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NT5C3 encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. Additionally we are shipping 5'-Nucleotidase, Cytosolic III Proteins (7) and many more products for this protein.
Showing 10 out of 24 products:
Mouse (Murine) Monoclonal NT5C3 Primary Antibody for IF, IP - ABIN968020
Fisher, Jin, Chamberlin, Morgan: Alternative mechanisms of CAK assembly require an assembly factor or an activating kinase. in Cell 1995
Show all 3 Pubmed References
Human Polyclonal NT5C3 Primary Antibody for IHC, IHC (p) - ABIN4340799
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
polymerization of the Phc2 (show PhC2 Antibodies) SAM (show TTN Antibodies) domain is required for PRC1 (show PRC1 Antibodies) clustering, chromatin condensation and gene silencing.
Phc2 (show PhC2 Antibodies) may act as a negative regulator that inhibits the activity of Th cells.
report describes the first X-ray structure of a catalytically inactivated variant of murine cN-III with a natural substrate, uridine 5'-monophosphate, in the active site at 1.74A resolution
functional overlap between Phc2 (show PhC2 Antibodies) and Phc1 (show PHC1 Antibodies) along with a strict dose-dependent requirement during anterior-posterior (A-P) patterning
reduced expression of transketolase (show TKT Antibodies) in pyrimidine 5'-nucleotidase (show NT5E Antibodies) deficient patients
Pyrimidine-5'-nucleotidase (show NT5E Antibodies) Campinas is a new mutation (p.R56G) in the NT5C3 gene associated with pyrimidine-5'-nucleotidase (show NT5E Antibodies) type I deficiency.
Results show that NT5C3 expression levels were significantly increased in patients with risk allele homozygote.
New missense homozygous mutation (Q270Ter) in the pyrimidine 5' nucleotidase (show NT5E Antibodies) type I-related gene in two Indian families with hereditary non-spherocytic hemolytic anemia.
analysis of Drosophila and human 7-methyl GMP (show NT5C2 Antibodies)-specific nucleotidases
Data show that PN-I (show NT5C Antibodies) shows a higher affinity for oxynucleosides rather than deoxynucleosides, while the opposite is true for PN-II (show APP Antibodies).
These data highlight hUMP1/POMP (show POMP Antibodies) role in proteasome assembly and further strengthen the prospect of genetic manipulation of the proteasomal system.
In leukoblasts from 82 patients with acute myeloid leukemia (show BCL11A Antibodies), various extent and frequency of differential allelic expression in the CDA (show CDA Antibodies), DCK (show DCK Antibodies), NT5C2 (show NT5C2 Antibodies), NT5C3, and TP53 (show TP53 Antibodies) genes was observed.
genetic variation in NT5C3 might affect protein function and potentially influence drug response
This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. Mutations in this gene are a cause of hemolytic anemia due to uridine 5-prime monophosphate hydrolase deficiency. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and pseudogenes of this gene are located on the long arm of chromosomes 3 and 4.
5'-nucleotidase, cytosolic III
, cytosolic 5'-nucleotidase 3
, cytosolic 5'-nucleotidase 3A
, cytosolic 5'-nucleotidase III
, pyrimidine 5'-nucleotidase 1
, 5'-nucleotidase, pyrimidine
, uridine monophosphatase 1
, uridine 5'-monophosphate hydrolase 1
, early development regulator 2
, early development regulatory protein 2
, polyhomeotic 2 protein
, polyhomeotic-like protein 2