ZNF808 Protein (AA 1-903) (His tag)
custom-made
ZNF808
Origin: Human
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target
- ZNF808 (Zinc Finger Protein 808 (ZNF808))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-903
- Origin
- Human
- Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ZNF808 protein is labelled with His tag.
- Purpose
- Predefined custom protein recombinant ZNF808 Protein expressed in mammalian cells.
- Sequence
- MLREEAAQKR KGKESGMALP QGRLTFRDVA IEFSLAEWKF LNPAQRALYR EVMLENYRNL EAVDISSKHM MKEVLSTGQG NREVIHTGTL QRHQSYHIGD FCFQEIEKEI HNIEFQCQED ERNGHEAPTT KIKKLTGSTD QHDHRHAGNK PIKDQLGSSF YSHLPELHIF QIKGEIANQL EKSTSDASSV STSQRISCRP QIHISNNYGN NPLNSSLLPQ KQEVHMREKS FPCNESGKAF NCSSLLRKHQ IPHLGDKQYK CDVCGKLFNH KQYLACHRRC HTGEKPYKCK ECGKSFSYKS SLTCHHRLHT GVKPYKCNEC GKVFRQNSAL VIHKAIHTGE KPYKCNECGK AFNQQSHLSR HQRLHTGVKP YKCKICEKAF ACHSYLANHT RIHSGEKTYK CNECGKAFNH QSSLARHHIL HTGEKPYKCE ECDKVFSQKS TLERHKRIHT GEKPYKCKVC DTAFTCNSQL ARHRRIHTGE KTYKCNECRK TFSRRSSLLC HRRLHSGEKP YKCNQCGNTF RHRASLVYHR RLHTLEKSYK CTVCNKVFMR NSVLAVHTRI HTAKKPYKCN ECGKAFNQQS HLSRHRRLHT GEKPYKCEAC DKVFGQKSAL ESHKRIHTGE KPYRCQVCDT AFTWNSQLAR HTRIHTGEKT YKCNECGKTF SYKSSLVWHR RLHGGEKSYK CKVCDKAFVC RSYVAKHTRI HSGMKPYKCN ECSKTFSNRS SLVCHRRIHS GEKPYKCSEC SKTFSQKATL LCHRRLHSGE KPYKCNDCGN TFRHWSSLVY HRRLHTGEKS YKCTVCDKAF VRNSYLARHI RIHTAEKPYK CNECGKAFNE QSHLSRHHRI HTGEKPYKCE ACDKVFSRKS HLKRHRIIHT GEKPYKCNEC GKAFSDRSTL IHHQAIHGIG KFD Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- ZNF808 (Zinc Finger Protein 808 (ZNF808))
- Alternative Name
- ZNF808
- Background
- Zinc finger protein 808,FUNCTION: Transcriptional repressor that targets mainly transposable elements (PubMed:37973953). Primarily targets the long terminal repeat of endogenous retroviruses classified as MER11 elements which comprise subfamilies A, B and C (PubMed:37973953). May silence transposable elements through the establishment of heterochromatin-associated trimethylation of 'Lys-9' of histone H3 (H3K9me3) (PubMed:37973953). Can also bind to certain gene promoters and other genomic regions (PubMed:37973953). Represses transcription of specific MER11 elements during differentiation toward pancreatic lineages in early pancreas development (PubMed:37973953). By repressing transcription, prevents a liver gene expression program from being aberrantly activated during pancreas differentiation (PubMed:37973953). {ECO:0000269|PubMed:37973953}.
- Molecular Weight
- 104.8 kDa
- UniProt
- Q8N4W9
- AlphaFold
- Q8N4W9
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