VAMP1/VAMP2 antibody (full length)
The Sheep Polyclonal anti-VAMP1/VAMP2 antibody (ABIN306588) specifically detects VAMP1/VAMP2 in IP and WB.
The antibody is reactive with Human and Rat samples.
Catalog No. ABIN306588
$368.50
Plus shipping costs $50.00
250 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
Quick Overview for VAMP1/VAMP2 antibody (full length) (ABIN306588)
Target
VAMP1/VAMP2
(Vesicle-Associated Membrane Protein 1/2 (Synaptobrevin 1/2) (VAMP1/VAMP2))
Reactivity
Human, Rat
Host
Sheep
Clonality
Polyclonal
Application
Immunoprecipitation (IP), Western Blotting (WB)
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Binding Specificity
- full length
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Purpose
- Sheep anti Human Vesicle Associated Membrane Protein (VAMP 1/2)
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Cross-Reactivity
- Human
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Characteristics
- Vesicle-associated membrane protein 2 is essential for cAMP-regulated exocytosis. VAMP (also know as synaptobrevin) is part of the synaptic vesicle docking and fusion complex and plays a central role in neuroexocytosis. Two VAMP (vesicle-associated membrane protein) isoforms are expressed in the nervous system and are differently distributed among the specialized parts of the tissue. VAMP-1 and -2 are present in all tissues tested, including kidney, adrenal gland, liver, pancreas, thyroid, heart, and smooth muscle. The two isoforms are differentially expressed in various tissues and their level may depend on differentiation. VAMP-1 is restricted to exocrine pancreas and to kidney tubular cells, whereas VAMP-2 is the predominant isoform present in Langerhans islets and in glomerular cells. Both isoforms show a patchy vesicular intracellular distribution in confocal microscopy. Evidence for the importance of neuronal VAMPproteins in the physiology of all cells is indicated.
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Purification
- Ammonium Sulfate Precipitation
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Immunogen
- Full length VAMP1/2 protein
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Isotype
- IgG
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Application Notes
- Applications: Western Blotting, Immunoprecipitation
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- phosphate buffered saline with 0.08 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- VAMP1/VAMP2 (Vesicle-Associated Membrane Protein 1/2 (Synaptobrevin 1/2) (VAMP1/VAMP2))
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Alternative Name
- Vesicle Associated Membrane Protein (VAMP 1/2)
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Background
- Sheep anti vesicle associated membrane protein 1 and 2, VAMP 1 and 2, VAMP1/2, VAMP 1/2, VAMP-1/2, Synaptobrevin 1 and 2
Target
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