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anti-ATPase, Cu++ Transporting, beta Polypeptide (ATP7B) Antibodies

ATP7B is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. Additionally we are shipping ATP7B Proteins (10) and ATP7B Kits (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ATP7B 540 P35670
ATP7B 11979 Q64446
ATP7B 24218  
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Top anti-ATP7B Antibodies at antibodies-online.com

Showing 10 out of 129 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged ATP7B is approximately 0.3 ... 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human testis tissue... Immunofluorescence analysis of HeLa cells, using ATP7B Antibody. The p... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of ATP7B antibody (C-term) (ABIN390398) in HepG2... ATP7B Antibody (C-term) (ABIN390398) IHC analysis in formalin fixed an... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged ATP7B is approximately 0.3n... ATP7B monoclonal antibody (M01), clone 3E10. Western Blot analysis of ... 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA Anti-ATP7B antibody IHC staining of human lung, respiratory epithelium... 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-ATP7b antibody, IHC(P) IHC(P): Mouse Liver Tissue Anti-ATP7b antibody, IHC(P) IHC(P): Rat Liver Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Mouse Un-conjugated IHC, WB Immunoblot on rat brain membranes. 100 μg Log in to see 2 to 3 Days
$438.73
Details
Human Rabbit FITC IF (p) Mouse hepatocytes probed with Rabbit Anti-ATP7B Polyclonal Antibody, F... 100 μL Log in to see 14 to 21 Days
$357.50
Details
Cow Mouse FITC FACS   0.1 mg Log in to see 6 to 8 Days
$632.50
Details

ATP7B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
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Mouse (Murine) , , , ,
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Rat (Rattus) , , , ,
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Top referenced anti-ATP7B Antibodies

  1. Human Monoclonal ATP7B Primary Antibody for ELISA, WB - ABIN393414 : Singleton, McInnes, Cater, Winnall, McKirdy, Yu, Taylor, Ke, Richardson, Mercer, La Fontaine: Role of glutaredoxin1 and glutathione in regulating the activity of the copper-transporting P-type ATPases, ATP7A and ATP7B. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN393414

  2. Human Polyclonal ATP7B Primary Antibody for EIA, WB - ABIN452773 : Martinez-Balibrea, Martínez-Cardús, Musul��n, Ginés, Manzano, Aranda, Plasencia, Neamati, Abad: Increased levels of copper efflux transporter ATP7B are associated with poor outcome in colorectal cancer patients receiving oxaliplatin-based chemotherapy. in International journal of cancer. Journal international du cancer 2009 (PubMed)

  3. Human Monoclonal ATP7B Primary Antibody for ELISA, WB - ABIN560009 : Ansede, Wright, St Claire, Hart, Gefroh, Brouwer: Characterization of sandwich-cultured hepatocytes as an in vitro model to assess the hepatobiliary disposition of copper. in Drug metabolism and disposition: the biological fate of chemicals 2009 (PubMed)

  4. Human Polyclonal ATP7B Primary Antibody for IF, IHC - ABIN1533712 : Dunham, Matthews, Burton, Ashurst, Howe, Ashcroft, Beare, Burford, Hunt, Griffiths-Jones, Jones, Keenan, Oliver, Scott, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey et al.: The DNA sequence and analysis of human chromosome 13. ... in Nature 2004 (PubMed)

More Antibodies against ATP7B Interaction Partners

Cow (Bovine) ATPase, Cu++ Transporting, beta Polypeptide (ATP7B) interaction partners

  1. Data show that CD4 (show CD4 Antibodies)(+) and WC1(+) gammadelta T-cells were induced to produce IL-17 (show IL17A Antibodies) termed Th17 and gammadelta17 cells.

  2. The endocytosis and signaling of the gamma-delta T cell coreceptor WC1 are regulated by a dileucine motif.

  3. WC1 is a hybrid gamma-delta TCR coreceptor and pattern recognition receptor for pathogenic bacteria.

  4. Identification of differences in the signal transduction through the endodomains of WC1 contributes to understanding the functional role of the WC1 coreceptors in the gammadelta T cell responses.

  5. Specific receptors in the WC1 family directly participate in Leptospira recognition and/or activation of gamma-delta T cells.

  6. These findings revealed that despite the existence of a distinct bovine CD4 (show CD4 Antibodies)(+)CD25 (show IL2RA Antibodies)(high) T cell population, which showed Foxp3 (show FOXP3 Antibodies) transcription/expression, natural regulatory activity did not reside in this cell population

  7. Sudies demonstrate that WC1 molecules are encoded by a large, multi-gene family whose transcripts undergo extensive alternative splicing.

Human ATPase, Cu++ Transporting, beta Polypeptide (ATP7B) interaction partners

  1. Extrinsic expressing WT ATP7B reduced CuCl2-induced copper accumulation and enhanced cellular copper tolerance by accelerating copper excretion, which was selectively compromised by R778L and P992L mutations.

  2. Metal-dependent movement of the first four metal-binding domains in ATP7B may be a trigger that initiates the overall catalytic cycle.

  3. Nine out of the thirty-two pediatric Turkish WD patients had no mutations in the ATP7B gene.

  4. Novel mutation of the ATP7B gene was found in Chinese families with pre-symptomatic Wilson's disease.

  5. Wilson disease causing p.T788I, p.V1036I and p.R1038G-fsX83 mutations lead to functional deficiency in ATP7B protein.

  6. The present results demonstrate the design and evaluation of a low-density microarray for the detection of 62 mutations in ATP7B gene, and show that a microarray based approach can be cost-effective for detecting a large number of mutations simultaneously

  7. Screening for the two exons 14 and 18 of the ATP7B gene is important in Egyptian patients especially in suspected patients without hepatic manifestations.

  8. The ATP7B gene testing for the boy, his sister, and their parents detected two novel missense mutations in the boy and his sister, i.e., compound heterozygous mutations in exon 7 and exon 13

  9. The detection of new mutations in the ATP7B gene can aid in genetic counseling and clinical or/prenatal diagnosis.

  10. Identification of mutations and polymorphisms of the ATP7B gene which may contribute to the pathogenesis of Wilson disease.

Mouse (Murine) ATPase, Cu++ Transporting, beta Polypeptide (ATP7B) interaction partners

  1. Data indicate that the copper-transporting ATPase (show DNAH8 Antibodies) gene (Atp7b) knockout mice showed a drastic, time-dependent accumulation of hepatic copper.

  2. The aim of this study was to identify copper disturbances according to various brain compartments and further dissect the causal relationship between copper storage and neuronal damage using Atp7b(-/-) mice.

  3. DKWSLLL sequence is essential for ATP7b sorting at the TGN (show TG Antibodies), transport from the TGN (show TG Antibodies) to the PM, endocytosis, and recycling to the TGN (show TG Antibodies) and PM.

  4. Ligand-activated nuclear receptors FXR/NR1H4 (show NR1H4 Antibodies) and GR/NR3C1 (show NR3C1 Antibodies) and nuclear receptor interacting partners are less abundant in Atp7b(-/-) hepatocyte nuclei.

  5. By performing dynamic PET, authors obtained the first real-time measurements of 64Cu distribution in the organs or tissues of Atp7b -/- mice.

  6. Clusterin (show CLU Antibodies) and COMMD1 (show COMMD1 Antibodies) independently regulate degradation of the mammalian copper ATPases ATP7A (show ATP7A Antibodies) and ATP7B.

  7. Neuroinflammatory and behavioural changes in the Atp7B mutant mouse model of Wilson's disease.

  8. The Jackson toxic milk mouse as a model for copper loading

  9. Both Atp7a (show ATP7A Antibodies) and Atp7b are expressed in glomeruli; however, Atp7b is also seen in the kidney medulla suggesting that glomeruli are responsible for regulating copper levels in the filtrate

  10. Mice homozygous for the recessive txJ mutation examined at 6 months of age exhibited a reduced number of amyloid plaques and diminished plasma Abeta (show APP Antibodies) levels. Homozygosity for txJ increased survival and lowered endogenous CNS Abeta (show APP Antibodies).

Pig (Porcine) ATPase, Cu++ Transporting, beta Polypeptide (ATP7B) interaction partners

  1. A copper-dependent ATPase (show DNAH8 Antibodies) hydrolysis in a native Golgi-enriched preparation from liver, was characterized.

ATP7B Antigen Profile

Protein Summary

This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).

Gene names and symbols associated with ATP7B

  • ATPase, Cu++ transporting, beta polypeptide (ATP7B) antibody
  • ATPase, Cu++ transporting, beta polypeptide (atp7b) antibody
  • ATPase, Cu++ transporting, beta polypeptide (Wilson disease) (atp7b) antibody
  • ATPase, Cu++ transporting, beta polypeptide (LOC100344865) antibody
  • ATPase, Cu++ transporting, beta polypeptide (Atp7b) antibody
  • BoWC1.1 (WC1) antibody
  • CD163 molecule-like 1 (CD163L1) antibody
  • Atp7a antibody
  • ATP7B antibody
  • Hts antibody
  • PINA antibody
  • PWD antibody
  • tx antibody
  • WC1 antibody
  • Wd antibody
  • WND antibody

Protein level used designations for ATP7B

ATPase, Cu++ transporting, beta polypeptide , copper-transporting ATPase beta subunit , ATPase, Cu++ transporting, beta polypeptide (Wilson disease) , Wilson's disease protein , copper-transporting ATPase , copper-transporting ATPase 2 , ATP7B-like , copper-transporting ATPase 2-like , ATPase, Cu(2+)- transporting, beta polypeptide , Wilson disease-associated protein , copper pump 2 , Wilson protein , toxic milk , wilson disease-associated protein homolog , ATPase, Cu++ transporting, beta polypeptide (same as Wilson disease) , PINA gene, promoter , pineal night-specific ATPase , ATPase, Cu(2+)-transporting, beta polypeptide , ATPase 7B protein , scavenger receptor cysteine-rich type 1 protein M160 , scavenger-receptor protein

GENE ID SPECIES
518075 Bos taurus
442967 Canis lupus familiaris
476903 Canis lupus familiaris
556499 Danio rerio
571325 Danio rerio
592143 Strongylocentrotus purpuratus
713781 Macaca mulatta
100344865 Oryctolagus cuniculus
100469748 Ailuropoda melanoleuca
100497797 Xenopus (Silurana) tropicalis
100028163 Monodelphis domestica
100082671 Ornithorhynchus anatinus
100052751 Equus caballus
100541545 Meleagris gallopavo
100558446 Anolis carolinensis
540 Homo sapiens
11979 Mus musculus
24218 Rattus norvegicus
418879 Gallus gallus
100049684 Sus scrofa
443046 Ovis aries
783109 Bos taurus
100144477 Sus scrofa
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