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Apelin Receptor Proteins (APLNR)

APLNR encodes a member of the G protein-coupled receptor gene family. Additionally we are shipping Apelin Receptor Antibodies (130) and Apelin Receptor Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
APLNR 23796 Q9WV08
Rat APLNR APLNR 83518 Q9JHG3
APLNR 187 P35414
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Top Apelin Receptor Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 9 Days
$491.43
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

APLNR Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for Apelin Receptor (APLNR) Interaction Partners

Cow (Bovine) Apelin Receptor (APLNR) interaction partners

  1. APJ receptor in granulosa cells and both apelin (show APLN Proteins) and the APJ receptor in theca tissues are expressed in bovine ovary.

  2. The data suggest that apelin (show APLN Proteins)/APJ system is involved in the mechanism regulating angiogenesis during follicle maturation as well as during corpora lutea formation and function in the bovine ovary.

Mouse (Murine) Apelin Receptor (APLNR) interaction partners

  1. Endothelial CXCR4 (show CXCR4 Proteins) is negatively regulated by miR (show MLXIP Proteins)-139-5p, whose transcription is in turn induced by laminar flow and APLN (show APLN Proteins)/APLNR signalling.

  2. apelin (show APLN Proteins) is produced by arterial endothelial cells (ECs) during embryogenesis, induces chemotaxis of venous ECs, and promotes the production of secreted Frizzled-related protein 1 (show SFRP1 Proteins) by apelin receptor(+) ECs

  3. Findings demonstrate a stimulatory role for the islet cell apelin (show APLN Proteins)-APJ signaling axis in regulation of pancreatic islet homeostasis and in metabolic induced beta-cell hyperplasia.

  4. ERG (show ERG Proteins) and APLNR are essential for endothelial homeostasis in venules in the lung and that perturbation in ERG (show ERG Proteins)-APLNR signaling is crucial for the development of pulmonary veno-occlusive disease.

  5. These findings suggest that apelin (show APLN Proteins)-APJ signaling is a potential therapeutic target in the treatment of vasculogenic erectile dysfunction.

  6. regulates the Nodal/Bone Morphogenetic Protein antagonist Cerberus (show CER1 Proteins) and the Baf60c/Smarcd3 (show SMARCD3 Proteins) subunit of the Brg1 (show SMARCA4 Proteins)/Brm (show SMARCA2 Proteins)-associated factors (BAF (show BANF1 Proteins)) chromatin-remodelling complex

  7. In obese and insulin (show INS Proteins)-resistant mice, plasma apelin (show APLN Proteins) concentration after fasting was not modified but, the gene-expression level of the APL (show FASL Proteins)/APJ system was augmented in the white adipose tissue and reduced in the brown adipose tissue, liver and in kidneys.

  8. These findings imply that the pancreatic apelin (show APLN Proteins)-APJ system functions to curb the inflammatory and fibrosis responses during pancreatitis, and that apelin (show APLN Proteins) reduces inflammation and fibrosis by reducing neutrophil recruitment and PSC activity.

  9. More than half of the expected Apj-/- embryos died in utero because of cardiovascular developmental defects. Apelin (show APLN Proteins)-APJ signaling plays a novel role as a potent regulator of endothelial MEF2 (show MEF2C Proteins) function in the developing cardiovascular system.

  10. Apelin (show APLN Proteins)-APJ signalling may promote Fas (show FAS Proteins)-induced liver injury at least partially via JNK (show MAPK8 Proteins) activation.

Human Apelin Receptor (APLNR) interaction partners

  1. The expressions of apelin (show APLN Proteins) and APJ are significantly augmented by hypoxia through the hypoxia-inducible factor-1 alpha (HIF-1alpha (show HIF1A Proteins)) signaling pathway.

  2. obese (especially diabese) youngsters demonstrated lower serum apelin (show APLN Proteins) levels; the G212A polymorphism of the APLNR gene was found to exert a favourable effect on circulating apelin (show APLN Proteins) levels in childhood obesity

  3. Apelin (show APLN Proteins)-APJ system is a novel neurohormonal pathway, with studies to date suggesting that it may be of pathophysiologic relevance in Heart failure.

  4. apelin (show APLN Proteins) is produced by arterial endothelial cells (ECs) during embryogenesis, induces chemotaxis of venous ECs, and promotes the production of secreted Frizzled-related protein 1 (show SFRP1 Proteins) by apelin receptor(+) ECs

  5. There was a significant correlation between APJ expression in myocardium resected after 10 min with both oxygen extraction ratio and mixed venous oxygen saturation in children undergoing surgical repair.

  6. built 3 homology 3-D models of the ApelinR and revealed the conservation at the bottom of the apelin (show APLN Proteins) binding site of a hydrophobic cavity in which the C-terminal Phe of pE13F was embedded

  7. ERG (show ERG Proteins) and APLNR are essential for endothelial homeostasis in venules in the lung and that perturbation in ERG (show ERG Proteins)-APLNR signaling is crucial for the development of pulmonary veno-occlusive disease.

  8. AGTRL1 genetic polymorphisms might contribute to the development of hypertension independently and/or through complex interaction.

  9. serine 348 on the apelin receptor is a novel regulatory phosphorylation site in apelin-13-induced G protein-independent biased signaling

  10. APJ and B1R (show BDKRB1 Proteins) can form heterodimers in transfected HEK293 cells and activations of APJ and B1R (show BDKRB1 Proteins) could up-regulate eNOS (show NOS3 Proteins) phosphorylation

Apelin Receptor (APLNR) Protein Profile

Protein Summary

This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.

Gene names and symbols associated with Apelin Receptor Proteins (APLNR)

  • apelin receptor (APLNR)
  • apelin receptor (aplnr)
  • apelin receptor (LOC100348126)
  • apelin receptor (Aplnr)
  • Agtrl1 protein
  • angio1 protein
  • Apj protein
  • APJR protein
  • APLNR protein
  • DKFZp469C1532 protein
  • HG11 protein
  • msr protein
  • msr/apj protein
  • X-msr protein
  • Xangio1 protein
  • Xmsr protein

Protein level used designations for Apelin Receptor Proteins (APLNR)

angiotensin II receptor-like 1 , G-protein coupled receptor APJ , angiotensin receptor-like 1 , angiotensin receptor-related protein , apelin receptor , MSR , B78 , GPCR34 , APJ (apelin) receptor , APJ receptor , G protein-coupled receptor APJ , G-protein coupled receptor HG11 , HG11 orphan receptor

GENE ID SPECIES
483497 Canis lupus familiaris
466585 Pan troglodytes
613084 Xenopus (Silurana) tropicalis
615435 Bos taurus
100171470 Pongo abelii
100348126 Oryctolagus cuniculus
23796 Mus musculus
83518 Rattus norvegicus
187 Homo sapiens
706823 Macaca mulatta
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