USP19 Products
(Ubiquitin Specific Peptidase 19 (USP19))
Categories
Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin- dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic- reticulum-associated degradation (ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non- catalytic manner. Plays an important role in 17 beta-estradiol (E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis.
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Featured USP19 Categories
USP19 Antibodies
High quality antibodies with extensive validation data.
Recommended USP19 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (2)
Cat. No.
ABIN6258348
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN7271147
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7188373
Quantity
100 μg
Datasheet
Datasheet
Recommended USP19 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6222182
Quantity
96 tests
Datasheet
Datasheet
Recommended USP19 Proteins
Latest Publications for our USP19 products
: "Ubiquitin-specific protease 19 (USP19) regulates hypoxia-inducible factor 1α (HIF-1α) during hypoxia." in: The Journal of biological chemistry, Vol. 287, Issue 3, pp. 1962-9, (2012) (PubMed).: "The USP19 deubiquitinase regulates the stability of c-IAP1 and c-IAP2." in: The Journal of biological chemistry, Vol. 286, Issue 41, pp. 35380-7, (2011) (PubMed).
: "The ER-resident ubiquitin-specific protease 19 participates in the UPR and rescues ERAD substrates." in: EMBO reports, Vol. 10, Issue 7, pp. 755-61, (2009) (PubMed).
: "High incidence of ubiquitin-like domains in human ubiquitin-specific proteases." in: Proteins, Vol. 69, Issue 1, pp. 1-7, (2007) (PubMed).
Synonyms and alternative names related to USP19
ubiquitin specific peptidase 19 (usp19), ubiquitin specific peptidase 19 (USP19), universal stress protein (RR_RS18085), ubiquitin carboxyl-terminal hydrolase 19 (PTRG_09611), ubiquitin specific peptidase 19 (Usp19), 8430421I07Rik, AI047774, MGC145127, si:dkey-32e6.9, USP19, wu:fc26a05, ZMYND9, Zmynd9Protein level used designations for USP19
- ubiquitin specific peptidase 19
- ubiquitin-specific protease 19
- ubiquitin specific protease 19
- universal stress protein
- ubiquitin carboxyl-terminal hydrolase 19
- ubiquitin carboxyl-terminal hydrolase 19-like
- deubiquitinating enzyme 19
- ubiquitin thioesterase 19
- ubiquitin thiolesterase 19
- ubiquitin-specific-processing protease 19
- zinc finger MYND domain-containing protein 9
- ubiquitin-specific processing protease 19
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