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Candidate tumor suppressor gene (By similarity). Additionally we are shipping AIG1 Antibodies (42) and AIG1 Kits (9) and many more products for this protein.
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These results indicate that AIG1 and ADTRP are founding members of an evolutionarily conserved class of transmembrane threonine hydrolases involved in bioactive lipid metabolism.
identified a novel Pirh2 (show RCHY1 Proteins)-interacting protein, AIG1, by yeast two-hybrid screening and confirmed its interaction with p53 (show TP53 Proteins) both in vitro and in vivo
Immunoblotting of mouse tissues demonstrated highest expression of AIG1 in the liver, lung and heart. AIG1 has a complex genomic organization and expresses several splice variants in a tissue-dependent manner; AIG1 over-expression slightly increased susceptibility to oxidative stress. These results indicate that AIG1 plays a role in the control of the intracellular Ca(2 (show CA2 Proteins)+) concentration and cell death susceptibility.
Candidate tumor suppressor gene (By similarity). May contribute to specialized endoplasmic reticulum functions in neurons (By similarity).
androgen-induced gene 1 protein
, acupuncture induced gene 1
, acupuncture-induced protein 1-L
, brain-specific receptor-like protein B
, seizure 6-like protein