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Transcription factor that specifically activates the expression of the CD40 receptor and its ligand CD40L/CD154, two cell surface molecules on lymphocytes that are critical for antigen-dependent-B-cell development. Additionally we are shipping AKNA Antibodies (7) and AKNA Kits (2) and many more products for this protein.
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Results support the hypothesis that akna is a cervical cancer susceptibility genetic factor and suggest that akna transcriptional regulation has a role in the disease; identified an association between high akna expression levels and cervical cancer and squamous intraepithelial lesion, but its direction differs in each disease stage.
significantly decreased expression of CD18 (show ITGB2 Proteins) and AKNA suggests a role for both proteins in the pathogenesis of Vogt-Koyanagi-Harada syndrome
Data indicate that AKNA appears to be an important genetic factor associated with the risk cervical cancer.
AKNA expresses multiple transcripts and protein isoforms as a result of alternative promoter usage, splicing, and polyadenylation.
targeted deletions of mouse AKNA, a hypothetical AT-hook-like transcription factor, sensitize mice to pathogen-induced inflammation and cause sudden neonatal death
Transcription factor that specifically activates the expression of the CD40 receptor and its ligand CD40L/CD154, two cell surface molecules on lymphocytes that are critical for antigen-dependent-B-cell development. Binds to A/T-rich promoters.
AT-hook-containing transcription factor
, AT-hook transcription factor
, AKNA transcript F2
, AT-hook transcription factor AKNA