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Adrenomedullin Proteins (ADM)

Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. Additionally we are shipping Adrenomedullin Antibodies (237) and Adrenomedullin Kits (101) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ADM 25026 P43145
ADM 133 P35318
ADM 11535 P97297
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Top Adrenomedullin Proteins at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human Fc Tag 50 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$862.40
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 11 to 13 Days
$950.40
Details
HOST_Escherichia coli (E. coli) Cow His tag 100 μg Log in to see 11 to 13 Days
$985.60
Details
HOST_Escherichia coli (E. coli) Dog His tag 100 μg Log in to see 11 to 13 Days
$1,031.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$968.00
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,030.69
Details
HOST_Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,125.10
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,140.84
Details

ADM Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human , , ,
, ,
Mouse (Murine)

Top referenced Adrenomedullin Proteins

  1. Human Adrenomedullin Protein expressed in Human Cells - ABIN2004468 : Hao, Yu, Qi, Luo, Wang: The antifibrosis effect of adrenomedullin in human lung fibroblasts. in Experimental lung research 2011 (PubMed)

More Proteins for Adrenomedullin (ADM) Interaction Partners

Human Adrenomedullin (ADM) interaction partners

  1. conclusion supplementation with selenium and coenzyme Q10 (show EIF2C2 Proteins) during four years resulted in less concentration of both copeptin (show AVP Proteins) and MR-proADM

  2. High Adrenomedullin expression is associated with Malignant Pleural Mesothelioma.

  3. Among adrenomedullin, CRP (show CRP Proteins), and PCT (show UROD Proteins), procalcitonin demonstrates the highest correlation with the severity of infection.

  4. Results suggest that ADM plays an important role in intrahepatic cholangiocellular carcinoma metastasis, and that ADM signaling of epithelial-mesenchymal transition may represent a valuable therapeutic target in cancer patients.

  5. targeting of the ADM/ADM acceptors/ERK1/2/Bcl-2 (show BCL2 Proteins) pathway may provide a potential strategy through which to induce the apoptosis of osteosarcoma cells.

  6. In addition to its role in the complement system, complement factor H (show CFH Proteins) has an another role, as a binding protein for the regulatory peptide adrenomedullin. (Review)

  7. AM expression gets rapidly activated by hypoxia through a HIF-1alpha (show HIF1A Proteins) mediated mechanism, thus characterizing AM as a major survival factor for tumour cells

  8. Allelic variation in ADM and increased plasma MR-proADM are associated with susceptibility to progression of diabetic kidney disease in type 2 diabetic patients.

  9. Adrenomedullin potentiates osteolytic responses in bone to metastatic breast cancer cells.

  10. Plasma adrenomedullin level is enhanced in nasopharyngeal carcinoma.Adrenomedullin is correlated with stage progression and with long-term survival of nasopharyngeal carcinoma patients.

Mouse (Murine) Adrenomedullin (ADM) interaction partners

  1. vascular dysfunction was potentially augmented by a decrease in production of the pulmonary vasodilator adrenomedullin

  2. It was concluded that ADM may regulate chloride and fluid secretion from the seminal vesicle, which may affect the composition of the seminal plasma bathing the sperm and, hence, fertility.

  3. Estrogen-induced microRNAs are important for balancing cardiac Adm expression in female mice.

  4. These results indicate the AM-RAMP2 (show RAMP2 Proteins) system works to protect nerve cells from both acute and chronic cerebral ischemia by maintaining cerebral blood flow suppressing oxidative stress, and in the case of chronic ischemia, enhancing capillary growth.

  5. Epicardial-derived adrenomedullin drives cardiac hyperplasia during embryogenesis.

  6. The endogenous adrenomedullin gene exhibits an antioxidant action via the inhibition of NADPH oxidase (show NOX1 Proteins) probably by suppressing the local renin (show REN Proteins)-angiotensin system.

  7. Hypoxia upregulates expression of the Notch ligand Dll4 (show DLL4 Proteins) and increases Notch (show NOTCH1 Proteins) signaling in a process requiring the vasoactive hormone adrenomedullin.

  8. Adrenomedullin-RAMP2 (show RAMP2 Proteins) system is crucially involved in retinal angiogenesis.

  9. ADM signaling is involved in laser-induced CNV formation, because both an ADM antagonist and ADM mAb significantly inhibited it.

  10. Endogenous adrenomedullin is a key factor in secondary lymphedema pathogenesis and provides experimental in vivo evidence of an underlying germ-line genetic predisposition to developing this disorder.

Cow (Bovine) Adrenomedullin (ADM) interaction partners

  1. Data indicate that adrenomedullin mRNA and protein signal were only found in trophoblast binucleate cells (BNCs), whereas those of CRLR (show CALCRL Proteins), RAMP2 (show RAMP2 Proteins) and RAMP3 (show RAMP3 Proteins) were detected in cotyledonary villous and caruncular epithelial cells.

  2. The present study thus showed that neither leptin (show LEP Proteins) nor resistin (show RETN Proteins) affects the expression of endothelin-1 (show EDN1 Proteins) or adrenomedullin in bovine brain microvascular endothelial cells.

Pig (Porcine) Adrenomedullin (ADM) interaction partners

  1. Data suggest that ADM (adrenomedullin) increases oviductal fluid secretion via chloride secretion by calcium and cAMP signal pathways (not nitric oxide signal pathway) via CGRPR (show CALCRL Proteins) (calcitonin gene-related peptide (show CALCA Proteins) receptor; not adrenomedullin receptor (show GPR182 Proteins)).

  2. adrenomedullin prevented loss of cerebral autoregulation after fluid percussion injury in a sex-dependent and ERK MAPK (show MAPK1 Proteins)-dependent manner

Adrenomedullin (ADM) Protein Profile

Protein Summary

Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element.

Gene names and symbols associated with Adrenomedullin Proteins (ADM)

  • adrenomedullin (ADM)
  • adrenomedullin (adm)
  • adrenomedullin (Adm)
  • adrenomedullin (LOC100347461)
  • adrenomedullin (AMPP)
  • ADM protein
  • AM protein
  • Ap protein
  • H39316 protein
  • RATAP protein

Protein level used designations for Adrenomedullin Proteins (ADM)

adrenomedullin , ADM , preproadrenomedullin , pro-adrenomedullin

GENE ID SPECIES
451021 Pan troglodytes
703305 Macaca mulatta
100135021 Xenopus (Silurana) tropicalis
25026 Rattus norvegicus
133 Homo sapiens
403817 Canis lupus familiaris
423042 Gallus gallus
11535 Mus musculus
100347461 Oryctolagus cuniculus
280713 Bos taurus
397195 Sus scrofa
100733203 Cavia porcellus
101103753 Ovis aries
100033857 Equus caballus
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