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Abhydrolase Domain Containing 5 (ABHD5) ELISA Kits

The protein encoded by ABHD5 belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. Additionally we are shipping ABHD5 Antibodies (68) and ABHD5 Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ABHD5 51099 Q8WTS1
Anti-Mouse ABHD5 ABHD5 67469 Q9DBL9
ABHD5 316122 Q6QA69
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Top ABHD5 ELISA Kits at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Chicken 0.025ng/ml 0.04-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$1,081.67
Details
Rat
96 Tests Log in to see 16 to 21 Days
$999.43
Details
Human
96 Tests Log in to see 16 to 21 Days
$999.43
Details

More ELISA Kits for ABHD5 Interaction Partners

Human Abhydrolase Domain Containing 5 (ABHD5) interaction partners

  1. Authors show that rat ATGL (show PNPLA2 ELISA Kits), coactivated by rat CGI-58, efficiently hydrolyzes triglycerides and retinyl ester.

  2. novel ABHD5 truncating variant in a twenty nine month old female child, who presented with icthyosiform erythroderma.

  3. simultaneous tryptophan alanine permutations in both arms abolish localization and activity of CGI-58 as opposed to tryptophan substitutions that occur in only one arm.

  4. this study presents clinical and molecular data of four affected relatives with Chanarin-Dorfman syndrome homozygous for a N209X mutation in ABHD5, and provides a short review by comparing patients with N209X homozygous mutations to patients with other ABHD5 mutations.

  5. PLIN5 (show PLIN5 ELISA Kits) was significantly colocated with ATGL (show PNPLA2 ELISA Kits), mitochondria and CGI-58, indicating a close association between the key lipolytic effectors in resting skeletal muscle.

  6. -mediated phosphorylation of CGI-58 is required for dispersion of CGI-58 from perilipin (show PLIN1 ELISA Kits) 1A-coated lipid droplets

  7. Abhd5 expression falls substantially and correlates negatively with malignant features in human colorectal cancer.

  8. Findings indicate a molecular mechanisms by which lysophosphatidic acid acyltransferase (show MBOAT2 ELISA Kits) CGI-58 regulates lipid homeostasis.

  9. ABHD5, PGRMC1 (show PGRMC1 ELISA Kits) and SQS (show FDFT1 ELISA Kits) are novel markers for sebaceous carcinoma and can reliably distinguish sebaceous neoplasms from non-sebaceous tumors, specifically BCC with clear cell features.

  10. A report of two Chanarin-Dorfman syndrome sisters with severe steatohepatitis and decompensated cirrhosis due to steatohepatitis in whom the clinical presentation developed due to a new mutation in ABHD5 gene.

Mouse (Murine) Abhydrolase Domain Containing 5 (ABHD5) interaction partners

  1. Here, we identify synthetic ligands that release ABHD5 from PLIN1 (show PLIN1 ELISA Kits) or PLIN5 (show PLIN5 ELISA Kits) without PKA activation and rapidly activate adipocyte and muscle lipolysis.

  2. we identify adipocyte-type fatty acid-binding protein (A-Fabp (show FABP4 ELISA Kits)) and other members of the fatty acid-binding protein (Fabp (show FABP ELISA Kits)) family as interaction partners of Cgi-58.

  3. Data (including data from studies in atherosclerotic knockout mice) suggest CGI58-deficient macrophages store-up triglyceride-rich droplets and have reduced phagocytic capacity, comparable to Atgl- (adipose triglyceride lipase (show PNPLA2 ELISA Kits)-)deficient macrophages.

  4. -mediated phosphorylation of CGI-58 is required for dispersion of CGI-58 from perilipin (show PLIN1 ELISA Kits) 1A-coated lipid droplets

  5. Muscle CGI-58 deficiency causes cardiac dysfunction and fat deposition in oxidative muscles but induces a series of favorable metabolic changes in mice fed a high-fat diet.

  6. intestinal CGI-58 is required for efficient postprandial lipoprotein-TG secretion and for maintaining hepatic and plasma lipid homeostasis.

  7. CGI-58 transgenic/ApoE (show APOE ELISA Kits)-/- mice exhibited an anti-atherosclerosis phenotype compared with wild type (WT) controls (CGI-58 WT/ApoE (show APOE ELISA Kits)-/-), illustrated by less plaque area in aortic roots.

  8. The anti-lipolytic activity of the HCV core protein alters ATGL (show PNPLA2 ELISA Kits) binding to CGI-58 and enhances the association of both proteins with lipid droplets.

  9. These data thus identified a vicious cycle (IL-1beta (show IL1B ELISA Kits)-SOCS3 (show SOCS3 ELISA Kits)-FOXO1 (show FOXO1 ELISA Kits)-IL-1beta (show IL1B ELISA Kits)) that amplifies IL-1beta (show IL1B ELISA Kits) secretion and is initiated by CGI-58 deficiency-induced activation of the NLRP3 (show NLRP3 ELISA Kits) inflammasome in macrophages.

  10. Perilipins 2 and 3 lack a carboxy-terminal domain present in perilipin 1 (show PLIN1 ELISA Kits) involved in sequestering ABHD5 and suppressing basal lipolysis.

Pig (Porcine) Abhydrolase Domain Containing 5 (ABHD5) interaction partners

  1. These findings suggest that CGI-58 may be a new target for enhancing the quality of pork products as well as offering the potential of CGI-58 for human obesity treatment.

ABHD5 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in this gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation.

Gene names and symbols associated with ABHD5

  • abhydrolase domain containing 5 (ABHD5) antibody
  • abhydrolase domain containing 5 (abhd5) antibody
  • abhydrolase domain containing 5a (abhd5a) antibody
  • abhydrolase domain containing 5 (LOC100229229) antibody
  • abhydrolase domain containing 5 (LOC100350162) antibody
  • abhydrolase domain containing 5 (Abhd5) antibody
  • 1300003D03Rik antibody
  • 2010002J10Rik antibody
  • abhd5 antibody
  • CDS antibody
  • CGI-58 antibody
  • CGI58 antibody
  • IECN2 antibody
  • IECN5 antibody
  • NCIE2 antibody

Protein level used designations for ABHD5

abhydrolase domain containing 5 , CGI58 protein , 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 , abhydrolase domain-containing protein 5 , lipid droplet-binding protein CGI-58 , alpha/beta hydrolase domain-containing 5 , lipid droplet binding protein , Abhydrolase domain-containing protein 5

GENE ID SPECIES
460303 Pan troglodytes
549643 Xenopus (Silurana) tropicalis
566493 Danio rerio
100066775 Equus caballus
100229229 Taeniopygia guttata
100350162 Oryctolagus cuniculus
100125355 Ovis aries
51099 Homo sapiens
67469 Mus musculus
485570 Canis lupus familiaris
497624 Sus scrofa
535588 Bos taurus
316122 Rattus norvegicus
446400 Xenopus laevis
420673 Gallus gallus
100174407 Pongo abelii
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