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APLNR encodes a member of the G protein-coupled receptor gene family. Additionally we are shipping Apelin Receptor Kits (16) and Apelin Receptor Proteins (5) and many more products for this protein.
Showing 10 out of 163 products:
Human Polyclonal Apelin Receptor Primary Antibody for FACS, IF (p) - ABIN740160
Ustunel, Acar, Gemici, Ozbey, Edizer, Soylu, Tepekoy, Izgut-Uysal: The effects of water immersion and restraint stress on the expressions of apelin, apelin receptor (APJR) and apoptosis rate in the rat heart. in Acta histochemica 2014
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Human Monoclonal Apelin Receptor Primary Antibody for FACS, IHC - ABIN4899111
Bahrami, Pagh, Ejegod, Duch, Tolstrup, Pedersen: Construction of a gammaretrovirus with a novel tropism and wild-type replication kinetics capable of using human APJ as entry receptor. in Journal of virology 2012
Show all 2 references for 4899111
Human Monoclonal Apelin Receptor Primary Antibody for FACS - ABIN4895622
Yu, Hirst, Costa, Ng, Schiesser, Gertow, Stanley, Elefanty: APELIN promotes hematopoiesis from human embryonic stem cells. in Blood 2012
Human Polyclonal Apelin Receptor Primary Antibody for IF, ELISA - ABIN1535565
ODowd, Heiber, Chan, Heng, Tsui, Kennedy, Shi, Petronis, George, Nguyen: A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11. in Gene 1994
APJ receptor in granulosa cells and both apelin (show APLN Antibodies) and the APJ receptor in theca tissues are expressed in bovine ovary.
The data suggest that apelin (show APLN Antibodies)/APJ system is involved in the mechanism regulating angiogenesis during follicle maturation as well as during corpora lutea formation and function in the bovine ovary.
These results demonstrate a new pharmacologic property of protamine-blockade of APJ-that could explain some adverse effects observed in protamine-treated patients, and that the established antiangiogenic activity of protamine would rely on APJ antagonism.
Apelin (show APLN Antibodies)-36-[L28C(30kDa (show TAF10 Antibodies)-PEG (show PAEP Antibodies))] provides a starting point for the development of diabetes therapeutics that are devoid of the blood pressure effects associated with canonical APJ activation
Results show that obese mice had significantly lower mRNA and protein expressions of apelin (show APLN Antibodies)/ APJ in skeletal muscles than the normal body weight mice.
These results demonstrate that overexpression of APJ in cardiomyocytes has adverse effects on cardiac function in male and non-pregnant mice and that lactation contributes to the development of postpartum cardiomyopathy in the heart with APJ overexpression.
Endothelial CXCR4 (show CXCR4 Antibodies) is negatively regulated by miR (show MLXIP Antibodies)-139-5p, whose transcription is in turn induced by laminar flow and APLN (show APLN Antibodies)/APLNR signalling.
apelin (show APLN Antibodies) is produced by arterial endothelial cells (ECs) during embryogenesis, induces chemotaxis of venous ECs, and promotes the production of secreted Frizzled-related protein 1 (show SFRP1 Antibodies) by apelin receptor(+) ECs
Findings demonstrate a stimulatory role for the islet cell apelin (show APLN Antibodies)-APJ signaling axis in regulation of pancreatic islet homeostasis and in metabolic induced beta-cell hyperplasia.
ERG (show ERG Antibodies) and APLNR are essential for endothelial homeostasis in venules in the lung and that perturbation in ERG (show ERG Antibodies)-APLNR signaling is crucial for the development of pulmonary veno-occlusive disease.
These findings suggest that apelin (show APLN Antibodies)-APJ signaling is a potential therapeutic target in the treatment of vasculogenic erectile dysfunction.
regulates the Nodal/Bone Morphogenetic Protein antagonist Cerberus (show CER1 Antibodies) and the Baf60c/Smarcd3 (show SMARCD3 Antibodies) subunit of the Brg1 (show SMARCA4 Antibodies)/Brm (show SMARCA2 Antibodies)-associated factors (BAF (show BANF1 Antibodies)) chromatin-remodelling complex
The apelin (show APLN Antibodies)/APLNR axis regulates cholangiocarcinoma cell proliferation and tumor angiogenesis.
Data suggest that the differential expression of Apelin (show APLN Antibodies) and Apelin receptor APJ yields a "self-generated" gradient mechanisms that accelerates the extension of the sprout.
The aim of this study was to evaluate if polymorphisms of APLN (show APLN Antibodies) and APLNR genes may play a role as susceptibility markers for hypertension in a group of Mexican-Mestizo patients.
review of the important role of the Apelin (show APLN Antibodies)/APJ system in pathological angiogenesis
The optimal gene-gene interaction model for both males and females with regard to hypertension was apelin (show APLN Antibodies) rs3761581-apelin (show APLN Antibodies) rs3115757-APJ rs7119375. In conclusion, gene polymorphisms of the apelin (show APLN Antibodies)-APJ system are associated with susceptibility to hypertension.
Up-regulation of apelin (show APLN Antibodies) and APJ expression plays an important role in cardioprotection from myocardial ischemia/reperfusion injury.
These findings suggested that Apelin (show APLN Antibodies)/APLNR signaling may be used as a potential therapeutic target for hypoxic/ischemic injury.
The expressions of apelin (show APLN Antibodies) and APJ are significantly augmented by hypoxia through the hypoxia-inducible factor-1 alpha (HIF-1alpha (show HIF1A Antibodies)) signaling pathway.
obese (especially diabese) youngsters demonstrated lower serum apelin (show APLN Antibodies) levels; the G212A polymorphism of the APLNR gene was found to exert a favourable effect on circulating apelin (show APLN Antibodies) levels in childhood obesity
This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.
angiotensin II receptor-like 1
, G-protein coupled receptor APJ
, angiotensin receptor-like 1
, angiotensin receptor-related protein
, apelin receptor
, APJ (apelin) receptor
, APJ receptor
, G protein-coupled receptor APJ
, G-protein coupled receptor HG11
, HG11 orphan receptor