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Acyl-CoA Dehydrogenase, Long Chain Proteins (ACADL)

The protein encoded by ACADL belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. Additionally we are shipping ACADL Antibodies (97) and ACADL Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ACADL 33 P28330
ACADL 25287 P15650
ACADL 11363 P51174
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Top ACADL Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,107.50
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$3,107.50
Details

ACADL Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Rat (Rattus)

Mouse (Murine)

Top referenced ACADL Proteins

  1. Human ACADL Protein expressed in Escherichia coli (E. coli) - ABIN667975 : Maher, Mohsen, Vockley, Tarnopolsky: Low expression of long-chain acyl-CoA dehydrogenase in human skeletal muscle. in Molecular genetics and metabolism 2010 (PubMed)
    Show all 2 references for ABIN667975

More Proteins for Acyl-CoA Dehydrogenase, Long Chain (ACADL) Interaction Partners

Human Acyl-CoA Dehydrogenase, Long Chain (ACADL) interaction partners

  1. the fatty acid oxidation pathway and LCAD are factors contributing to the pathophysiology of pulmonary disease

  2. Sirtuin 3 (SIRT3 (show SIRT3 Proteins)) protein regulates long-chain acyl-CoA dehydrogenase by deacetylating conserved lysines near the active site.

  3. LCAD is minimally expressed in human skeletal muscle and likely does not play a significant role in long-chain fatty acid oxidation.

Mouse (Murine) Acyl-CoA Dehydrogenase, Long Chain (ACADL) interaction partners

  1. SIRT3 (show SIRT3 Proteins) may play an essential role in attenuating lipid accumulation in the heart through the deacetylation of LCAD

  2. Carnitine supplementation lowered myocardial triglycerides, normalizing myocardial triglycerides levels in LCAD Knock-out mice.

  3. LCAD KO mice are ineffective in maintaining metabolic homeostasis during fasting, which is reflected by an impaired myocardial energy status in fasted LCAD KO mice.

  4. the fatty acid oxidation pathway and LCAD are factors contributing to the pathophysiology of pulmonary disease

  5. Sirtuin 3 (SIRT3 (show SIRT3 Proteins)) protein regulates long-chain acyl-CoA dehydrogenase by deacetylating conserved lysines near the active site.

  6. mice with an inherited deficiency of very long-chain acyl-CoA dehydrogenase (VLCAD (show ACADVL Proteins)), were protected from high-fat diet-induced obesity and liver and muscle insulin (show INS Proteins) resistance.

  7. LCAD is deacetylated in wild-type mice under fasted conditions and by SIRT3 (show SIRT3 Proteins) in vitro and in vivo; hyperacetylation of LCAD reduces its enzymatic activity

  8. These data demonstrate that primary defects in mitochondrial fatty acid oxidation capacity can lead to diacylglycerol accumulation, PKCepsilon (show PRKCE Proteins) activation, and hepatic insulin (show INS Proteins) resistance.

  9. Novel candidate genes in T1D CD55 (show CD55 Proteins) and Acadl were identified.

  10. substantial cardiac hypertrophy in LCAD-deficient mice

ACADL Protein Profile

Protein Summary

The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia.

Gene names and symbols associated with ACADL

  • acyl-Coenzyme A dehydrogenase, long chain (acadl)
  • acyl-CoA dehydrogenase, long chain (ACADL)
  • acyl-CoA dehydrogenase, long chain (acadl)
  • acyl-CoA dehydrogenase, long chain (Acadl)
  • acyl-Coenzyme A dehydrogenase, long-chain (Acadl)
  • AA960361 protein
  • ACAD4 protein
  • ACOADA protein
  • AU018452 protein
  • C79855 protein
  • LCAD protein
  • zgc:55656 protein

Protein level used designations for ACADL

LCAD , long-chain specific acyl-CoA dehydrogenase, mitochondrial , acyl-Coenzyme A dehydrogenase, long chain , long-chain acyl-CoA dehydrogenase , Acyl Coenzyme A dehydrogenase, long chain , LCAD long chain acyl-CoA dehydrogenase , acetyl-Coenzyme A dehydrogenase, long-chain , acyl-Coenzyme A dehydrogenase, long-chain

GENE ID SPECIES
394156 Danio rerio
459914 Pan troglodytes
734116 Xenopus (Silurana) tropicalis
33 Homo sapiens
396931 Sus scrofa
614508 Bos taurus
25287 Rattus norvegicus
446669 Xenopus laevis
424005 Gallus gallus
478895 Canis lupus familiaris
11363 Mus musculus
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