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Anterior Gradient Homolog 2 (Xenopus Laevis) Proteins (AGR2)

Required for MUC2 post-transcriptional synthesis and secretion. Additionally we are shipping AGR2 Antibodies (253) and AGR2 Kits (27) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
AGR2 10551 O95994
AGR2 23795 O88312
AGR2 298961  
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Top AGR2 Proteins at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag 50 μg Log in to see 2 to 3 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$616.00
Details
HOST_Escherichia coli (E. coli) Rat His tag,S tag   100 μg Log in to see 11 to 13 Days
$616.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag,S tag   100 μg Log in to see 11 to 13 Days
$633.60
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,311.83
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,311.83
Details

AGR2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
,
Mouse (Murine)
,
Rat (Rattus)

Top referenced AGR2 Proteins

  1. Human AGR2 Protein expressed in HEK-293 Cells - ABIN2180575 : Fletcher, Patel, Tyson, Adam, Schenker, Loader, Daviet, Legrain, Parekh, Harris, Terrett: hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan. in British journal of cancer 2003 (PubMed)
    Show all 4 references for ABIN2180575

  2. Human AGR2 Protein expressed in Escherichia coli (E. coli) - ABIN667050 : Fritzsche, Dahl, Dankof, Burkhardt, Pahl, Petersen, Dietel, Kristiansen: Expression of AGR2 in non small cell lung cancer. in Histology and histopathology 2007 (PubMed)
    Show all 3 references for ABIN667050

  3. Human AGR2 Protein expressed in Wheat germ - ABIN1344592 : Di Maro, Salerno, Unger, Orlandella, Monaco, Chiappetta, Thomas, Oczko-Wojciechowska, Masullo, Jarzab, Santoro, Salvatore: Anterior gradient protein 2 promotes survival, migration and invasion of papillary thyroid carcinoma cells. in Molecular cancer 2014 (PubMed)

More Proteins for Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2) Interaction Partners

Zebrafish Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2) interaction partners

  1. Agr2 is essential for terminal differentiation of intestinal goblet cells in zebrafish embryos

  2. Both phylogenetic and syntenic analyses indicate that zebrafish agr2 is the orthologue of human AGR2 and mouse Agr2 genes.

Human Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2) interaction partners

  1. Results show that AGR2 is O-glycosylated upon secretion from human and rat cell lines, and that this form of the protein is released from healthy cells and not as a result of cell lysis.

  2. Nearly all NSCLC tumors show AGR2 expression. Lung cancer expression of AGR2 has prognostic value for younger patients.

  3. These data together identify the single cysteine of AGR2 as an oxidant responsive moiety that regulates its propensity for oxidation and its monomeric-dimeric state.

  4. The prognostic impact of AGR2 expression could be related to treatment outcome in estrogen receptor (show ESR1 Proteins)-positive breast cancers and/or its metastasis-promoting effects.

  5. analysis of molecular characteristics, function, and regulation of AGR2 in cancer[review]

  6. AGR2 was higher in HNSCC than in normal oral mucosa. High levels were associated with the T category, pathological grade and lymphatic metastasis. AGR2 expression increased in recurring HNSCC after radiotherapy or cisplatin-based chemotherapy.

  7. The mechanism linking the IGF-1 (show IGF1 Proteins)/insulin (show INS Proteins) signal and AGR2 promoter activation is important.

  8. Data show the potential usability of anterior gradient homolog 3 (AGR3 (show AGR3 Proteins)) and anterior gradient homolog 2 (AGR2) as biomarkers for blood-based early detection of breast cancer.

  9. Our findings, for the first time, describe AGR2 as an important regulator in chemical hypoxia-induced doxorubicin resistance in breast cancer cells

  10. Relying on available data and in silico analyses, study shows that AGR2 and AGR3 (show AGR3 Proteins) proteins are co-expressed or uncoupled in context-dependent manners in diverse carcinomas and healthy tissues.

Mouse (Murine) Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2) interaction partners

  1. EGFR (show EGFR Proteins)-mediated signaling in NCI-H460 cells is disrupted with reduced AGR2 expression.

  2. AGR2 has both intracellular and extracellular effects in the intestine

  3. Results indicate that DNA methylation (show HELLS Proteins) within the AGR2 promoter modulates more aggressive cancer cell phenotypes.

  4. It was concluded that: the expression of AGR2 protein was significantly higher in asthmatic mice as compared with their normal counterparts; the expression was obviously related to the expression of Muc5ac protein and IL-13 (show IL13 Proteins).

  5. Agr2 consequently serves to maintain the balance between proliferating and differentiated epithelial cells.

  6. Agr2 facilitates normal lobuloalveolar development by regulating mammary epithelial cell proliferation; we found no effects on apoptosis in Agr2(-/-) mammary epithelial cells.

  7. Loss of Foxp1 (show FOXP1 Proteins)/4 in the developing lung and in postnatal secretory epithelium leads to ectopic activation of the goblet cell fate program, in part, through de-repression of the protein disulfide isomerase (show P4HB Proteins) anterior gradient 2 (Agr2).

  8. studies implicate Agr2 in intestinal homeostasis and ER stress and suggest a role in the etiology of inflammatory bowel disease

  9. AGR2 may be important for the growth and development of the intestine as well as esophageal adenocarcinomas.

  10. Overexpression of Agr2 is associated with asthma.

AGR2 Protein Profile

Protein Summary

Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells. Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth (By similarity).

Gene names and symbols associated with AGR2

  • anterior gradient 3 (agr3)
  • anterior gradient 2 homolog (LOC100329406)
  • anterior gradient 2 (AGR2)
  • anterior gradient 2 (Agr2)
  • anterior gradient 2 homolog (Xenopus laevis) (Agr2)
  • anterior gradient 2 homolog (Xenopus laevis) (AGR2)
  • anterior gradient homolog 2 (Xenopus laevis) (AGR2)
  • anterior gradient homolog 2 (Xenopus laevis) (agr2)
  • AG2 protein
  • agr2 protein
  • Agr2h protein
  • bcmp11 protein
  • Gob-4 protein
  • HAG-2 protein
  • hag-3 protein
  • hag3 protein
  • mAG-2 protein
  • MGC89004 protein
  • PDIA17 protein
  • wu:fj29g05 protein
  • XAG-2 protein
  • zgc:112187 protein

Protein level used designations for AGR2

anterior gradient 3 , anterior gradient 2 homolog , AG-2 , HPC8 , anterior gradient homolog 2 , anterior gradient protein 2 homolog , protein disulfide isomerase family A, member 17 , secreted cement gland homolog , secreted cement gland protein XAG-2 homolog , protein Gob-4 , anterior gradient 2 homologue

GENE ID SPECIES
448756 Xenopus (Silurana) tropicalis
100329406 Danio rerio
10551 Homo sapiens
23795 Mus musculus
298961 Rattus norvegicus
482333 Canis lupus familiaris
100174601 Pongo abelii
100514482 Sus scrofa
415112 Bos taurus
335616 Danio rerio
420596 Gallus gallus
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