issue 1, pp. 8, (2019) (PubMed).
: "NKG2D Regulation of Lung Pathology and Dendritic Cell Function Following Respiratory Syncytial Virus Infection." in: The Journal of infectious diseases, Vol. 218, Issue 11, pp. 1822-1832, (2019) (PubMed).
: "The pharmalogical reactivation of p53 function improves breast tumor cell lysis by granzyme B and NK cells through induction of autophagy." in: Cell death & disease, Vol. 10, Issue 10, pp. 695, (2019) (PubMed).
: "Natural killer cells impede the engraftment of cardiomyocytes derived from induced pluripotent stem cells in syngeneic mouse model." in: Scientific reports, Vol. 9, Issue 1, pp. 10840, (2019) (PubMed).
: "Control of triple-negative breast cancer using ex vivo self-enriched, costimulated NKG2D CAR T cells." in: Journal of hematology & oncology, Vol. 11, Issue 1, pp. 92, (2018) (PubMed).
: "Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 24, Issue 8, pp. 1834-1844, (2018) (PubMed).
: "Immunotherapy of Dual-Function Vector with Both Immunostimulatory and B-Cell Lymphoma 2 (Bcl-2)-Silencing Effects on Gastric Carcinoma." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 23, pp. 1980-1991, (2017) (PubMed).
: "Expression Profiles of Ligands for Activating Natural Killer Cell Receptors on HIV Infected and Uninfected CD4⁺ T Cells." in: Viruses, Vol. 9, Issue 10, (2017) (PubMed).
Synonyms and alternative names related to ULBP1
UL16 binding protein 1 (ULBP1), UL16 binding protein 21 (ULBP21), UL16 binding protein 1 (Ulbp1), NKG2D ligand 1 (LOC100683099), A430108B07Rik, MULT1, RAET1I, ULBP1Protein level used designations for ULBP1
- N2DL-1
- NKG2D ligand 1
- NKG2DL1
- UL16-binding protein 1
- alcan-beta
- retinoic acid early transcript 1I
- UL16 binding protein 1
- UL16-binding protein-like transcript 1
- NK cell receptor ligand
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