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UNC5B Products

(Netrin receptor UNC5B (UNC5B))
This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011].

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Featured UNC5B Categories

UNC5B Antibodies

High quality antibodies with extensive validation data.

UNC5B ELISA Kits

Reliable ELISA kits for a wide range of species.

UNC5B Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended UNC5B Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7161183
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), ICC, IHC (fro), IHC (p)
Validations
  • (2)
Cat. No. ABIN1387790
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN566947
Quantity 100 μg
Datasheet Datasheet

Recommended UNC5B ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971063
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN2748723
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6385076
Quantity 96 tests
Datasheet Datasheet

Recommended UNC5B Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324652
Quantity 10 μg
Datasheet Datasheet
Reactivity Rat
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7321225
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3096243
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our UNC5B products

Choi, de Poot, Lee, Kim, Han, Kim, Finley, Lee: "Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation." in: Nature communications, Vol. 7, pp. 10963, (2016) (PubMed).

Koch, Mathivet, Larrivée, Tong, Kowalski, Pibouin-Fragner, Bouvrée, Stawicki, Nicholes, Rathore, Scales, Luis, del Toro, Freitas, Bréant, Michaud, Corvol, Thomas, Wu, Peale, Watts, Tessier-Lavigne et al.: "Robo4 maintains vessel integrity and inhibits angiogenesis by interacting with UNC5B. ..." in: Developmental cell, Vol. 20, Issue 1, pp. 33-46, (2011) (PubMed).

Tang, Jang, Okada, Chan, Feng, Liu, Luo, Hong, Rama, Xiong, Mehlen, Ye: "Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B." in: Nature cell biology, Vol. 10, Issue 6, pp. 698-706, (2008) (PubMed).

Synonyms and alternative names related to UNC5B

unc-5 netrin receptor B (unc5b), unc-5 netrin receptor B (Unc5b), unc-5 netrin receptor B (UNC5B), unc-5 netrin receptor B L homeolog (unc5b.L), 6330415E02Rik, A630020F16, D10Bwg0792e, p53RDL1, p53rdl1, UNC5B, UNC5C, unc5h2, Unc5h2, UNC5H2

Protein level used designations for UNC5B

  • netrin receptor UNC5B
  • protein unc-5 homolog 2
  • protein unc-5 homolog B
  • unc-5 homolog 2
  • unc5 homolog 2
  • UNC5H2
  • transmembrane receptor Unc5H2
  • p53-regulated receptor for death and life protein 1
  • unc-5 homolog C
  • p53-regulated receptor for death and life
  • unc-5 homolog B (C. elegans)
  • UNC-5 receptor
  • protein Xunc-5
  • protein unc-5 homolog
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