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anti-Arginine Vasopressin Receptor 2 (AVPR2) Antibodies

AVPR2 encodes the vasopressin receptor, type 2, also known as the V2 receptor, which belongs to the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily, and couples to Gs thus stimulating adenylate cyclase. Additionally we are shipping AVPR2 Kits (3) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AVPR2 554 P30518
AVPR2 12000 O88721
AVPR2 25108 Q00788
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Top anti-AVPR2 Antibodies at antibodies-online.com

Showing 10 out of 66 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from RAW264.7 cells, using AVPR2 Ant... Immunofluorescence analysis of MCF7 cells, using AVPR2 Antibody. The p... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-AVPR2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:... WB Suggested Anti-AVPR2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: ... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemical staining of kidney (renal tubules) using anti-AVPR... 50 μg Log in to see 6 to 8 Days
$500.50
Details
Chimpanzee Rabbit Un-conjugated IHC (p) Immunohistochemical staining of Kidney (Renal tubules) using anti- AVP... 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p) Anti-AVPR2 antibody  ABIN1048335 IHC staining of human kidney, renal t... 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB Western Blot showing AVPR2 antibody used at a concentration of 1-2 ug/... 50 μg Log in to see 7 to 9 Days
$473.93
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Lane 1: mouse brain lysates Lane 2: mouse kidney lysates probed with A... 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IF, ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details

AVPR2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
,
Mouse (Murine) , , , ,

Rat (Rattus) , , , ,

Top referenced anti-AVPR2 Antibodies

  1. Human Polyclonal AVPR2 Primary Antibody for WB - ABIN2801893 : Seibold, Brabet, Rosenthal, Birnbaumer: Structure and chromosomal localization of the human antidiuretic hormone receptor gene. in American journal of human genetics 1992 (PubMed)
    Show all 5 references for ABIN2801893

  2. Human Polyclonal AVPR2 Primary Antibody for IF, ELISA - ABIN1536014 : Birnbaumer, Seibold, Gilbert, Ishido, Barberis, Antaramian, Brabet, Rosenthal: Molecular cloning of the receptor for human antidiuretic hormone. in Nature 1992 (PubMed)
    Show all 2 references for ABIN1536014

  3. Human Polyclonal AVPR2 Primary Antibody for ELISA, WB - ABIN334356 : Mutig, Paliege, Kahl, Jöns, Müller-Esterl, Bachmann: Vasopressin V2 receptor expression along rat, mouse, and human renal epithelia with focus on TAL. in American journal of physiology. Renal physiology 2007 (PubMed)

  4. Human Polyclonal AVPR2 Primary Antibody for WB - ABIN929264 : Canal, Wilkinson, Cooper, Wraith, Wynn, Bigger: Circadian rhythm and suprachiasmatic nucleus alterations in the mouse model of mucopolysaccharidosis IIIB. in Behavioural brain research 2010 (PubMed)

More Antibodies against AVPR2 Interaction Partners

Human Arginine Vasopressin Receptor 2 (AVPR2) interaction partners

  1. Rescue of the N321K-V2R function by Val(4)-desmopressin action in nephrogenic diabetes insipidus.

  2. X-linked nephrogenic diabetes insipidus and severity of illness in this family is caused by a novel deletion in the AVPR2 gene

  3. AVP (show AVP Antibodies) acting at V2R does not appear to regulate water losses from body fluids other than renal excretion during exercise.

  4. This review summarizes some of the unexpected roles of V2R signaling and suggests that vasopressin (show AVP Antibodies) signaling itself may contribute crucially to loss of polarity and enhanced proliferation in cystic kidney epithelium.

  5. 52 disease-causing mutations of AVPR2 were identified. missense mutations were most common (54%), followed by deletion mutations. 64 women who had monoallelic disease-causing AVPR2 mutations, 16 had NDI symptoms, including 4 complete NDI subjects

  6. Three vasopressin (show AVP Antibodies) receptor 2 variants: an apparent polymorphism (V266A) and two loss-of-function mutations (R181C and M311V) may be related to nephrogenic syndrome of inappropriate antidiuresis and to nephrogenic diabetes insipidus.

  7. vasopressin (show AVP Antibodies) receptor type 2 signaling is controlled by retromer and arrestin (show SAG Antibodies) in a noncanonical regulatory pathway

  8. No pathological variants affecting R137 were detected among the 5,142 AVPR2 alleles successfully genotyped. Even at the population extremes of serum sodium distribution, we estimate minor allele frequency

  9. crystal structure of beta-arrestin-1 (show ARRB1 Antibodies) (also called arrestin-2 (show ARRB1 Antibodies)) in complex with a fully phosphorylated 29-amino-acid carboxy-terminal peptide derived from the human V2 vasopressin (show AVP Antibodies) receptor (V2Rpp)

  10. Investigations into primary inherited nephrogenic diabetes insipidus (NDI) have contributed enormously to our understanding of the mechanisms of urinary concentration and identified the vasopressin (show AVP Antibodies) receptor AVPR2, as well as the water channel aquaporin-2 (show AQP2 Antibodies).

Pig (Porcine) Arginine Vasopressin Receptor 2 (AVPR2) interaction partners

  1. Type 2 vasopressin (show AVP Antibodies) receptor (V2R) is in primary cilia of renal epithelial cells. There is also a functional cAMP-signaling pathway, which targets ciliary channel function and may help control the sensory function of the primary cilium.

Mouse (Murine) Arginine Vasopressin Receptor 2 (AVPR2) interaction partners

  1. Data show that cryptochrome Cry1 (show CRY1 Antibodies) and Cry2 (show CRY2 Antibodies) expression must be circadian and appropriately phased to support rhythms, and arginine vasopressin (AVP (show AVP Antibodies)) receptor signaling is required to impose circuit-level circadian function.

  2. In polycystic kidney disease, structural or functional loss of cilia leads to abnormal trafficking of AQP2 (show AQP2 Antibodies)/V2R leading to enhanced salt and water absorption.

  3. AVPR2 expression levels in the kidneys of male TALLYHO/JngJ mice, independent of diabetes disease state, were significantly reduced compared with those of B6 mice.

  4. V(2)R mRNA was expressed in medullary TAL (show TALDO1 Antibodies) (MTAL), macula densa, connecting tubule, and cortical and medullary collecting duct, and was weakly expressed in cortical TAL (show TALDO1 Antibodies) and distal convoluted tubule in rat, mouse, and human

  5. The data support roles for multiple vasopressin V2-receptor-dependent signaling pathways in the vasopressin (show AVP Antibodies) signaling network of collecting duct cells, involving several kinases not generally accepted to regulate collecting duct function.

  6. NF-kappaB (show NFKB1 Antibodies) activation is of importance for the downregulation of AQP2 (show AQP2 Antibodies) channel and vasopressin (show AVP Antibodies) V(2) receptor expression during sepsis. NF-kappaB (show NFKB1 Antibodies) inhibition ameliorates sepsis-induced acute renal failure.

  7. RNA interference methodology can be used successfully in vivo to significantly reduce functional expression of the V2R in the mouse kidney.

  8. Pax (show PXN Antibodies) transactivation domain-interacting protein is required for the urine concentration mechanism by modulating arginine vasopressin receptor 2 and AQP2 (show AQP2 Antibodies) expression in the inner medulla.

  9. RGS2 (show RGS2 Antibodies) is involved in negative feedback regulation of V2R signaling

  10. Determine expression of VR1 (show TRPV1 Antibodies)/VR2 receptors in early heart maturation.

AVPR2 Antigen Profile

Protein Summary

This gene encodes the vasopressin receptor, type 2, also known as the V2 receptor, which belongs to the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily, and couples to Gs thus stimulating adenylate cyclase. The subfamily that includes the V2 receptor, the V1a and V1b vasopressin receptors, the oxytocin receptor, and isotocin and mesotocin receptors in non-mammals, is well conserved, though several members signal via other G proteins. All bind similar cyclic nonapeptide hormones. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts, where its primary property is to respond to the pituitary hormone arginine vasopressin (AVP) by stimulating mechanisms that concentrate the urine and maintain water homeostasis in the organism. When the function of this gene is lost, the disease Nephrogenic Diabetes Insipidus (NDI) results. The V2 receptor is also expressed outside the kidney although its tissue localization is uncertain. When these 'extrarenal receptors' are stimulated by infusion of a V2 selective agonist (dDAVP), a variety of clotting factors are released into the bloodstream. The physiologic importance of this property is not known - its absence does not appear to be detrimental in NDI patients. The gene expression has also been described in fetal lung tissue and lung cancer associated with alternative splicing.

Gene names and symbols associated with AVPR2

  • arginine vasopressin receptor 2 (AVPR2) antibody
  • vasopressin V2 receptor (AVPR2) antibody
  • arginine vasopressin receptor 2 (Avpr2) antibody
  • ADHR antibody
  • AVPR2 antibody
  • DI1 antibody
  • DIR antibody
  • DIR3 antibody
  • ND1 antibody
  • NDI antibody
  • V2R antibody
  • VPV2R antibody

Protein level used designations for AVPR2

vasopressin V2 receptor , arginine vasopressin receptor 2 , AVPR V2 , antidiuretic hormone receptor , renal-type arginine vasopressin receptor , V-2 lysine vasopressin receptor , V2R , arginine vasopressin receptor 2 (nephrogenic diabetes insipidus) , nephrogenic diabetes insipidus , Vasopressin receptor V2

GENE ID SPECIES
100528011 Ovis aries
697763 Macaca mulatta
100137253 Papio anubis
100328747 Oryctolagus cuniculus
100595937 Nomascus leucogenys
554 Homo sapiens
397462 Sus scrofa
281642 Bos taurus
12000 Mus musculus
25108 Rattus norvegicus
403804 Canis lupus familiaris
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