USP15 Products
(Ubiquitin Specific Peptidase 15 (USP15))
Categories
This gene encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. USP enzymes play critical roles in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. The encoded protein associates with the COP9 signalosome, and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 2. [provided by RefSeq, Nov 2011].
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Featured USP15 Categories
USP15 Antibodies
High quality antibodies with extensive validation data.
USP15 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended USP15 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (9)
- (5)
Cat. No.
ABIN564282
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IF, IHC (p)
Validations
- (5)
Cat. No.
ABIN388904
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (4)
Cat. No.
ABIN2855881
Quantity
100 μL
Datasheet
Datasheet
Recommended USP15 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6222175
Quantity
96 tests
Datasheet
Datasheet
Recommended USP15 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125589
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324756
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3096215
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our USP15 products
: "Ubiquitin Specific Peptidase 15 (USP15) suppresses glioblastoma cell growth via stabilization of HECTD1 E3 ligase attenuating WNT pathway activity." in: Oncotarget, Vol. 8, Issue 66, pp. 110490-110502, (2018) (PubMed).: "Ubiquitin-specific Protease 15 Negatively Regulates Virus-induced Type I Interferon Signaling via Catalytically-dependent and -independent Mechanisms." in: Scientific reports, Vol. 5, pp. 11220, (2016) (PubMed).
: "The ubiquitin-specific protease USP15 promotes RIG-I-mediated antiviral signaling by deubiquitylating TRIM25." in: Science signaling, Vol. 7, Issue 307, pp. ra3, (2014) (PubMed).
: "The deubiquitinating enzyme USP5 modulates neuropathic and inflammatory pain by enhancing Cav3.2 channel activity." in: Neuron, Vol. 83, Issue 5, pp. 1144-58, (2014) (PubMed).
: "The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy." in: Human molecular genetics, Vol. 23, Issue 19, pp. 5227-42, (2014) (PubMed).
: "OTUB1 modulates c-IAP1 stability to regulate signalling pathways." in: The EMBO journal, Vol. 32, Issue 8, pp. 1103-14, (2013) (PubMed).
: "Transgenic overexpression of USP15 in the heart induces cardiac remodeling in mice." in: Biochemical and biophysical research communications, Vol. 405, Issue 2, pp. 216-21, (2011) (PubMed).
: "The human COP9 signalosome protects ubiquitin-conjugating enzyme 3 (UBC3/Cdc34) from beta-transducin repeat-containing protein (betaTrCP)-mediated degradation." in: The Journal of biological chemistry, Vol. 285, Issue 23, pp. 17390-7, (2010) (PubMed).
: "The ubiquitin-specific peptidase USP15 regulates human papillomavirus type 16 E6 protein stability." in: Journal of virology, Vol. 83, Issue 17, pp. 8885-92, (2009) (PubMed).
: "USP15 plays an essential role for caspase-3 activation during Paclitaxel-induced apoptosis." in: Biochemical and biophysical research communications, Vol. 388, Issue 2, pp. 366-71, (2009) (PubMed).
Synonyms and alternative names related to USP15
ubiquitin specific peptidase 15 (USP15), universal stress protein UspA (RR_RS05795), ubiquitin carboxyl-terminal hydrolase 15 (LOC100090554), ubiquitin specific peptidase 15 (usp15), ubiquitin specific peptidase 15 (Usp15), 4921514G19Rik, AI327321, E430033I05Rik, Gcap18, mKIAA0529, Ubp109, UNP, UNPH-2, UNPH4, USP15Protein level used designations for USP15
- ubiquitin specific peptidase 15
- universal stress protein
- ubiquitin carboxyl-terminal hydrolase 15-like
- ubiquitin carboxyl-terminal hydrolase 15
- ubiquitin specific protease 15
- ubiquitous nuclear protein
- Deubiquitinating enzyme 15
- Ubiquitin thioesterase 15
- Ubiquitin-specific-processing protease 15
- deubiquitinating enzyme 15
- ubiquitin thioesterase 15
- ubiquitin-specific-processing protease 15
- ubiquitin thiolesterase 15
- granule cell antiserum positive 18
- deubiquitinating enzyme Ubp109
- ubiquitin carboxyl-terminal hydrolase of 109 kDa
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