anti-ADP-Ribosylation Factor Guanine Nucleotide-Exchange Factor 2 (Brefeldin A-Inhibited) (ARFGEF2) Antibodies

ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking.

list all antibodies Gene Name GeneID UniProt
ARFGEF2 99371  
ARFGEF2 296380  
ARFGEF2 10564 Q9Y6D5
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Top anti-ARFGEF2 Antibodies at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from A549 cells, using ARFGEF2 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of A549 cells, using ARFGEF2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: ARFGEF2 Antibody [NBP1-88607] - Immunohistochemical staining of human small intestine shows distinct cytoplasmic positivity in glandular cells. Western Blot: ARFGEF2 Antibody [NBP1-88607] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10.Lane 2: CACO-2 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, WB 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, ELISA, WB 100 μL Log in to see 7 to 9 Days
$478.50
Details
Human Rabbit Un-conjugated ELISA, IF, WB   100 μg Log in to see 2 to 3 Days
$418.88
Details
Human Rabbit Un-conjugated IF, IHC (p), WB   100 μL Log in to see 7 to 9 Days
$522.50
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Cy5 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Cy7 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

ARFGEF2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , ,


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Top referenced anti-ARFGEF2 Antibodies

  1. Human Polyclonal ARFGEF2 Primary Antibody for ICC, IF - ABIN4281377 : Christis, Munro: The small G protein Arl1 directs the trans-Golgi-specific targeting of the Arf1 exchange factors BIG1 and BIG2. in The Journal of cell biology 2012 (PubMed)

More Antibodies against ARFGEF2 Interaction Partners

Mouse (Murine) ADP-Ribosylation Factor Guanine Nucleotide-Exchange Factor 2 (Brefeldin A-Inhibited) (ARFGEF2) interaction partners

  1. coordinated interactions between actin (through FlnA (show FLNA Antibodies)) and vesicle trafficking (through Big2-Arf (show CDKN2A Antibodies)) direct the assembly and disassembly of membrane protein complexes required for neuronal migration and neuroependymal integrity.

  2. an early acting GEF (show ARHGEF2 Antibodies) (GBF1 (show PTGES2 Antibodies)) activates ARFs that mediate recruitment of late acting GEFs (BIG1 (show CNTN3 Antibodies)/2) to coordinate coating events within the pre-Golgi/Golgi/TGN (show TG Antibodies) continuum.

  3. Big2 inhibition promotes Filamin A (show FLNA Antibodies) phosphorylation, thereby disrupting cell intrinsic neuronal migration.

  4. Results indicate that murine BIG2 is essential for early embryonic development.

Human ADP-Ribosylation Factor Guanine Nucleotide-Exchange Factor 2 (Brefeldin A-Inhibited) (ARFGEF2) interaction partners

  1. Both phospholipase D (show PLD Antibodies) activity and vesicular trafficking were required for effects of BIG1 (show CNTN3 Antibodies) and BIG2 on beta-catenin (show CTNNB1 Antibodies) activation. Levels of PKA-phosphorylated beta-catenin (show CTNNB1 Antibodies) S675 and beta-catenin (show CTNNB1 Antibodies) association with PKA, BIG1 (show CNTN3 Antibodies), and BIG2 were also diminished after BIG1 (show CNTN3 Antibodies)/BIG2 depletion.

  2. Description of a novel ARFGEF2 mutation in five related patients presenting with West syndrome, microcephaly, periventricular heterotopia and thin corpus callosum.

  3. The clinical phenotype associated with mutations in ARFGEF2 is relatively homogeneous in the families report.

  4. Arf guanine nucleotide-exchange factors BIG1 and BIG2 regulate nonmuscle myosin IIA activity by anchoring myosin phosphatase complex.

  5. an early acting GEF (show SLC2A4RG Antibodies) (GBF1 (show GBF1 Antibodies)) activates ARFs that mediate recruitment of late acting GEFs (BIG1 (show CNTN3 Antibodies)/2) to coordinate coating events within the pre-Golgi/Golgi/TGN (show TG Antibodies) continuum.

  6. Brefeldin A-inhibited ADP-ribosylation factor activator BIG2 regulates cell migration via integrin beta1 cycling and actin remodeling.

  7. Up-regulation of ARFGEF2 is associated with the Huntington's disease.

  8. BIG1 (show CNTN3 Antibodies) and BIG2 have roles in endomembrane organization

  9. BIG2 and Exo70 (show EXOC7 Antibodies) interact in trans-Golgi network and centrosomes, as well as in exocyst structures or complexes that move along microtubules to the plasma membrane.

  10. ARFGEF2 mRNA was widely expressed in all cortical layers, especially in the neural precursors of the ventricular and subventricular zones during development, with persistent but diminished expression in adulthood.

ARFGEF2 Antigen Profile

Protein Summary

ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition.

Gene names and symbols associated with ARFGEF2

  • ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) (ARFGEF2) antibody
  • ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) (Arfgef2) antibody
  • AI463430 antibody
  • AW493672 antibody
  • Big2 antibody
  • dJ1164I10.1 antibody
  • E230011G24Rik antibody
  • PVNH2 antibody

Protein level used designations for ARFGEF2

ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) , cytohesin 1-like , brefeldin A-inhibited GEP 2 , brefeldin A-inhibited guanine nucleotide-exchange protein 2 , Brefeldin A-inhibited guanine nucleotide-exchange factor 2

GENE ID SPECIES
419211 Gallus gallus
477256 Canis lupus familiaris
539295 Bos taurus
743923 Pan troglodytes
99371 Mus musculus
296380 Rattus norvegicus
10564 Homo sapiens
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