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anti-Asporin (ASPN) Antibodies

ASPN encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. Additionally we are shipping Asporin Kits (40) and Asporin Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ASPN 54829 Q9BXN1
ASPN 66695 Q99MQ4
ASPN 306805  
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Top anti-Asporin Antibodies at

Showing 10 out of 41 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated EIA, IF, WB 0.1 mg Log in to see 6 to 8 Days
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-ASPN Antibody Titration: 2.5ug/mlPositive Control: HepG2 cell lysate Host: Rabbit  Target Name: ASPN  Sample Tissue: HepG2Lane A:  Primary Antibody Lane B:  Primary Antibody + Blocking Peptide Primary Antibody Concentration: 2.5 µg/mL Peptide Concentration:..0 µg/mL Lysate Quantity:.41 µg/laneGel Concentration: 12 % 100 μL Log in to see 2 to 3 Days
Human Goat Un-conjugated ELISA, WB ABIN185364 (0.3µg/ml) staining of Human Bone Marrow lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN185364 staining of ATDC5 cells (Panels A and C) and DAPI (panels B and D). Data gratefuly received from Dr. Shiro Ikegawa, SNP Research Center, RIKEN, Japan. 100 μg Log in to see 4 to 5 Days
Human Rabbit Un-conjugated IF, IHC (p), WB Western blot analysis of ASPN antibody (Center) (ABIN390536) in HL60 cell line lysates(35 µg/lane). ASPN (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma with ASPN Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated ICC, IF, WB ICC/IF Image Immunofluorescence analysis of methanol-fixed HeLa, using Asporin, antibody at 1:200 dilution. WB Image Asporin antibody [N3C1], Internal detects Asporin protein by western blot analysis. A. 30 μg A549 whole cell lysate/extract B. 30 μg H1299 whole cell lysate/extract C. 30 μg HCT116 whole cell lysate/extract 10 % SDS-PAGE Asporin antibody [N3C1], Internal , dilution: 1:1000 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC (p), WB 100 μg Log in to see 8 to 10 Days
Human Goat Un-conjugated IF, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
Human Goat Un-conjugated ICC, ELISA, WB 100 μg Log in to see 8 to 10 Days
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 2 to 3 Days

ASPN Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
, ,

, , , , ,
Mouse (Murine)

Rat (Rattus)

Top referenced anti-Asporin Antibodies

  1. Human Polyclonal Asporin Primary Antibody for EIA, IF - ABIN374529 : Hurng, Kurylo, Marshall, Webb, Ryder, Ho: Discontinuities in the human bone-PDL-cementum complex. in Biomaterials 2011 (PubMed)
    Show all 3 references for ABIN374529

  2. Human Polyclonal Asporin Primary Antibody for ELISA, WB - ABIN185364 : Kizawa, Kou, Iida, Sudo, Miyamoto, Fukuda, Mabuchi, Kotani, Kawakami, Yamamoto, Uchida, Nakamura, Notoya, Nakamura, Ikegawa: An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis. in Nature genetics 2005 (PubMed)

  3. Human Polyclonal Asporin Primary Antibody for IF, IHC (p) - ABIN390536 : Ikegawa: Expression, regulation and function of asporin, a susceptibility gene in common bone and joint diseases. in Current medicinal chemistry 2008 (PubMed)

More Antibodies against Asporin Interaction Partners

Pig (Porcine) Asporin (ASPN) interaction partners

  1. Mapping of the OGN (show OGN Antibodies) and ASPN genes and association with growth and carcass traits.

Human Asporin (ASPN) interaction partners

  1. To test the associations of ASPN variations with risk of subsequent oncologic outcomes.

  2. Collectively, our findings indicate that ASPN is upregulated and plays an oncogenic role in gastric cancer progression and metastasis by influencing the EGFR (show EGFR Antibodies) signaling pathway.

  3. Our results showed that ASPN rs13301537 T to C change and variant C genotype may contribute to knee OA risk in a Chinese Han population.

  4. this is the first case-control study in Mexican women that suggests that menopause and the D-repeat polymorphism in the ASPN gene are associated with knee OA

  5. Osteomodulin (show OMD Antibodies), osteoglycin (show OGN Antibodies), and asporin appear to be distinctly regulated in osteoarthritis labrum compared to OA cartilage.

  6. Asporin may represent a new therapeutic target molecule for the development of drugs aimed at manipulating the cancer microenvironment.

  7. This meta-analysis shows that the ASPN D14, D13, and D15 (show MRPL16 Antibodies) alleles are not associated with the development of osteoarthritis in Europeans and Asians. [Meta-Analysis]

  8. A meta-analysis suggest that the D-repeat of asporin gene (ASPN) may not be a major susceptibility locus in the Caucasian and Asian populations with knee osteoarthritis.

  9. polymorphisms within the ASPN gene could influence knee osteoarthritis susceptibility

  10. D14-PLAP-1 (show ALP Antibodies) suppressed BMP-2 (show BMP2 Antibodies) signal transduction more efficiently than D13-PLAP-1 (show ALP Antibodies); stronger affinity of D14-PLAP-1 (show ALP Antibodies) protein to BMP-2 (show BMP2 Antibodies) compared with D13-PLAP-1 (show ALP Antibodies) protein. D repeat polymorphism of PLAP-1/asporin has influence on functions of PDL cells.

Mouse (Murine) Asporin (ASPN) interaction partners

  1. inhibition of TLR2 (show TLR2 Antibodies)- and TLR4 (show TLR4 Antibodies)-induced inflammatory responses and binding abilities to TLR2 (show TLR2 Antibodies) and TLR4 (show TLR4 Antibodies)

  2. positively regulates FGF-2 (show FGF2 Antibodies) activity through a direct interaction

  3. Findings suggest that asporin is one of the important cartilage matrix proteins that binds to the ECM (show MMRN1 Antibodies) and TGF-beta1 (show TGFB1 Antibodies) and thereby modulates interactions between TGF-beta (show TGFB1 Antibodies) and its signaling receptors.

  4. PLAP-1/asporin plays a specific role in the periodontal ligament as a negative regulator of cytodifferentiation and mineralization by regulating BMP-2 (show BMP2 Antibodies) activity to prevent the periodontal ligament from developing non-physiological mineralization

  5. The findings indicate that TGF-beta1 (show TGFB1 Antibodies) induces ASPN through Smad3 (show SMAD3 Antibodies) but that this induction is indirect.

  6. Leucine-rich repeat motif 5 (LRR5) of PLAP-1/asporin, plays an important role in the PLAP-1/asporin-BMP-2 (show BMP2 Antibodies) interaction.

Xenopus laevis Asporin (ASPN) interaction partners

  1. The small leucine-rich repeat secreted protein Asporin induces eyes in Xenopus embryos through the IGF signalling pathway.

Asporin (ASPN) Antigen Profile

Protein Summary

This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with anti-Asporin (ASPN) Antibodies

  • asporin (LRR class 1) (aspn) antibody
  • asporin (ASPN) antibody
  • asporin (Aspn) antibody
  • asporin (aspn) antibody
  • 4631401G09Rik antibody
  • AA986886 antibody
  • aspnl antibody
  • bgl3 antibody
  • os3 antibody
  • plap-1 antibody
  • plap1 antibody
  • slrr1c antibody
  • wu:fk08c11 antibody
  • zgc:109936 antibody

Protein level used designations for anti-Asporin (ASPN) Antibodies

asporin , biglycan-like protein 3 , asporin (LRR class 1) , asporin proteoglycan , periodontal ligament associated protein 1 , small leucine-rich protein 1C , periodontal ligament-associated protein 1

65228 Danio rerio
739953 Pan troglodytes
100054817 Equus caballus
100192319 Sus scrofa
100410747 Callithrix jacchus
100446487 Pongo abelii
100600227 Nomascus leucogenys
54829 Homo sapiens
66695 Mus musculus
495030 Xenopus laevis
415954 Gallus gallus
610685 Canis lupus familiaris
507990 Bos taurus
306805 Rattus norvegicus
100732832 Cavia porcellus
100511749 Sus scrofa
101108885 Ovis aries
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