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ALG2 encodes a member of the glycosyltransferase 1 family. Additionally we are shipping ALG2 Proteins (5) and many more products for this protein.
Showing 10 out of 55 products:
Cow (Bovine) Polyclonal ALG2 Primary Antibody for WB - ABIN2783587
Draeby, Woods, la Cour, Mollerup, Bourdon, Berchtold: The calcium binding protein ALG-2 binds and stabilizes Scotin, a p53-inducible gene product localized at the endoplasmic reticulum membrane. in Archives of biochemistry and biophysics 2007
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Lack of ALG-2 (show PDCD6 Antibodies), ALIX (show PDCD6IP Antibodies) or Vps4B (show vps4b Antibodies) each prevents shedding, and repair of the injured cell membrane
Results show the crystal structure of the complex between ALG-2 (show PDCD6 Antibodies) and a peptide of Sec31A (show SEC31A Antibodies) and found that the peptide binds to the third hydrophobic pocket (Pocket 3) and that ALG-2 (show PDCD6 Antibodies) recognizing 2 types of motifs at different hydrophobic surfaces of Sec31A (show SEC31A Antibodies).
ALG-2 (show PDCD6 Antibodies)/Sec31A (show SEC31A Antibodies) interactions were not required for the localization of Sec31A (show SEC31A Antibodies) to ER exit sites per se but appeared to acutely regulate the stability and trafficking of the cargo receptor p24 and the distribution of the vesicle tether protein p115 (show ARHGAP4 Antibodies)
ALG-2 (show PDCD6 Antibodies) attenuates COPII budding in vitro and stabilizes the Sec23/Sec31A (show SEC31A Antibodies) complex.
The results of in vitro binding assays using purified recombinant proteins indicated that ALG-2 (show PDCD6 Antibodies) functions as a Ca(2 (show CA2 Antibodies))-dependent adaptor protein that bridges ALIX (show PDCD6IP Antibodies) and ESCRT-I (show VPS28 Antibodies) to form a ternary complex
This is the first report showing interaction of ALG-2 (show PDCD6 Antibodies) with a P-body component (PATL1 (show PATL1 Antibodies)).PATL1 (show PATL1 Antibodies) as well as DCP1A (show DCP1A Antibodies), a well-known P-body marker, co-localized with a subset of ALG-2 (show PDCD6 Antibodies).
We identify ALG14 (show ALG14 Antibodies) and ALG2 (show PDCD6 Antibodies) as novel genes in which mutations cause a congenital myasthenic syndrome
the alg2 (show PDCD6 Antibodies) binding site is one of the key determinants of the retention kinetics of Sec31A (show SEC31A Antibodies) at endoplasmic reticulum exit sites
found that targeting Requiem and Alg-2 (show PDCD6 Antibodies) did not result in extended culture viability, but resulted in an increase in maximum viable cell numbers and cumulative IVCD under fed-batch conditions
inability of the two-residue shorter ALG-2 (show PDCD6 Antibodies) isoform to bind Alix (show PDCD6IP Antibodies)
the observation that both ALG-2 (show PDCD6 Antibodies) isoforms bind Mg2 (show MCOLN1 Antibodies)+ with high affinity is the most significant finding of this study
Thus, Alg2, as a downstream mediator of Hivep3, suppresses osteogenesis, whereas it promotes chondrogenesis.
ALG-2 (show PDCD6 Antibodies) binding to Scotin (show SHISA5 Antibodies) is strictly calcium dependent, indicating a role of this interaction in calcium signaling pathways
This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Alternative splicing results in multiple transcript variants.
asparagine-linked glycosylation 2 homolog (yeast, alpha-1,3-mannosyltransferase)
, GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase
, GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase
, GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase
, alpha-1,3-mannosyltransferase ALG2
, alpha-1,3/1,6-mannosyltransferase ALG2
, asparagine-linked glycosylation 2 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase)
, asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog
, asparagine-linked glycosylation protein 2 homolog
, homolog of yeast ALG2
, hypothetical protein