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anti-BAI1-Associated Protein 2 (BAIAP2) Antibodies

The protein encoded by BAIAP2 has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. Additionally we are shipping BAIAP2 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BAIAP2 10458 Q9UQB8
BAIAP2 117542 Q6GMN2
BAIAP2 108100 Q8BKX1
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Top anti-BAIAP2 Antibodies at antibodies-online.com

Showing 10 out of 127 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN184627 staining (1µg/ml) of Human Brain (Cerebellum) lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 12 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-BAIAP2 Pab (ABIN392809) is used in Western blot to detect BAIAP2 in mouse brain tissue lysate (Lane 1) and A375 cell lysate (Lane 2). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated WB BAIAP2 Antibody (C-term) (ABIN1882211) western blot analysis in K562 cell line and mouse brain tissue lysates (35 µg/lane). This demonstrates the BAIAP2 antibody detected the BAIAP2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB HEK293T cells transfected with either RC214570 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-BAIAP2 antibody (ABIN2454636), and then analyzed by flow cytometry. Anti-BAIAP2 mouse monoclonal antibody (ABIN2454636) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BAIAP2 (RC214570). 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IF, WB HEK293T cells transfected with either RC214570 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-BAIAP2 antibody (ABIN2454654), and then analyzed by flow cytometry. Anti-BAIAP2 mouse monoclonal antibody (ABIN2454654) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BAIAP2 (RC214570). 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IF, IHC, WB Anti-BAIAP2 mouse monoclonal antibody (ABIN2454882) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BAIAP2 (RC214570). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BAIAP2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-BAIAP2. 100 μL Log in to see 2 to 3 Days
$482.90
Details

BAIAP2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus) ,
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Top referenced anti-BAIAP2 Antibodies

  1. Human Polyclonal BAIAP2 Primary Antibody for EIA, IHC (p) - ABIN360705 : Fujiwara, Mammoto, Kim, Takai: Rho small G-protein-dependent binding of mDia to an Src homology 3 domain-containing IRSp53/BAIAP2. in Biochemical and biophysical research communications 2000 (PubMed)
    Show all 4 references for ABIN360705

  2. Human Polyclonal BAIAP2 Primary Antibody for IHC (p), WB - ABIN392809 : Abbott, Wells, Fallon: The insulin receptor tyrosine kinase substrate p58/53 and the insulin receptor are components of CNS synapses. in The Journal of neuroscience : the official journal of the Society for Neuroscience 1999 (PubMed)
    Show all 3 references for ABIN392809

  3. Human Monoclonal BAIAP2 Primary Antibody for WB - ABIN1882211 : Miyahara, Okamura-Oho, Miyashita, Hoshika, Yamada: Genomic structure and alternative splicing of the insulin receptor tyrosine kinase substrate of 53-kDa protein. in Journal of human genetics 2003 (PubMed)
    Show all 3 references for ABIN1882211

  4. Human Polyclonal BAIAP2 Primary Antibody for WB - ABIN374113 : Oda, Shiratsuchi, Nishimori, Inazawa, Yoshikawa, Taketani, Nakamura, Tokino: Identification of BAIAP2 (BAI-associated protein 2), a novel human homologue of hamster IRSp53, whose SH3 domain interacts with the cytoplasmic domain of BAI1. in Cytogenetics and cell genetics 1999 (PubMed)

More Antibodies against BAIAP2 Interaction Partners

Human BAI1-Associated Protein 2 (BAIAP2) interaction partners

  1. Results suggest the hypothesis that defective actin/membrane modulation in IRSp53-deficient dendritic spines may lead to social and cognitive deficits through N-methyl-d-aspartate receptor (show GRIN1 Antibodies) dysfunction.

  2. determined the alpha-synuclein (show SNCA Antibodies)-binding domain of beta-III tubulin (show TUBB Antibodies) and demonstrated that a short fragment containing this domain can suppress alpha-synuclein (show SNCA Antibodies) accumulation in the primary cultured cells

  3. BAIAP2 is related to emotional modulation of human memory strength.

  4. These above results indicated the possible involvement of BAIAP2 in the etiology of attention deficit disorder with hyperactivity, especially ADHD-I.

  5. IRSp53 adopts a closed inactive conformation that opens synergistically with the binding of human Cdc42 (show CDC42 Antibodies) to the CRIB (show SCRIB Antibodies)-PR and effector proteins, such as the tumor-promoting factor Eps8 (show EPS8 Antibodies), to the SH3 domain (show ITSN1 Antibodies).

  6. LIN7 is a novel regulator of IRSp53.

  7. mDia1 and WAVE2 (show WASF2 Antibodies) are important Src (show SRC Antibodies) homology 3 domain partners of IRSp53 in forming filopodia.

  8. Structural basis for complex formation between human IRSp53 and the translocated intimin receptor Tir of enterohemorrhagic E. coli

  9. Studied generation of filopodia with regards to the dynamic interaction established by Eps8, IRSp53 and VASP with actin filaments.

  10. A molecular dynamics study of the interaction between domain I-BAR of the IRSp53 protein and negatively charged membranes

Mouse (Murine) BAI1-Associated Protein 2 (BAIAP2) interaction partners

  1. CDC42 activation inhibits this activity and promotes IRSp53-dependent recruitment and clustering of VASP to drive actin assembly.

  2. VASP (show VASP Antibodies) physically interacted with IRSp53 in NIH-Src (show SRC Antibodies) cells and was essential for podosome formation.

  3. propose that IRSp53 is a negative regulator of myogenic differentiation which correlates with the observed down regulation of IRSp53 expression during myoblast differentiation to myotubes

  4. mDia1 and WAVE2 (show WASF2 Antibodies) are important Src (show SRC Antibodies) homology 3 domain partners of IRSp53 in forming filopodia.

  5. IRSp53, through its interaction with Eps8 (show EPS8 Antibodies), not only affects cell migration but also dictates cellular growth in cancer cells.

  6. IRSp53 and spinophilin (show PPP1R9B Antibodies) regulate localized Rac (show AKT1 Antibodies) activation by T-lymphocyte invasion and metastasis protein 1

  7. In cells spread well on a laminin substrate, IRSp53 was localised at the tips of both lamellipodia and filopodia and in in living cells during protrusion.

  8. Rac1, along with IRSp53 and Abi1 (show ABI1 Antibodies), is involved in a more complex and tight regulation of WAVE2 (show WASF2 Antibodies) than one operating solely through membrane localization.

  9. Consistent with altered synaptic plasticity, IRSp53-deficient mice exhibit cognitive deficits in the contextual fear-conditioning paradigm

  10. Formation of filopodia is dependent on the Rho family GTPase Cdc42 (show CDC42 Antibodies) and the Cdc42 effector (show FNBP1L Antibodies) IRSp53 (Baiap2).

BAIAP2 Antigen Profile

Protein Summary

The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with BAIAP2

  • BAI1-associated protein 2 (BAIAP2) antibody
  • BAI1-associated protein 2 (baiap2) antibody
  • BAI1-associated protein 2 (Baiap2) antibody
  • brain-specific angiogenesis inhibitor 1-associated protein 2 (Baiap2) antibody
  • BAIAP2 antibody
  • BAP2 antibody
  • DKFZp470L1727 antibody
  • FLAF3 antibody
  • IRSp53 antibody
  • IRSP53S antibody
  • R75030 antibody

Protein level used designations for BAIAP2

BAI1-associated protein 2 , brain-specific angiogenesis inhibitor 1-associated protein 2-like , IRS-58 , IRSp53/58 , brain-specific angiogenesis inhibitor 1-associated protein 2 , fas ligand-associated factor 3 , insulin receptor substrate p53/p58 , insulin receptor substrate protein of 53 kDa , BAI-associated protein 2 , insulin receptor substrate 53 , insulin receptor substrate p53 , insulin receptor tyrosine kinase substrate protein p53 , insulin recptor substrate p53 , insulin receptor tyrosine kinase 53 kDa substrate

GENE ID SPECIES
422077 Gallus gallus
454951 Pan troglodytes
100158528 Xenopus (Silurana) tropicalis
100172379 Pongo abelii
100428388 Macaca mulatta
10458 Homo sapiens
117542 Rattus norvegicus
403473 Canis lupus familiaris
507837 Bos taurus
108100 Mus musculus
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