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5'-Nucleotidase, Cytosolic III Proteins (NT5C3)

NT5C3 encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. Additionally we are shipping 5'-Nucleotidase, Cytosolic III Antibodies (17) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NT5C3 107569 Q9D020
NT5C3 51251 Q9H0P0
NT5C3 312373  
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Top 5'-Nucleotidase, Cytosolic III Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated 100 μg Log in to see 9 to 19 Days
$1,014.95
Details
HOST_Human Human Un-conjugated 20 μg Log in to see 9 to 11 Days
$785.40
Details
HOST_Escherichia coli (E. coli) Rat Un-conjugated 100 μg Log in to see 9 to 19 Days
$1,014.95
Details

NT5C3 Proteins by Origin and Source

Origin Expressed in
Mouse (Murine)
Human
Rat (Rattus)

More Proteins for 5'-Nucleotidase, Cytosolic III (NT5C3) Interaction Partners

Mouse (Murine) 5'-Nucleotidase, Cytosolic III (NT5C3) interaction partners

  1. polymerization of the Phc2 (show PhC2 Proteins) SAM (show TTN Proteins) domain is required for PRC1 (show PRC1 Proteins) clustering, chromatin condensation and gene silencing.

  2. Phc2 (show PhC2 Proteins) may act as a negative regulator that inhibits the activity of Th cells.

  3. report describes the first X-ray structure of a catalytically inactivated variant of murine cN-III with a natural substrate, uridine 5'-monophosphate, in the active site at 1.74A resolution

  4. functional overlap between Phc2 and Phc1 along with a strict dose-dependent requirement during anterior-posterior (A-P) patterning

Human 5'-Nucleotidase, Cytosolic III (NT5C3) interaction partners

  1. Pyrimidine-5'-nucleotidase (show NT5E Proteins) Campinas is a new mutation (p.R56G) in the NT5C3 gene associated with pyrimidine-5'-nucleotidase (show NT5E Proteins) type I deficiency.

  2. Results show that NT5C3 expression levels were significantly increased in patients with risk allele homozygote.

  3. New missense homozygous mutation (Q270Ter) in the pyrimidine 5' nucleotidase (show NT5E Proteins) type I-related gene in two Indian families with hereditary non-spherocytic hemolytic anemia.

  4. analysis of Drosophila and human 7-methyl GMP (show NT5C2 Proteins)-specific nucleotidases

  5. Data show that PN-I (show NT5C Proteins) shows a higher affinity for oxynucleosides rather than deoxynucleosides, while the opposite is true for PN-II (show APP Proteins).

  6. These data highlight hUMP1/POMP (show POMP Proteins) role in proteasome assembly and further strengthen the prospect of genetic manipulation of the proteasomal system.

  7. In leukoblasts from 82 patients with acute myeloid leukemia (show BCL11A Proteins), various extent and frequency of differential allelic expression in the CDA (show CDA Proteins), DCK (show DCK Proteins), NT5C2 (show NT5C2 Proteins), NT5C3, and TP53 (show TP53 Proteins) genes was observed.

  8. genetic variation in NT5C3 might affect protein function and potentially influence drug response

5'-Nucleotidase, Cytosolic III (NT5C3) Protein Profile

Protein Summary

This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. Mutations in this gene are a cause of hemolytic anemia due to uridine 5-prime monophosphate hydrolase deficiency. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and pseudogenes of this gene are located on the long arm of chromosomes 3 and 4.

Gene names and symbols associated with NT5C3

  • 5'-nucleotidase, cytosolic III (NT5C3)
  • 5'-nucleotidase, cytosolic III (Bm1_56095)
  • 5'-nucleotidase, cytosolic IIIA (nt5c3a)
  • 5'-nucleotidase, cytosolic III (NT5C3A)
  • 5'-nucleotidase, cytosolic III (Nt5c3)
  • 5'-nucleotidase, cytosolic IIIA (NT5C3A)
  • 5'-nucleotidase, cytosolic IIIA (Nt5c3a)
  • polyhomeotic-like 2 (Drosophila) (Phc2)
  • 1600024P05Rik protein
  • 2610206B05Rik protein
  • 3110004A18Rik protein
  • A3galt2 protein
  • AA415044 protein
  • AI842776 protein
  • cN-III protein
  • D4Ertd810e protein
  • D130050K19Rik protein
  • Edr2 protein
  • fb30h07 protein
  • hUMP1 protein
  • lupin protein
  • Mph2 protein
  • Nt5c3 protein
  • Nt5c3a protein
  • Nt5y protein
  • P5'N-1 protein
  • P5N-1 protein
  • p36 protein
  • PN-1 protein
  • PN-I protein
  • POMP protein
  • PSN1 protein
  • PYN1 protein
  • UMPH protein
  • Umph-1 protein
  • UMPH1 protein
  • wu:fb30h07 protein
  • zgc:66117 protein

Protein level used designations for NT5C3

5'-nucleotidase, cytosolic III , cytosolic 5'-nucleotidase 3 , P5'N-1 , P5N-1 , PN-I , cN-III , cytosolic 5'-nucleotidase 3A , cytosolic 5'-nucleotidase III , pyrimidine 5'-nucleotidase 1 , 5'-nucleotidase, pyrimidine , uridine monophosphatase 1 , lupin , uridine 5'-monophosphate hydrolase 1 , early development regulator 2 , early development regulatory protein 2 , polyhomeotic 2 protein , polyhomeotic-like protein 2

GENE ID SPECIES
472343 Pan troglodytes
511858 Bos taurus
6106102 Brugia malayi
100145170 Xenopus (Silurana) tropicalis
395080 Gallus gallus
475277 Canis lupus familiaris
534181 Bos taurus
107569 Mus musculus
51251 Homo sapiens
321720 Danio rerio
494724 Xenopus laevis
312373 Rattus norvegicus
54383 Mus musculus
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