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Acts as a calcium-activated chloride channel. Additionally we are shipping ANO1 Proteins (8) and ANO1 Kits (1) and many more products for this protein.
Showing 10 out of 319 products:
Human Monoclonal ANO1 Primary Antibody for IHC (p) - ABIN1689062
Michelucci, Chiappetta, Cacciotti, Veccia, Astri, Leopizzi, Prosperi Porta, Petrozza, Della Rocca, Bevilacqua, Cavazzana, Di Cristofano: The KIT Exon 11 Stop Codon Mutation in Gastrointestinal Stromal Tumors: What Is the Clinical Meaning? in Gut and liver 2013
Show all 26 references for ABIN1689062
Human Polyclonal ANO1 Primary Antibody for EIA, IF - ABIN500970
Rock, Futtner, Harfe: The transmembrane protein TMEM16A is required for normal development of the murine trachea. in Developmental biology 2008
Show all 5 references for ABIN500970
Human Monoclonal ANO1 Primary Antibody for IHC, IHC (fro) - ABIN4305778
Namkung, Yao, Finkbeiner, Verkman: Small-molecule activators of TMEM16A, a calcium-activated chloride channel, stimulate epithelial chloride secretion and intestinal contraction. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011
Show all 2 references for ABIN4305778
Human Polyclonal ANO1 Primary Antibody for IHC, WB - ABIN4305781
Li, Wang, Chen, Jiang, Tu, Li, Yin: TMEM16A contributes to angiotensin II-induced cerebral vasoconstriction via the RhoA/ROCK signaling pathway. in Molecular medicine reports 2016
Human Polyclonal ANO1 Primary Antibody for EIA, WB - ABIN493518
Caputo, Caci, Ferrera, Pedemonte, Barsanti, Sondo, Pfeffer, Ravazzolo, Zegarra-Moran, Galietta: TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity. in Science (New York, N.Y.) 2008
Chicken Polyclonal ANO1 Primary Antibody for WB - ABIN2775453
Katoh, Katoh: Identification and characterization of TMEM16E and TMEM16F genes in silico. in International journal of oncology 2004
Results showed that DOG1 expression was consistently positive in breast myoepithelial cells (MEC (show CCL28 Antibodies)), and is then a useful MEC (show CCL28 Antibodies) marker providing more sophisticated information when diagnosing uncertain cases in the breast.
ANO1 on ICCs makes a key contribution to generation and regulation of pacemaker electrical slow-wave activity.
Data show that calcium-activated chloride channel TMEM16 overexpression correlates with decreased survival in human papilloma virus -negative tumors.
DOG1 was expressed in 66% of CD117(+) GISTs and highly associated with tumor size and the rate of wild-type tumors
DOG1 positivity in select non-GIST tumors.
Our results indicated that both the electrical property and the size of the side-chain at residue 447 have significant effects on Ca(2 (show CA2 Antibodies)+) dependent gating of TMEM16A.
ANO1 expression and gene amplification showed no significant associations with clinicopathological parameters in HNSCC.
DOG1 is a sensitive marker in the diagnosis of acinic cell carcinoma
TCGA analysis showed that ANO1 and FADD, located at 11q13, were co-expressed at transcript level and significantly associated with overall and disease-free survival
Aberrant c-KIT (show KIT Antibodies) and DOG-1 expressions in CRC (show CALR Antibodies) are rare events, either in NMA (show BAMBI Antibodies) or MA.
Data indicate that anoctamin channel proteins ANO1 and ANO2 (show ANO2 Antibodies) are expressed in the cerebellum.
Ano1 may play a role in the pathophysiological processes during ischaemia in heart, and therefore, Ano1 might be a potential therapeutic target to prevent ischaemic damage
Thegenetic ablation of TMEM16A did not seem to affect the maturation of olfactory sensory neurons and their ciliary layer.
Suggest Ca(2 (show CA2 Antibodies)+)-dependent push-pull conformational change as a key electromechanical movement for gating the ANO1 channel.
These results indicate ANO1 channels are involved with TRPV1 (show TRPV1 Antibodies) actions in sensory neurons and inhibition of ANO1 could be a novel means of inducing analgesia.
Basolateral Ano1 supports CCH-induced Ca2 (show CA2 Antibodies)+ signaling and secretion via luminal CFTR (show CFTR Antibodies).
By inhibiting TRPM7 (show TRPM7 Antibodies) and ANO1 via opioid receptor signaling pathways.
TMEM16A is an essential component of Ca(2 (show CA2 Antibodies)+)-activated Cl(-) currents in mouse vomeronasal sensory neurons.
conclude that ANO1 encodes Ca(2 (show CA2 Antibodies)+)-activated chloride (Cl(-)) channel and plays a significant role in the phase 1 repolarization of action potentials
TMEM16A and myocardin (show MYOCD Antibodies) form a positive feedback loop that is disrupted by KLF5 (show KLF5 Antibodies) during Ang II (show AGT Antibodies)-induced vascular remodeling.
Acts as a calcium-activated chloride channel. Required for normal tracheal development (By similarity).
anoctamin 1, calcium activated chloride channel
, Ca-activated chloride channel Tmem16A
, discovered on gastrointestinal stromal tumors protein 1
, oral cancer overexpressed 2
, transmembrane protein 16A (eight membrane-spanning domains)
, tumor-amplified and overexpressed sequence 2
, transmembrane protein 16A