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ANO1 antibody

ANO1 Reactivity: Human, Mouse, Rat IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7255333
  • Target See all ANO1 Antibodies
    ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))
    Reactivity
    • 127
    • 30
    • 28
    • 7
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 81
    • 50
    Rabbit
    Clonality
    • 67
    • 64
    Polyclonal
    Conjugate
    • 57
    • 13
    • 9
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ANO1 antibody is un-conjugated
    Application
    • 63
    • 51
    • 43
    • 37
    • 35
    • 20
    • 18
    • 13
    • 13
    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human ANO1 (NP_060513.5).
    Isotype
    IgG
    Top Product
    Discover our top product ANO1 Primary Antibody
  • Application Notes
    IF 1:100-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))
    Alternative Name
    ANO1 (ANO1 Products)
    Synonyms
    DOG1 antibody, ORAOV2 antibody, TAOS2 antibody, TMEM16A antibody, Tmem16a antibody, anoctamin 1 antibody, anoctamin 1, calcium activated chloride channel antibody, Ano1 antibody, ANO1 antibody
    Background
    TMEM16A, also known as DOG1, ORAOV2, TAOS2 or ANO1 (anoctamin 1), is a 986 amino acid multi-pass membrane protein that localizes to both the cell membrane and the cytoplasm and belongs to the anoctamin family. Expressed in a variety of tissues with highest expression in skeletal muscle and liver, TMEM16A functions as a calcium-activated chloride channel that is required for normal tracheal development. Human TMEM16A shares 90 % sequence identity with its mouse counterpart, suggesting a conserved role between species. TMEM16A is present in breast, pancreatic, gastric, and uterine cancers, as well as in neck, ovarian and parathyroid tumors, suggesting a role for TMEM16A in carcinogenesis. Three isoforms of TMEM16A exist due to alternative splicing events.
    Gene ID
    55107
    UniProt
    Q5XXA6
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