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anti-ArfGAP with Coiled-Coil, Ankyrin Repeat and PH Domains 1 (ACAP1) Antibodies

GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface.. Additionally we are shipping ACAP1 Kits (9) and ACAP1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ACAP1 9744 Q15027
ACAP1 216859 Q8K2H4
ACAP1 287443  
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Top anti-ACAP1 Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB ACAP1 Antibody (N-term) (ABIN655086) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, WB ACAP1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ACAP1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. ACAP1 Antibody (N-term) western blot analysis in mouse spleen tissue lysates (35 µg/lane).This demonstrates the ACAP1 antibody detected the ACAP1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated ELISA, WB EB056122 staining (0.5µg/ml) of Jurkat lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Goat Un-conjugated IHC (p), ELISA, WB Human Tonsil (formalin-fixed, paraffin-embedded) stained with CENTB1 antibody ABIN337010 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit PE IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$507.83
Details

ACAP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-ACAP1 Antibodies

  1. Human Polyclonal ACAP1 Primary Antibody for IHC (p), WB - ABIN655086 : Cuthbert, Davis, Casanova: Substrate specificities and activities of AZAP family Arf GAPs in vivo. in American journal of physiology. Cell physiology 2008 (PubMed)
    Show all 3 references for ABIN655086

  2. Human Polyclonal ACAP1 Primary Antibody for EIA, WB - ABIN950226 : Shinozaki-Narikawa, Kodama, Shibasaki: Cooperation of phosphoinositides and BAR domain proteins in endosomal tubulation. in Traffic (Copenhagen, Denmark) 2006 (PubMed)
    Show all 3 references for ABIN950226

  3. Human Polyclonal ACAP1 Primary Antibody for ELISA, WB - ABIN185096 : Jackson, Brown, Nie, Miura, Foroni, Sun, Hsu, Donaldson, Randazzo: ACAPs are arf6 GTPase-activating proteins that function in the cell periphery. in The Journal of cell biology 2000 (PubMed)

More Antibodies against ACAP1 Interaction Partners

Human ArfGAP with Coiled-Coil, Ankyrin Repeat and PH Domains 1 (ACAP1) interaction partners

  1. The serum lever of Alzheimer's disease were decrease and the expression of ACAP1 strongly correlated with the Mini-Mental State Examination scores of the AD patients

  2. ACAP1 and ARAP2 (show ARAP2 Antibodies) each colocalize with Arf6 (show ARF6 Antibodies) but they did not colocalize with each other and have opposing effects on focal adhesions.

  3. CENTB1 was up-regulated in patients with active UC as compared to UC remission and healthy control groups suggesting that it is involved in the inflammatory process.

  4. phosphorylation of ACAP1 relieves a localized mechanism of autoinhibition in regulating cargo binding

  5. the oncogenic potential of USP6 (show USP6 Antibodies) is linked to its ability to integrate cell migration and cytokinesis by regulating Arf6 (show ARF6 Antibodies)/ACAP1.

  6. ACAP1 promotes endocytic recycling by recognizing recycling sorting signals.

  7. CENTB1 selectively down-regulates NF-kappaB (show NFKB1 Antibodies) activation via NODs pathways, creating a "feedback" loop and suggesting a novel role of CENTB1 in innate immune responses to bacteria and inflammatory responses

  8. Results suggest that two ARF6 (show ARF6 Antibodies) downstream molecules, PIP5K (show PIKFYVE Antibodies) and ACAP1, function together in endosomal tubulation and that phosphoinositide levels may regulate endosomal dynamics.

  9. Results suggest that ACAP1, a GTPase-activating protein (GAP) for ADP-ribosylation factor (show ARF1 Antibodies) (ARF) 6 (show ARF6 Antibodies), is part of a novel clathrin coat complex that is regulated by ARF6 (show ARF6 Antibodies) for endocytic recycling in two key physiological settings.

  10. ACAP1 has robust, constitutive Arf6 (show ARF6 Antibodies) GAP activity in vivo, with little activity toward Arf1 (show ARF1 Antibodies).

ACAP1 Antigen Profile

Protein Summary

GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface.

Gene names and symbols associated with ACAP1

  • ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 (ACAP1) antibody
  • ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 (Acap1) antibody
  • Centb1 antibody

Protein level used designations for ACAP1

centaurin beta1 , centaurin, beta 1 , ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 , arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1-like , arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 , centaurin-beta-1 , cnt-b1 , Arf GAP with coiled coil, ANK repeat and PH domains 1

GENE ID SPECIES
455275 Pan troglodytes
721824 Macaca mulatta
100016342 Monodelphis domestica
100072970 Equus caballus
100359236 Oryctolagus cuniculus
100481518 Ailuropoda melanoleuca
100607184 Nomascus leucogenys
100623422 Sus scrofa
508582 Bos taurus
9744 Homo sapiens
216859 Mus musculus
287443 Rattus norvegicus
Selected quality suppliers for anti-ACAP1 (ACAP1) Antibodies
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