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Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Additionally we are shipping ACER3 Antibodies (30) and and many more products for this protein.
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ACER3 catalyzes the hydrolysis of unsaturated long chain ceramides and dihydroceramides and coordinates with ACER2 (show ACER2 ELISA Kits) to regulate cell proliferation and survival
Alkaline ceramidase 3 expression has an important role in the innate immune response by regulating the expression of pro-inflammatory cytokines in cells of the innate immune system through C18:1-ceramide.
Acer3 plays critically protective roles in controlling the homeostasis of various sphingolipids, including ceramides, sphingosine, S1P (show S1PR1 ELISA Kits), and certain complex sphingolipids in the brain and protects Purkinje cells from premature degeneration.
Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity).
, alkCDase 3
, alkaline CDase 3
, alkaline dihydroceramidase SB89
, alkaline phytoceramidase