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The protein encoded by ARNTL is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. Additionally we are shipping ARNTL Proteins (7) and ARNTL Kits (6) and many more products for this protein.
Showing 10 out of 102 products:
Human Polyclonal ARNTL Primary Antibody for ChIP, ICC - ABIN151688
Hayashida, Kuramoto, Koyanagi, Oishi, Fujiki, Matsunaga, Ikeda, Ohdo, Shimeno, Soeda: Proxisome proliferator-activated receptor-α mediates high-fat, diet-enhanced daily oscillation of plasminogen activator inhibitor-1 activity in mice. in Chronobiology international 2010
Show all 6 references for ABIN151688
Human Monoclonal ARNTL Primary Antibody for IHC, ELISA - ABIN968967
Motzkus, Loumi, Cadenas, Vinson, Forssmann, Maronde: Activation of human period-1 by PKA or CLOCK/BMAL1 is conferred by separate signal transduction pathways. in Chronobiology international 2007
Show all 3 references for ABIN968967
Human Polyclonal ARNTL Primary Antibody for WB - ABIN783300
Lee, Donehower, Herron, Moore, Fu: Disrupting circadian homeostasis of sympathetic signaling promotes tumor development in mice. in PLoS ONE 2010
Show all 3 references for ABIN783300
Human Monoclonal ARNTL Primary Antibody for FACS, IF - ABIN2452787
Trejo-Muñoz, Navarrete, Montúfar-Chaveznava, Caldelas: Temporal modulation of the canonical clockwork in the suprachiasmatic nucleus and olfactory bulb by the mammary pheromone 2MB2 in pre-visual rabbits. in Neuroscience 2014
Cow (Bovine) Polyclonal ARNTL Primary Antibody for WB - ABIN375102
Fuller, Lu, Saper: Differential rescue of light- and food-entrainable circadian rhythms. in Science (New York, N.Y.) 2008
Cow (Bovine) Polyclonal ARNTL Primary Antibody for IHC, WB - ABIN2779410
Miyazaki, Nagase, Mesaki, Narukawa, Ohara, Ishida: Phosphorylation of clock protein PER1 regulates its circadian degradation in normal human fibroblasts. in The Biochemical journal 2004
the second half of the photolyase homology region (PHR) of CRY (show CRY2 Antibodies) is important for repression through facilitating interaction with BMAL1
The BMAL1 rs2278749 T/C was associated with Alzheimer disease (AD) risk, and T carriers in BMAL1 rs2278749 T/C showed a higher risk of AD than did non-carriers.
Our results indicate that activation of TGF-beta1 (show TGFB1 Antibodies) promotes the transcriptional induction of BMAL1.
possible circadian rhythm in full-term placental expression
Synchronized cells exhibit an autonomous ultradian mitochondrial respiratory activity which is abrogated by silencing the master clock gene BMAL1.
decreased expression of Bmal1 is correlated with tumor progression and poor prognosis in pancreatic ductal adenocarcinoma, with potential to be used as a biomarker for diagnosis and prognosis
ARNTL and PER1 (show PER1 Antibodies) were associated with PD.
define a regulatory mechanism that links chondrocyte BMAL1 to the maintenance and repair of cartilage
when overexpressed, c-MYC (show MYC Antibodies) is able to repress Per1 (show PER1 Antibodies) transactivation by BMAL1/CLOCK via targeting selective E-box sequences. Importantly, upon serum stimulation, MYC (show MYC Antibodies) was detected in BMAL1 protein complexes
Bmal1 could directly bind to the p53 (show TP53 Antibodies) gene promoter and thereby transcriptionally activate the downstream tumor suppressor pathway in a p53 (show TP53 Antibodies)-dependent manner in pancreatic tumors.
Data suggest that cryptochromes mediate periodic binding of Ck2b (show CSNK2B Antibodies) (casein kinase 2beta) to Bmal1 (aryl hydrocarbon receptor nuclear translocator-like protein) and thus inhibit Bmal1-Ser90 phosphorylation by Ck2a (show CSNK2A1 Antibodies) (casein kinase 2alpha). [SYNOPSIS]
Studies indicate the broad and complex actions of brain and muscle-ARNT (show ARNT Antibodies)-like factor (Bmal1/BMAL1) on physiology and behavior.
this paper shows abnormal collagen VI expression in Bmal1-/- mice, a model for circadian rhythm deregulation
expression of oscillatory genes was dampened in the adult-life Bmal1 knockout mice, whereas overall gene expression was largely unchanged.
Bmal1 is required for beta cell compensatory expansion, survival and metabolic adaptation to diet-induced obesity in mice
BMAL1 deficiency results in a low bone mass phenotype.
Loss of Bmal1 solely from adult skeletal muscle results in reductions in specific tension, increased oxidative fibre type and increased muscle fibrosis . iMSBmal1-/- mice develop increased bone calcification and decreased joint collagen.
The amplitude of the day-night fluctuation of Bmal1 expression was reduced in the amygdala and hippocampus of light-dark-shifted mice.
circadian rhythmicity of ghrelin (show GHRL Antibodies) signaling requires Bmal1 and is driven by a food-responsive clock in the gastric ghrelin (show GHRL Antibodies)-secreting cell that not only regulates ghrelin (show GHRL Antibodies), but also GOAT activity.
Both clock- and feeding-dependent mechanisms regulate the daily accumulation of key enzymes in polyamine biosynthesis through rhythmic binding of BMAL1:CLOCK to conserved DNA elements
RNA interference screens reveal the heterodimeric, circadian rhythm Transcription factors Clock and Bmal1 as genes required for the growth of acute myeloid leukemia (show BCL11A Antibodies) cells in vitro and in vivo.
Results indicated that pBMAL1 cDNA had a coding region of 1,878 bp and shared 94.36, 89.85 and 89.79% identity with human, mouse and rat BMAL1. pBMAL1 expression levels in different tissues were studied.
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene.
aryl hydrocarbon receptor nuclear translocator-like protein 1
, brain and muscle Arnt-like protein 1
, aryl hydrocarbon receptor nuclear translocator-like
, Brain and muscle ARNT-like 1
, brain and muscle ARNT-like 1
, aryl hydrocarbon receptor nuclear translocator-like protein 1-like
, aryl hydrocarbon receptor nuclear translocater
, ARNT-like protein 1, brain and muscle
, PAS domain-containing protein 3
, bHLH-PAS protein JAP3
, basic-helix-loop-helix-PAS orphan MOP3
, basic-helix-loop-helix-PAS protein MOP3
, class E basic helix-loop-helix protein 5
, member of PAS protein 3
, member of PAS superfamily 3
, bHLH-PAS transcription factor BMAL1
, clock protein
, brain and muscle ARNT-like protein 1