You are viewing an incomplete version of our website. Please click to reload the website as full version.

Acyl-CoA Synthetase Long-Chain Family Member 1 Proteins (Acsl1)

The protein encoded by Acsl1 is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Additionally we are shipping Acyl-CoA Synthetase Long-Chain Family Member 1 Antibodies (63) and Acyl-CoA Synthetase Long-Chain Family Member 1 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Acsl1 2180 P33121
Acsl1 14081 P41216
Acsl1 25288 P18163
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Acyl-CoA Synthetase Long-Chain Family Member 1 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,895.83
Details

Acsl1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,
Rat (Rattus)

More Proteins for Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1) Interaction Partners

Human Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1) interaction partners

  1. SRE motif in ACSL1 is essential for SREBP2 (show SREBF2 Proteins)-mediated activation of C-ACSL1 gene transcription.

  2. ACSL1 is a programmable mediator of insulin (show INS Proteins) sensitivity and cellular lipid content.

  3. the cell surface protein (show CD28 Proteins) CD36 (show CD36 Proteins)/FAT directly facilitates fatty acid transport across the plasma membrane, whereas the intracellular acyl-CoA (show GNPAT Proteins) synthetases FATP4 (show SLC27A4 Proteins) and ACSL1 enhance fatty acid uptake indirectly by metabolic trapping

  4. Data indicate that expression of miR-205 is negatively related to that of ACSL1 in clinical hepatocellular carcinoma (HCC) tissues.

  5. INSR rs1366600, ACSL1 rs2292899 and FABP2 rs11724758 could influence the susceptibility to type 2 diabetes in Chinese Han population, most likely through their effects on the specific miRNA-binding sites.

  6. long-chain acyl-CoA synthetase 1 has a role in eicosapentaenoic acid suppression of palmitate-induced cytokine production

  7. Findings suggest that the ACSL1 gene polymorphism rs6552828 is not associated with elite endurance athletic status in Caucasians, yet a marginal association seems to exist for the Chinese (Han) male population.

  8. Data show that ACSL1 rs9997745 polymorphism influences metabolic syndrome risk, most likely via disturbances in fatty acid metabolism, which was modulated by dietary fat consumption, particularly PUFA intake, suggesting novel gene-nutrient interactions.

  9. Based on homology, two new isoforms for ACSL1 were predicted and characterized, one represented a switch of the Phe- to the Tyr (show TYR Proteins)-Gate domain motif, the other resulted from the exclusion of both.

Pig (Porcine) Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1) interaction partners

  1. The pig ACSL1 gene expresses differently in different tissues and pig breeds.

  2. Authors have sequenced 3,013 bp of the pig acyl coenzyme A (show SOAT1 Proteins) long-chain synthetase 1 (ACSL1) gene.

Cow (Bovine) Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1) interaction partners

  1. The initial QTL analysis suggested the ACSL1 gene as a candidate gene for fatty acid composition in bovine skeletal muscle; subsequent analyses indicate that ACSL1 or a gene in close proximity plays a functional role in the lipid composition of beef.

  2. The results of this study suggest that suggest that SLC27A6, ACSL1, FABP3 (show FABP3 Proteins), AGPAT6 (show AGPAT6 Proteins), and LPIN1 (show LPIN1 Proteins) coordinately regulate the channeling of fatty acids toward copious milk fat synthesis in bovine mammary.

Mouse (Murine) Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1) interaction partners

  1. Data (including data from studies in cell line from knockout mice) suggest high incorporation of long-chain fatty acids, partly mediated by Acsl1, plays role in supply of octanoic acid for ghrelin (show GHRL Proteins) acylation/lipoylation in ghrelin (show GHRL Proteins)-producing cells.

  2. Acyl-CoA synthetase 1 deficiency alters cardiolipin species and impairs mitochondrial function

  3. ACSL1 is a programmable mediator of insulin (show INS Proteins) sensitivity and cellular lipid content.

  4. long-chain acyl-CoA synthetase (show Acsl3 Proteins) isoform 1 (ACSL1) deficiency in the heart activated mTORC1, thereby inhibiting autophagy and increasing the number of damaged mitochondria.

  5. Acsl1(M-/-) mice were more insulin (show INS Proteins) sensitive, and, during an overnight fast, their respiratory exchange ratio was higher, indicating greater glucose use and during endurance exercise, Acsl1(M-/-) mice ran only 48% as far as controls.

  6. These data indicate that Acsl1-deficiency causes diastolic dysfunction and that mTOR (show FRAP1 Proteins) activation is linked to the development of cardiac hypertrophy in Acsl1(H-/-) mice.

  7. Data indicate that the expression levels of ACSL1 and its metabolite triglyceride levels were remarkably increased in hepatitis B virus X protein (HBx)-induced liver cancer tissues from the HBx transgenic mice model.

  8. Increases understanding of the role of ACSL1 in monocytes/macrophages in inflammation and diabetes-accelerated atherosclerosis offers hope for new treatment to combat diabetic vascular disease[review]

  9. Acyl-CoA synthetase 1 is induced by Gram-negative bacteria and lipopolysaccharide and is required for phospholipid turnover in stimulated macrophages

  10. Endothelial ACSL1 is not required for inflammatory and apoptotic effects of a saturated fatty acid-rich environment.

Arabidopsis thaliana Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1) interaction partners

  1. The combined inactivation of LACS1 and LACS4 (show ACSL4 Proteins) in Arabidopsis resulted in conditional pollen sterility and impaired wax biosynthesis.

  2. LACS1 is localized in the ER and functionally overlaps with LACS9 to supply acyl-CoAs for TAG biosynthesis.

  3. Both ABA and LRD2 control root system architecture in the presence or absence of osmotic stress in A. thaliana. [LRD2]

  4. lacs1 lacs2 double-mutant plants displayed pleiotropic phenotypes including organ fusion, abnormal flower development and reduced seed set.

  5. LACS1 is a functionally novel acyl-CoA synthetase that preferentially modifies both VLCFAs for wax synthesis and long-chain (C16) fatty acids for cutin synthesis.

Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1) Protein Profile

Protein Summary

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation.

Gene names and symbols associated with Acsl1

  • acyl-CoA synthetase long-chain family member 1 (acsl1)
  • acyl-CoA synthetase long-chain family member 1 (ACSL1)
  • long-chain-fatty-acid-CoA ligase 1 (PGTG_13183)
  • acyl-CoA synthetase long-chain family member 1 (Acsl1)
  • long chain acyl-CoA synthetase 1 (LACS1)
  • long-chain acyl-CoA synthetase 2 (LACS2)
  • Acas protein
  • Acas1 protein
  • ACS protein
  • ACS1 protein
  • CER8 protein
  • COAA protein
  • ECERIFERUM 8 protein
  • F13F21.14 protein
  • F13F21_14 protein
  • FACL1 protein
  • Facl2 protein
  • FACS protein
  • LACS protein
  • LACS1 protein
  • LACS2 protein
  • LATERAL ROOT DEVELOPMENT 2 protein
  • LONG-CHAIN ACYL-COA SYNTHASE 1 protein
  • long-chain acyl-CoA synthetase 2 protein
  • LRD2 protein
  • T8I13.8 protein
  • zgc:110081 protein

Protein level used designations for Acsl1

long-chain-fatty-acid-CoA ligase 1 , LACS 1 , LACS 2 , acyl-CoA synthetase 1 , fatty-acid-Coenzyme A ligase, long-chain 1 , fatty-acid-Coenzyme A ligase, long-chain 2 , lignoceroyl-CoA synthase , long-chain acyl-CoA synthetase 1 , long-chain acyl-CoA synthetase 2 , long-chain fatty acid-CoA ligase 2 , long-chain fatty-acid-coenzyme A ligase 1 , long-chain-fatty-acid--CoA ligase 1 , palmitoyl-CoA ligase 1 , palmitoyl-CoA ligase 2 , paltimoyl-CoA ligase 1 , acyl coenzyme A synthetase long-chain 1 , fatty acid coenzyme A ligase long-chain 2 , acetate-CoA ligase , acetyl-CoA synthetase , acetyl-Coenzyme A synthetase 1 (ADP forming) , fatty acid Coenzyme A ligase, long chain 2 , Acyl CoA synthetase, long chain , long-chain-fatty-acid--CoA ligase, liver isozyme , palmitoyl-CoA ligase

GENE ID SPECIES
555308 Danio rerio
100057925 Equus caballus
10541388 Puccinia graminis f. sp. tritici CRL 75-36-700-3
2180 Homo sapiens
475631 Canis lupus familiaris
448982 Sus scrofa
537161 Bos taurus
14081 Mus musculus
25288 Rattus norvegicus
422547 Gallus gallus
100135469 Cavia porcellus
819337 Arabidopsis thaliana
841367 Arabidopsis thaliana
Selected quality suppliers for Acyl-CoA Synthetase Long-Chain Family Member 1 Proteins (Acsl1)
Did you look for something else?