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Aryl Hydrocarbon Receptor Nuclear Translocator-Like Proteins (ARNTL)

The protein encoded by ARNTL is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. Additionally we are shipping ARNTL Antibodies (84) and ARNTL Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ARNTL 406 O00327
ARNTL 11865 Q9WTL8
ARNTL 29657 Q9EPW1
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Top ARNTL Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,809.67
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ARNTL Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL) Interaction Partners

Xenopus laevis Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL) interaction partners

  1. the second half of the photolyase homology region (PHR) of CRY (show CRY2 Proteins) is important for repression through facilitating interaction with BMAL1

Human Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL) interaction partners

  1. Our results indicate that activation of TGF-beta1 (show TGFB1 Proteins) promotes the transcriptional induction of BMAL1.

  2. possible circadian rhythm in full-term placental expression

  3. Synchronized cells exhibit an autonomous ultradian mitochondrial respiratory activity which is abrogated by silencing the master clock gene BMAL1.

  4. decreased expression of Bmal1 is correlated with tumor progression and poor prognosis in pancreatic ductal adenocarcinoma, with potential to be used as a biomarker for diagnosis and prognosis

  5. ARNTL and PER1 were associated with PD.

  6. define a regulatory mechanism that links chondrocyte BMAL1 to the maintenance and repair of cartilage

  7. when overexpressed, c-MYC (show MYC Proteins) is able to repress Per1 transactivation by BMAL1/CLOCK via targeting selective E-box sequences. Importantly, upon serum stimulation, MYC (show MYC Proteins) was detected in BMAL1 protein complexes

  8. Bmal1 could directly bind to the p53 (show TP53 Proteins) gene promoter and thereby transcriptionally activate the downstream tumor suppressor pathway in a p53 (show TP53 Proteins)-dependent manner in pancreatic tumors.

  9. Data suggest that cryptochromes mediate periodic binding of Ck2b (show CSNK2B Proteins) (casein kinase 2beta) to Bmal1 (aryl hydrocarbon receptor nuclear translocator-like protein) and thus inhibit Bmal1-Ser90 phosphorylation by Ck2a (show CSNK2A1 Proteins) (casein kinase 2alpha). [SYNOPSIS]

  10. a 4-locus CSNK1E (show CSNK1E Proteins) haplotype encompassing the rs1534891 SNP (Z-score=2.685, permuted p=0.0076) and a 3-locus haplotype in ARNTL (Z-score=3.269, permuted p=0.0011) showed a significant association with Bipolar Disorder

Mouse (Murine) Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL) interaction partners

  1. Loss of Bmal1 solely from adult skeletal muscle results in reductions in specific tension, increased oxidative fibre type and increased muscle fibrosis . iMSBmal1-/- mice develop increased bone calcification and decreased joint collagen.

  2. The amplitude of the day-night fluctuation of Bmal1 expression was reduced in the amygdala and hippocampus of light-dark-shifted mice.

  3. circadian rhythmicity of ghrelin (show GHRL Proteins) signaling requires Bmal1 and is driven by a food-responsive clock in the gastric ghrelin (show GHRL Proteins)-secreting cell that not only regulates ghrelin (show GHRL Proteins), but also GOAT activity.

  4. Both clock- and feeding-dependent mechanisms regulate the daily accumulation of key enzymes in polyamine biosynthesis through rhythmic binding of BMAL1:CLOCK to conserved DNA elements

  5. RNA interference screens reveal the heterodimeric, circadian rhythm Transcription factors Clock and Bmal1 as genes required for the growth of acute myeloid leukemia (show BCL11A Proteins) cells in vitro and in vivo.

  6. Data show that brain and muscle ARNT (show ARNT Proteins) [aryl hydrocarbon receptor nuclear translocator (show ARNT Proteins)]-like protein 1 (BMAL1) deficiency impaired calorie restriction (CR)-mediated changes in the plasma levels of insulin-like growth factor I (IGF-1 (show IGF1 Proteins)).

  7. that the presence of a depressive state around the early active phase of activity may be related to impairment of rhythmicity and expression levels of Per1, Bmal1 and Per2 (show PER2 Proteins) genes under abnormal light-dark conditions

  8. Irp2 (show IREB2 Proteins) mRNA transcription is promoted by circadian clock genes, including BMAL1, and the CLOCK heterodimer.

  9. Results indicate that the C-terminal region of ARNTL transcription factor Bmal1 has pivotal roles in the regulation of circadian rhythms.

  10. Deletion of Bmal1 in ovarian theca cells disrupts ovulation, impairs fertility, and modulates LH sensitivity via LH receptor (show LHCGR Proteins) expression pattern alteration.

Pig (Porcine) Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL) interaction partners

  1. Results indicated that pBMAL1 cDNA had a coding region of 1,878 bp and shared 94.36, 89.85 and 89.79% identity with human, mouse and rat BMAL1. pBMAL1 expression levels in different tissues were studied.

Horse (Equine) Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL) interaction partners

ARNTL Protein Profile

Protein Summary

The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with ARNTL

  • aryl hydrocarbon receptor nuclear translocator-like (ARNTL)
  • aryl hydrocarbon receptor nuclear translocator-like (arntl)
  • aryl hydrocarbon receptor nuclear translocator (Arnt)
  • aryl hydrocarbon receptor nuclear translocator-like (Arntl)
  • Arnt3 protein
  • arntl protein
  • bHLHe5 protein
  • Bmal1 protein
  • BMAL1b protein
  • bmal1b' protein
  • BMAL1c protein
  • JAP3 protein
  • MOP3 protein
  • PASD3 protein
  • TIC protein
  • xBmal1 protein

Protein level used designations for ARNTL

aryl hydrocarbon receptor nuclear translocator-like protein 1 , brain and muscle Arnt-like protein 1 , aryl hydrocarbon receptor nuclear translocator-like , Brain and muscle ARNT-like 1 , brain and muscle ARNT-like 1 , aryl hydrocarbon receptor nuclear translocator-like protein 1-like , aryl hydrocarbon receptor nuclear translocater , ARNT-like protein 1, brain and muscle , PAS domain-containing protein 3 , bHLH-PAS protein JAP3 , basic-helix-loop-helix-PAS orphan MOP3 , basic-helix-loop-helix-PAS protein MOP3 , class E basic helix-loop-helix protein 5 , member of PAS protein 3 , member of PAS superfamily 3 , tic , BMAL1b' , bHLH-PAS transcription factor BMAL1 , cBMAL1 , clock protein , brain and muscle ARNT-like protein 1

GENE ID SPECIES
443262 Ovis aries
451034 Pan troglodytes
497632 Xenopus laevis
700464 Macaca mulatta
100021673 Monodelphis domestica
100173916 Pongo abelii
100303580 Saccoglossus kowalevskii
100396695 Callithrix jacchus
100482782 Ailuropoda melanoleuca
101843258 Mesocricetus auratus
406 Homo sapiens
11865 Mus musculus
29657 Rattus norvegicus
476860 Canis lupus familiaris
100037286 Sus scrofa
530705 Bos taurus
374115 Gallus gallus
100034115 Equus caballus
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