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Adrenergic, beta-1-, Receptor Proteins (ADRB1)

The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Additionally we are shipping Adrenergic, beta-1-, Receptor Antibodies (47) and Adrenergic, beta-1-, Receptor Kits (23) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ADRB1 11554 P34971
ADRB1 153 P08588
Rat ADRB1 ADRB1 24925 P18090
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Top Adrenergic, beta-1-, Receptor Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details

ADRB1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Adrenergic, beta-1-, Receptor (ADRB1) Interaction Partners

Zebrafish Adrenergic, beta-1-, Receptor (ADRB1) interaction partners

  1. Zebrafish larvae lacking beta1AR expression by morpholino knockdown displayed lower heart rates than control fish, whereas larvae deficient in both beta2aAR and beta2bAR expression exhibited significantly higher heart rates than controls.

Mouse (Murine) Adrenergic, beta-1-, Receptor (ADRB1) interaction partners

  1. Galphai2 (show GNAI2 Proteins) deficiency combined with cardiac beta1-adrenoceptor overexpression strongly impaired survival and cardiac function, leading to dilated cardiomyopathy.

  2. Knockout of the C5aR1 (show C5AR1 Proteins) attenuated the effect of beta1-AR in the heart, suggesting an association between the beta1-AR and C5aR1 (show C5AR1 Proteins), although further investigation is required to determine if this is a direct or causal association

  3. Partial gap junction uncoupling increased propensity and amplitude of Ca(2 (show CA2 Proteins)+) alternans, and made them more sensitive to reversal by beta-AR activation, as in isolated myocytes.

  4. These data reveal a novel interplay between the E2F pathway, beta2-adrenergic/PKA/PDE4D, and ERK/c-Src axis in fine tuning the pathological hypertrophic growth response.

  5. Myocardial adrenergic receptor beta 1 preferentially associates with AC5 (show ADCY5 Proteins).

  6. role of beta-ARs (show SLURP1 Proteins) in early muscle regeneration

  7. Phosphorylation of beta1-AR by PKA stimulates active Ca(2 (show CA2 Proteins)+)influx through TRPV5 (show TRPV5 Proteins).

  8. This study report that both beta1- and beta2-ARs (show SLURP1 Proteins) are expressed in a majority of GABAergic interneurons in the medial prefrontal cortex of mice.

  9. Calcium {Ca(2 (show CA2 Proteins)+)} entry through beta-adrenergic-stimulated LTCC underlies hypoxia-induced [Ca(2 (show CA2 Proteins)+)]i overload and the ensuing loss of mitochondrial function in intact heart.

  10. Data indicate that ischemic injury coupled to G protein-coupled receptor beta1/2 adrenergic receptors activation required GRK2 (GPCR kinase 2) activation.

Cow (Bovine) Adrenergic, beta-1-, Receptor (ADRB1) interaction partners

Human Adrenergic, beta-1-, Receptor (ADRB1) interaction partners

  1. Suggest a common regulatory pattern for the beta(1)-AR/GRK5 (show GRK5 Proteins) which is independent of cellular type or pathology.

  2. In healthy individuals, heart rate and renin (show REN Proteins) responses to dobutamine were more than three-fold greater among ADRB1 Arg389 compared with Gly389 homozygotes.

  3. ADRB1 is associated with heart rate recovery after exercise.

  4. Ser49Gly polymorphism of the ADRB1 gene confer higher risk of ischemic stroke in a North Indian population.

  5. There was no significant interaction between the effects of ADRB1 and CYP2D6 (show CYP2D6 Proteins) gene polymorphisms on treatment outcome. Patients homozygous for the mutant ADRB1 genotype (CC) had better treatment outcomes than those heterozygous for the mutation (GC).

  6. This study sought to identify the distributed characteristics of these variant genotypes in Chinese population, and influence of GRK5 (show GRK5 Proteins) and ADRB1 polymorphisms on systolic heart failure morbidity.

  7. This evidence, in combination with clinical studies, may contribute to a detailed analysis of the pattern of susceptibility to CVD involved in b-ADR1 receptor mechanism failure.

  8. The variant Arg389Gly of ADRB1 was statistically associated with an increase of LDL

  9. Our data suggest that PIST (show GOPC Proteins) contributes to the fine-tuning of b1AR sorting both during biosynthetic and postendocytic trafficking

  10. Arg389 polymorphism of the ADRB1 gene and Gln27 polymorphism of the ADRB2 (show ADRB2 Proteins) gene were associated with the hypotensive response to topic betaxolol in healthy Mexican volunteers.

Pig (Porcine) Adrenergic, beta-1-, Receptor (ADRB1) interaction partners

Adrenergic, beta-1-, Receptor (ADRB1) Protein Profile

Protein Summary

The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure.

Gene names and symbols associated with ADRB1

  • adrenergic, beta, receptor kinase 1 (ADRBK1)
  • beta-4C adrenergic receptor-like (LOC430991)
  • adrenoceptor beta 1 (ADRB1)
  • adrenergic receptor, beta 1 (adrb1)
  • adrenergic, beta, receptor kinase 1 (LOC100227701)
  • adrenergic receptor, beta 1 (Adrb1)
  • adrenergic, beta-1-, receptor (ADRB1)
  • adrenoceptor beta 1 (Adrb1)
  • adrenoceptor beta 1 (adrb1)
  • Adrb-1 protein
  • ADRB1 protein
  • ADRB1R protein
  • ADRB3 protein
  • ADRBK1 protein
  • B1AR protein
  • BAR1 protein
  • beta-AR protein
  • BETA1AR protein
  • RATB1AR protein
  • RHR protein
  • X-Beta1AR protein
  • zgc:194728 protein
  • zgc:194731 protein

Protein level used designations for ADRB1

beta-adrenergic receptor kinase 1 , adrenergic, beta-1-, receptor , adrenoceptor beta 1 , adrenoceptor beta 3 , beta adrenergic receptor kinase 1 , beta-1-adrenergic receptor , beta-1 adrenergic receptor , tripartite motif-containing 75 , adrenergic, beta, receptor kinase 1 , beta-adrenergic receptor kinase 1-like , beta1-adrenergic G-protein-coupled receptor , beta 1-AR , beta-1 adrenoceptor , beta-1 adrenoreceptor , cardiac beta adrenergic receptor , beta 1 adrenergic receptor , adrenergic receptor, beta 1 , beta 1-adrenergic receptor beta 1-AR , beta 1 adrenergic protein , Beta-1 adrenergic receptor , G-protein-coupled hormone receptor , beta 1-adrenergic receptor

GENE ID SPECIES
426000 Gallus gallus
430991 Gallus gallus
451363 Pan troglodytes
466206 Pan troglodytes
557194 Danio rerio
721754 Macaca mulatta
100227701 Taeniopygia guttata
100379595 Cavia porcellus
100461893 Pongo abelii
483701 Canis lupus familiaris
100189602 Meleagris gallopavo
11554 Mus musculus
281604 Bos taurus
153 Homo sapiens
24925 Rattus norvegicus
493972 Canis lupus familiaris
397355 Sus scrofa
493971 Felis catus
443528 Ovis aries
399337 Xenopus laevis
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