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The protein encoded by APPBP2 interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. Additionally we are shipping Amyloid beta Precursor Protein (Cytoplasmic Tail) Binding Protein 2 Kits (10) and Amyloid beta Precursor Protein (Cytoplasmic Tail) Binding Protein 2 Proteins (5) and many more products for this protein.
Showing 10 out of 103 products:
Human Polyclonal APPBP2 Primary Antibody for EIA, WB - ABIN950471
Benboudjema, Mulvey, Gao, Pimplikar, Mohr: Association of the herpes simplex virus type 1 Us11 gene product with the cellular kinesin light-chain-related protein PAT1 results in the redistribution of both polypeptides. in Journal of virology 2003
Show all 5 references for ABIN950471
Human Polyclonal APPBP2 Primary Antibody for EIA, WB - ABIN359514
Zheng, Eastman, Vande Pol, Pimplikar: PAT1, a microtubule-interacting protein, recognizes the basolateral sorting signal of amyloid precursor protein. in Proceedings of the National Academy of Sciences of the United States of America 1999
It facilitates the regulator of calcineurin 1 (show RCAN1 Antibodies)-mediated apoptosis by downregulating proteasome subunits.
Sertraline is an apparent non-competitive inhibitor of PAT1-mediated transport.
Data suggest that PAT1 in enterocytes is responsible for intestinal absorption of some of the alkaloids from areca nut (i.e., arecaidine, guvacine, isoguvacine).
estrogen attenuates the activity of PAT1 by directly closing PAT1
In hPAT1 expressing oocytes Gly-Tyr (show TYR Antibodies), Gly-Pro, and Gly-Phe inhibited currents induced by drug substances.
In human cells, SLC36A1 (show SLC36A1 Antibodies) localized on intracellular membranes is required for amino acid-dependent mTORC1 activation and cell proliferation. SLC36A1 (show SLC36A1 Antibodies) also has similar in vivo growth regulatory activity to fly SLC36 AAAPs when expressed in Drosophila.
Association of the herpes simplex virus type 1 Us11 gene product with the cellular kinesin light-chain-related protein PAT1 results in the redistribution of both polypeptides.
PAT1 expressed exclusively in apical membrane of Caco-2 cells. hPAT1 may be responsible for H(+)-coupled amino acid transport expressed in apical membrane of Caco-2 cells.
Amino acid uptake via hPAT1 is inhibited by activators of the cAMP pathway indirectly through inhibition of NHE3 (show SLC9A3 Antibodies) activity.
PAT1a (show PATL2 Antibodies), which is 99.0% identical to protein interacting with APP tail 1 (PAT1), is a functional link between the transport and processing of beta-amyloid precursor protein APP and its two paralogs APLP1 (show APLP1 Antibodies) and APLP2 (show APLP2 Antibodies) in vivo.
This gene encodes a member of the eukaryote-specific amino acid/auxin permease (AAAP) 1 transporter family. The encoded protein functions as a proton-dependent, small amino acid transporter. This gene is clustered with related family members on chromosome 5q33.1.
amyloid protein-binding protein 2
, amyloid beta precursor protein (cytoplasmic tail) binding protein 2
, amyloid beta precursor protein-binding protein 2
, amyloid beta precursor protein-binding protein 2-like
, amyloid protein-binding protein 2-like
, protein interacting with APP tail 1
, lysosomal amino acid transporter 1
, proton-coupled amino acid transporter 1
, proton/amino acid transporter 1
, solute carrier family 36 member 1